Search Results - "Ekman, C. J."
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Bipolar disorder type I and II show distinct relationships between cortical thickness and executive function
Published in Acta psychiatrica Scandinavica (01-10-2018)“…Objective Frontal cortical abnormalities and executive function impairment co‐occur in bipolar disorder. Recent studies have shown that bipolar subtypes differ…”
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Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis
Published in Molecular psychiatry (01-11-2016)“…Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder (BD) has been reported, the precise biological basis remains unknown,…”
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A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder
Published in Molecular psychiatry (01-10-2016)“…Elevated cerebrospinal fluid (CSF) levels of the glia-derived N -methyl- D -aspartic acid receptor antagonist kynurenic acid (KYNA) have consistently been…”
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Manic episodes are associated with grey matter volume reduction - a voxel-based morphometry brain analysis
Published in Acta psychiatrica Scandinavica (01-12-2010)“…Ekman CJ, Lind J, Rydén E, Ingvar M, Landén M. Manic episodes are associated with grey matter volume reduction — a voxel‐based morphometry brain analysis…”
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Cognitive performance and cerebrospinal fluid biomarkers of neurodegeneration: a study of patients with bipolar disorder and healthy controls
Published in PloS one (08-05-2015)“…The purpose of the present study was to investigate if cerebrospinal fluid (CSF) biomarkers of neurodegeneration are associated with cognition in bipolar…”
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Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls
Published in European neuropsychopharmacology (01-01-2015)“…Abstract Glutamate is the major excitatory neurotransmitter in the brain. Aberrations in glutamate signaling have been linked to the pathophysiology of mood…”
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Cortical thickness, volume and surface area in patients with bipolar disorder types I and II
Published in Journal of psychiatry & neuroscience (01-07-2016)“…Bipolar disorder (BD) is a common chronic psychiatric disorder mainly characterized by episodes of mania, hypomania and depression. The disorder is associated…”
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Markers of neuroinflammation and neuronal injury in bipolar disorder: Relation to prospective clinical outcomes
Published in Brain, behavior, and immunity (01-10-2017)“…Highlights • Low CSF levels of YKL-40 predicted mania/hypomania. • CSF levels of IL-8 and NF-L did not predict long-term clinical outcomes. • Assessed markers…”
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Manic episodes are related to changes in frontal cortex: a longitudinal neuroimaging study of bipolar disorder 1
Published in Brain (London, England : 1878) (01-11-2015)“…Higher numbers of manic episodes in bipolar patients has, in cross-sectional studies, been associated with less grey matter volume in prefrontal brain areas…”
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Repetitive transcranial magnetic stimulation in major depression: A three-arm parallel-group dose-response randomized pilot trial
Published in Medicine (Baltimore) (09-04-2021)“…The optimal dose (number of pulses per session) of repetitive transcranial magnetic stimulation (rTMS), using the H-coil, in major depressive disorder (MDD)…”
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P11 (S100A10) as a potential predictor of ketamine response in patients with SSRI-resistant depression
Published in Journal of affective disorders (01-07-2021)“…•Peripheral p11 levels were analysed in relation to ketamine treatment.•P11 levels were reduced in CD4+ and CD8+ T cells, though not compared to…”
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Altered Concentrations of Amyloid Precursor Protein Metabolites in the Cerebrospinal Fluid of Patients with Bipolar Disorder
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2013)“…Bipolar disorder is a psychiatric disorder characterized by recurrent episodes of mania/hypomania and depression. Progressive cognitive dysfunction such as…”
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Mapping length of inpatient treatment duration and year‐wise relapse rates in eating disordered populations in a well‐defined Western‐European healthcare region across 1998–2020
Published in International journal of methods in psychiatric research (01-12-2023)“…Objectives Updated international guideline recommendations for AN inpatient care rely on expert opinions/observational evidence and promote extended inpatient…”
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Plasma Levels of Brain-Derived Neurotrophic Factor and S100B in Relation to Antidepressant Response to Ketamine
Published in Frontiers in neuroscience (20-07-2021)“…Background Evidence demonstrates that brain-derived neurotrophic factor (BDNF) and S100 calcium-binding protein B (S100B) have a pivotal role in the…”
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Validity of diagnoses, treatment dates, and rating scales in the Swedish national quality register for electroconvulsive therapy
Published in Nordic journal of psychiatry (2022)“…The Swedish national quality register for electroconvulsive therapy (Q-ECT) contains data on patients receiving treatment with electroconvulsive therapy (ECT)…”
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Cognitive functioning in clinically stable patients with bipolar disorder I and II
Published in PloS one (23-01-2015)“…Bipolar disorder is accompanied by cognitive impairments, which persists during euthymic phases. The purpose of the present study was to identify those…”
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The Incidence of Dental Fracturing in Electroconvulsive Therapy in Sweden
Published in The journal of ECT (01-09-2020)“…OBJECTIVESOne adverse effect of electroconvulsive therapy (ECT) is dental fracture; thus, a bite guard and muscle relaxants are used to prevent it. Earlier…”
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Neurocognitive function in bipolar disorder: a comparison between bipolar I and II disorder and matched controls
Published in BMC psychiatry (07-06-2013)“…Cognitive deficits have been documented in patients with bipolar disorder. Further, it has been suggested that the degree and type of cognitive impairment…”
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Blood–cerebrospinal fluid barrier dysfunction in patients with bipolar disorder in relation to antipsychotic treatment
Published in Psychiatry research (30-07-2014)“…Abstract Blood–cerebrospinal barrier (BCB) dysfunction has previously been shown in subjects with schizophrenia and depressed patients with attempted suicide…”
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Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function
Published in Psychiatry research. Neuroimaging (30-03-2014)“…Abstract We hypothesized that psychomotor disturbances in patients with bipolar disorder are associated with morphometric changes in functionally specific…”
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