Evaluation of a Web-based decision aid for people considering the APOE genetic test for Alzheimer risk

Evaluation of a Web-based decision aid for people considering the APOE genetic test for Alzheimer risk

Purpose: With the increasing interest in apolipoprotein E ( APOE ) genetic testing to estimate the risk of developing late-onset Alzheimer disease, new educational tools are needed to help people make the best decision for themselves about whether to undergo this test. This study evaluated an online...

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Bibliographic Details
Published in:Genetics in medicine Vol. 19; no. 6; pp. 676 - 682
Main Authors: Ekstract, Michael, Holtzman, Golde I., Kim, Kye Y., Willis, Susan M., Zallen, Doris T.
Format: Journal Article
Language:English
Published: New York Nature Publishing Group US 01-06-2017
Elsevier Limited
Subjects:
631/114/2398
631/208/1516
631/208/2489/1512
692/699/375/132/1283
Adult
Aged
Aged, 80 and over
Alzheimer Disease - diagnosis
Alzheimer Disease - genetics
Apolipoproteins E - genetics
Biomedical and Life Sciences
Biomedicine
Decision Support Techniques
Female
Genetic Testing
Health Status Indicators
Human Genetics
Humans
Internet
Laboratory Medicine
Male
Middle Aged
original-research-article
Young Adult
educational tool
Alzheimer disease
genetic testing
online decision aid
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Summary:Purpose: With the increasing interest in apolipoprotein E ( APOE ) genetic testing to estimate the risk of developing late-onset Alzheimer disease, new educational tools are needed to help people make the best decision for themselves about whether to undergo this test. This study evaluated an online tool to assist in this decision process. Methods: A prototype decision aid was studied in a two-part survey that collected data from participants before and after they examined the decision aid. Both surveys had multiple-choice options and opportunities for open-ended responses, yielding quantitative and qualitative information. The responses before and after use of the aid were compared for each participant. Results: A total of 1,262 individuals completed both surveys. The overall effectiveness of the decision aid was shown by three measures: 94% found the decision aid very helpful or somewhat helpful; general knowledge was increased; and some people changed their minds about APOE genetic testing, with 35% shifting to a higher likelihood of undergoing the test and 20% to a lower likelihood. Suggestions for improvements were noted and incorporated into the online tool. Conclusion: This decision aid can provide useful educational assistance to many individuals as they consider APOE genetic testing as well as facilitate further discussions with their health-care providers. Genet Med advance online publication 03 November 2016
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:1098-3600
1530-0366
DOI:10.1038/gim.2016.170