Search Results - "Eksborg, Staffan"

Risks for death after admission to pediatric intensive care (PICU)—A comparison with the general population by Hannegård Hamrin, Tova, Eksborg, Staffan

“…Objective/aim The aim of the study was to quantify excess mortality in children after admission to a Pediatric Intensive Care Unit (PICU), compared to the age…”
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Survival after PICU admission: The impact of multiple admissions and complex chronic conditions by Kalzén, Håkan, Larsson, Björn, Eksborg, Staffan, Lindberg, Lars, Edberg, Karl Erik, Frostell, Claes

“…Factors predicting survival over time after pediatric intensive care unit (PICU) admissions are not fully understood. The primary aim of the current study was…”
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Septic shock and the use of norepinephrine in an intermediate care unit: Mortality and adverse events by Hallengren, Mikael, Åstrand, Per, Eksborg, Staffan, Barle, Hans, Frostell, Claes

“…Septic shock is associated with high mortality. Aged and multimorbid patients are not always eligible for intensive care units. Norepinephrine is an accepted…”
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Pharmacokinetics and Toxicity of Sodium Selenite in the Treatment of Patients with Carcinoma in a Phase I Clinical Trial: The SECAR Study by Brodin, Ola, Eksborg, Staffan, Wallenberg, Marita, Asker-Hagelberg, Charlotte, Larsen, Erik H, Mohlkert, Dag, Lenneby-Helleday, Clara, Jacobsson, Hans, Linder, Stig, Misra, Sougat, Björnstedt, Mikael

“…Sodium selenite at high dose exerts antitumor effects and increases efficacy of cytostatic drugs in multiple preclinical malignancy models. We assessed the…”
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Fas-ligand and interleukin-6 in the cerebrospinal fluid are early predictors of hypoxic-ischemic encephalopathy and long-term outcomes after birth asphyxia in term infants by Leifsdottir, Kristin, Mehmet, Huseyin, Eksborg, Staffan, Herlenius, Eric

“…Cerebral ischemia generates neuroinflammation that can induce neural cell death. This cohort study assessed whether Fas-ligand (FasL) and interleukin (IL)-6…”
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Influence of altitude on cerebral and splanchnic oxygen saturation in critically ill children during air ambulance transport by Hannegård Hamrin, Tova, Eksborg, Staffan, Berner, Jonas, Fläring, Urban, Radell, Peter J, Engelhardt, Barbara Wilson, Mink, Richard Bruce

“…Objective The aim of the current study was to investigate how cerebral and splanchnic oxygen saturation (rSO.sub.2 -C and rSO.sub.2 -A) in critically ill…”
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Improved home management of oral pediatric anticancer drugs as a result of an intervention comprising practical training, written instructions and movie clips: A pilot study by Akkawi El Edelbi, Ranaa, Eksborg, Staffan, Ekman, Jennie, Lindemalm, Synnöve

“…Background Long term treatment of pediatric patients with oral anticancer drugs (OADs) requires the parents/caregivers to prepare the drug at home. The…”
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Manipulated Oral and Rectal Drugs in a Paediatric Swedish University Hospital, a Registry-Based Study Comparing Two Study-Years, Ten Years Apart by Andersson, Åsa C, Eksborg, Staffan, Förberg, Ulrika, Nydert, Per, Lindemalm, Synnöve

“…This is a registry-based study with the aim of describing and comparing the frequency of manipulations of solid oral and rectal medicines in 2009 and 2019 at…”
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Protective Role of Humanin on Bortezomib-Induced Bone Growth Impairment in Anticancer Treatment by ERIKSSON, Emma, WICKSTRÖM, Malin, PERUP, Lova Segerström, JOHNSEN, John I, EKSBORG, Staffan, KOGNER, Per, SÄVENDAHL, Lars

“…Bortezomib is a proteasome inhibitor currently studied in clinical trials of childhood cancers. So far, no side effects on bone growth have been reported in…”
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Chloroquine is grossly under dosed in young children with malaria: implications for drug resistance by Ursing, Johan, Eksborg, Staffan, Rombo, Lars, Bergqvist, Yngve, Blessborn, Daniel, Rodrigues, Amabelia, Kofoed, Poul-Erik

