Death Patterns in Sickle Cell Anemia

Death Patterns in Sickle Cell Anemia

In Ibadan, Nigeria, 28 patients with sickle cell disease (hemoglobin SS and SC) died and were autopsied. Fifty percent of these had died by the age of 5 years, as did 21 (68%) with homozygous hemoglobin SS disease. No death occurred in infancy or childhood among the patients with hemoglobin SC disea...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association Vol. 233; no. 8; pp. 889 - 890
Main Authors: Attah, Edward 'B, Ekere, Mayen C
Format: Journal Article
Language:English
Published: United States American Medical Association 25-08-1975
Subjects:
Adolescent
Adult
Age Factors
Anemia, Sickle Cell - blood
Anemia, Sickle Cell - genetics
Anemia, Sickle Cell - mortality
Autopsy
Child
Child, Preschool
Death, Sudden
Female
Hemoglobin C
Hemoglobin, Sickle
Heterozygote
Homozygote
Humans
Infant
Male
Middle Aged
Nigeria
Phenotype
Nigeria
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Summary:In Ibadan, Nigeria, 28 patients with sickle cell disease (hemoglobin SS and SC) died and were autopsied. Fifty percent of these had died by the age of 5 years, as did 21 (68%) with homozygous hemoglobin SS disease. No death occurred in infancy or childhood among the patients with hemoglobin SC disease. Serious intercurrent disease that could have been responsible for death was present in ten patients (36%). The type and frequency of intercurrent disease appears to be related to the environment.(JAMA 233:889-890, 1975)
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0098-7484
1538-3598
DOI:10.1001/jama.1975.03260080051021