Search Results - "Eklöf, Josefin"
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Effect of low climate impact vs. high climate impact inhalers for patients with asthma and COPD-a nationwide cohort analysis
Published in Respiratory research (12-09-2024)“…Chronic obstructive pulmonary disease (COPD) and asthma can be treated with inhaled corticosteroids (ICS) delivered by low climate impact inhalers (dry powder…”
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2
Use of inhaled corticosteroids and risk of acquiring Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
Published in Thorax (01-06-2022)“…Inhaled corticosteroids (ICS) are commonly used to treat COPD and are associated with increased risk of pneumonia. The aim of this study was to assess if…”
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3
Social Distancing in Relation to Severe Exacerbations of Chronic Obstructive Pulmonary Disease: A Nationwide Semi-Experimental Study During the COVID-19 Pandemic
Published in American journal of epidemiology (24-03-2022)“…Abstract Social distancing measures introduced on March 12, 2020, in Denmark during the COVID-19 pandemic may affect non–COVID-19 admissions for severe acute…”
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4
Mortality and exacerbations associated with Stenotrophomonas maltophilia in chronic obstructive pulmonary disease. A regional cohort study of 22,689 outpatients
Published in Respiratory research (26-09-2023)“…Abstract Objectives The clinical significance of Stenotrophomonas maltophilia in patients with COPD is poorly understood. We aimed to determine whether a lower…”
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5
Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial
Published in The lancet respiratory medicine (01-08-2019)“…Treatment with systemic corticosteroids in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) is associated with debilitating…”
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6
Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial
Published in The European respiratory journal (01-01-2022)“…Combining the antibiotic azithromycin and hydroxychloroquine induces airway immunomodulatory effects, with the latter also having antiviral properties. This…”
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7
Hospitalization for chronic obstructive pulmonary disease and pneumonia: association with the dose of inhaled corticosteroids. A nation-wide cohort study of 52 100 outpatients
Published in Clinical microbiology and infection (01-04-2023)“…International guidelines only advocate the use of inhaled corticosteroids (ICSs) in patients with chronic obstructive pulmonary disease (COPD) experiencing…”
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8
Antibiotic treatment in acute exacerbation of COPD: patient outcomes with amoxicillin vs. amoxicillin/clavulanic acid-data from 43,636 outpatients
Published in Respiratory research (07-01-2021)“…For antibiotic treatment of Acute exacerbations of COPD (AECOPD) the National guidelines in Denmark recommend either first choice amoxicillin 750 mg TID (AMX)…”
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9
Effect of different corticosteroid regimes for hospitalised patients with exacerbated COPD: pooled analysis of individual participant data from the REDUCE and CORTICO-COP trials
Published in Respiratory research (21-05-2021)“…Abstract Background Systemic corticosteroid administration for severe acute exacerbations of COPD (AECOPD) reduces the duration of hospital stays…”
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10
Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease
Published in Diabetes, obesity & metabolism (01-08-2020)“…Aim To determine the risk of type 2 diabetes onset associated with accumulated inhaled corticosteroids (ICS) dose during the previous year in patients with…”
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11
COPD exacerbations: the impact of long versus short courses of oral corticosteroids on mortality and pneumonia: nationwide data on 67 000 patients with COPD followed for 12 months
Published in BMJ open respiratory research (2019)“…IntroductionA large group of patients with chronic obstructive pulmonary disease (COPD) are exposed to an overload of oral corticosteroids (OCS) due to…”
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12
Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
Published in Clinical microbiology and infection (01-07-2022)“…It is unclear whether recurrent sputum culture with Pseudomonas aeruginosa from patients with chronic obstructive pulmonary disease (COPD) is caused by…”
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13
Inhaled corticosteroids and risk of lower respiratory tract infection with Moraxella catarrhalis in patients with chronic obstructive pulmonary disease
Published in BMJ open respiratory research (01-08-2023)“…BackgroundUse of inhaled corticosteroids (ICS) is common in patients with chronic obstructive pulmonary disease (COPD) and has been associated with an…”
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14
Antibiotic treatment adequacy and death among patients with Pseudomonas aeruginosa airway infection
Published in PloS one (31-12-2019)“…The effect of antibiotics on survival in patients with pulmonary Pseudomonas aeruginosa is controversial. The aim of this study is to i) determine the…”
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15
SARS-CoV-2 and risk of psychiatric hospital admission and use of psychopharmaceuticals: A nationwide registry study of 4,585,083 adult Danish citizens
Published in European psychiatry (07-06-2023)“…Current evidence on the risk of admission- or medication-requiring psychiatric sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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16
Psychiatric Adverse Effects of Montelukast—A Nationwide Cohort Study
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-07-2023)“…Recent observational studies suggest that the leukotriene receptor antagonist montelukast may have neuropsychiatric adverse effects; however, results are…”
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17
Hydroxychloroquine as a primary prophylactic agent against SARS-CoV-2 infection: A cohort study
Published in International journal of infectious diseases (01-07-2021)“…•Largest cohort study on hydroxychloroquine prophylaxis for coronavirus disease 2019 to date.•Included all users of hydroxychloroquine in Denmark before the…”
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Bone turnover biomarkers in COPD patients randomized to either a regular or shortened course of corticosteroids: a substudy of the randomized controlled CORTICO-COP trial
Published in Respiratory research (12-10-2020)“…Abstract Background Long-term treatment with corticosteroids causes loss of bone density, but the effects of using short-term high-dose systemic-corticosteroid…”
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AM/PM dosing of LAMA for COPD: a randomized controlled trial protocol using digital recruitment and registries
Published in Frontiers in medicine (06-08-2024)“…Long-acting muscarinic antagonists (LAMAs) reduce the risk of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), usually taken once daily…”
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20
Inhaled corticosteroids and Stenotrophomonas maltophilia in outpatients with chronic obstructive pulmonary disease: a retrospective cohort study
Published in BMJ open respiratory research (09-03-2024)“…ObjectivesInhaled corticosteroids (ICS) are widely used in patients with chronic obstructive pulmonary disease (COPD). However, ICS are associated with an…”
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