“…Plasmodium falciparum malaria is treated with 25 mg/kg of chloroquine (CQ) irrespective of age. Theoretically, CQ should be dosed according to body surface…”
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Long-term pulmonary function and quality of life in adults after extracorporeal membrane oxygenation for respiratory failure by von Bahr, Viktor, Kalzén, Håkan, Frenckner, Björn, Hultman, Jan, Frisén, K Gunilla, Lidegran, Marika K, Diaz, Sandra, Malfertheiner, Maximilian V, Millar, Jonathan E, Dobrosavljevic, Tanja, Eksborg, Staffan, Holzgraefe, Bernhard

“…Background: There is a significant long-term burden on survivors after acute respiratory distress syndrome, even 5 years after discharge. This is not well…”
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Impact of prior traumatic life events on parental early stage reactions following a child's cancer by Boman, Krister K, Kjällander, Ylva, Eksborg, Staffan, Becker, Jeremy

“…In pediatric oncology, effective clinic-based management of acute and long-term distress in families calls for investigation of determinants of parents'…”
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Effect of frequently used chemotherapeutic drugs on the cytotoxic activity of human natural killer cells by Markasz, Laszlo, Stuber, Gyorgy, Vanherberghen, Bruno, Flaberg, Emilie, Olah, Eva, Carbone, Ennio, Eksborg, Staffan, Klein, Eva, Skribek, Henriette, Szekely, Laszlo

“…Tumors are considered to be possible targets of immunotherapy using stimulated and expanded autologous or allogeneic natural killer (NK) cells mismatched for…”
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The cerebrospinal fluid proteome of preterm infants predicts neurodevelopmental outcome by Leifsdottir, Kristin, Jost, Kerstin, Siljehav, Veronica, Thelin, Eric P., Lassarén, Philipp, Nilsson, Peter, Haraldsson, Ásgeir, Eksborg, Staffan, Herlenius, Eric

“…Background Survival rate increases for preterm infants, but long-term neurodevelopmental outcome predictors are lacking. Our primary aim was to determine…”
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Selective loss of vaccine-specific memory B cells in a rhesus macaque model of chemotherapy: influence of doxorubicin on immunological memory by Ingelman-Sundberg, Hanna M, Saghafian-Hedengren, Shanie, Jahnmatz, Maja, Eksborg, Staffan, Jonker, Margreet, Nilsson, Anna

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Increased Apoptosis Occurring During the First Wave of Spermatogenesis Is Stage-Specific and Primarily Affects Midpachytene Spermatocytes in the Rat Testis by JAHNUKAINEN, Kirsi, CHRYSIS, Dionisios, MI HOU, PARVINEN, Martti, EKSBORG, Staffan, SÖDER, Olle

“…The physiological apoptosis that occurs in immature testis appears to be necessary for the maturation of this tissue. Thus, inhibition of the early apoptotic…”
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Prevention of cisplatin-induced hearing loss by administration of a thiosulfate-containing gel to the middle ear in a guinea pig model by Berglin, Cecilia Engmér, Pierre, Pernilla Videhult, Bramer, Tobias, Edsman, Katarina, Ehrsson, Hans, Eksborg, Staffan, Laurell, Göran

“…Purpose Thiosulfate may reduce cisplatin-induced ototoxicity, most likely by relieving oxidative stress and by forming inactive platinum complexes. This study…”
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Segmental distribution of high-volume caudal anesthesia in neonates, infants, and toddlers as assessed by ultrasonography by Lundblad, Märit, Lönnqvist, Per-Arne, Eksborg, Staffan, Marhofer, Peter

“…Background:  The aim of this prospective, age‐stratified, observational study was to determine the cranial extent of spread of a large volume (1.5 ml·kg−1,…”
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Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets by Baryawno, Ninib, Sveinbjörnsson, Baldur, Eksborg, Staffan, Orrego, Abiel, Segerström, Lova, Oqvist, Carl Otto, Holm, Stefan, Gustavsson, Bengt, Kågedal, Bertil, Kogner, Per, Johnsen, John Inge

“…Prostaglandin E(2) (PGE(2)) has been shown to play important roles in several aspects of tumor development and progression. PGE(2) is synthesized from…”
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Celecoxib Prevents Neuroblastoma Tumor Development and Potentiates the Effect of Chemotherapeutic Drugs In vitro and In vivo by Ponthan, Frida, Wickström, Malin, Gleissman, Helena, Fuskevåg, Ole M, Segerström, Lova, Sveinbjörnsson, Baldur, Redfern, Christopher P F, Eksborg, Staffan, Kogner, Per, Johnsen, John I

“…Purpose: Neuroblastoma is the most common and deadly solid tumor of childhood. Cyclooxygenase-2 is expressed in clinical neuroblastoma tumors and cell lines…”
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