Search Results - "Ekem, Ivy"
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A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analysis
Published in Annals of hematology (01-09-2020)“…Vasculopathy is a hallmark of sickle cell disease ultimately resulting in chronic end organ damage. Leg ulcer is one of its sequelae, occurring in ~ 5–10% of…”
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Reversible hyperpigmentation in Vitamin B12 deficiency: an addisonian mimic in clinical practice
Published in PAMJ clinical medicine (01-11-2020)“…Vitamin B12 deficiency may present with gastrointestinal, haematologic, dermatologic and neuropsychiatric signs and symptoms. Skin hyperpigmentation is a…”
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3
Elevated Proangiogenic Markers are Associated with Vascular Complications within Ghanaian Sickle Cell Disease Patients
Published in Medical sciences (Basel) (27-06-2018)“…Sickle cell disease (SCD) is an inherited blood disorder that can result in vasculopathy and end organ damage. Angiogenesis has been implicated as a key…”
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Levels of Soluble Endothelium Adhesion Molecules and Complications among Sickle Cell Disease Patients in Ghana
Published in Diseases (21-04-2018)“…Soluble adhesion molecules are involved in the gathering and joining of inflammatory cells to vascular endothelium. Therefore, they serve as potential markers…”
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Association between eNOS Gene Polymorphism (T786C and VNTR) and Sickle Cell Disease Patients in Ghana
Published in Diseases (29-09-2018)“…Endothelial nitric oxide synthase (eNOS) variants have been found to be associated with several vascular disorders as well as the pathogenesis of sickle cell…”
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A Preliminary Study of the Suitability of Archival Bone Marrow and Peripheral Blood Smears for Diagnosis of CML Using FISH
Published in Advances in hematology (2014)“…FISH is a molecular cytogenetic technique enabling rapid detection of genetic abnormalities. Facilities that can run fresh/wet samples for molecular diagnosis…”
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A case-control study of prevalence of anemia among patients with type 2 diabetes
Published in Journal of medical case reports (04-05-2016)“…Anemia is defined as a reduction in the hemoglobin concentration of blood, which consequently reduces the oxygen-carrying capacity of red blood cells such that…”
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8
APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans
Published in The New England journal of medicine (26-10-2024)“…Apolipoprotein L1 gene ( ) variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD…”
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Global geographic differences in healthcare utilization for sickle cell disease pain crises in the CASiRe cohort
Published in Blood cells, molecules, & diseases (01-12-2021)“…Sickle cell disease (SCD) is characterized by frequent, unpredictable pain episodes and other vaso-occlusive crises (VOCs) leading to significant healthcare…”
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10
Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study
Published in Scientific reports (23-06-2022)“…There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African…”
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Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study
Published in BMC cancer (25-09-2021)“…The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting…”
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Sleep Patterns and Associated Clinical Correlates Amongst Ghanaian Individuals with Sickle Cell Disease
Published in Blood (08-12-2017)“…▪ Background: Sickle cell disease (SCD) is the most commonly inherited blood disorder that affects 1 in 500 individuals of African descent worldwide and…”
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Steroid-induced dysglycaemia in patients with haematological disorders a ten-year review in a tertiary hospital in Ghana
Published in Ghana medical journal (01-06-2019)“…Glucocorticoids (steroids) play a key role in the management of multiple medical conditions including haematological disorders. This study looked at the…”
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Determinants Of Heme-Oxygenase-1 Upregulation In Patients With Sickle Cell Disease
Published in Blood (15-11-2013)“…Inflammation is a cardinal component of the pathogenesis of sickle cell disease (SCD). Increased plasma concentration of the inflammatory agonist hemin…”
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Hematological parameters in Ghanaian sickle cell disease patients
Published in Journal of blood medicine (01-01-2018)“…Effective treatment and management of sickle cell disease (SCD) has been a challenge in Africa over the years. Hematological parameters are very useful…”
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16
Hypersegmented neutrophils and reversible hyperpigmentation in vitamin B(12) deficiency in Ghana
Published in BMJ case reports (2009)“…The present report concerns three cases of vitamin B(12) deficiency in Ghana. One case presented in the expected textbook manner with neurological signs,…”
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Ocular manifestations of sickle cell disease at the Korle-bu Hospital, Accra, Ghana
Published in European journal of ophthalmology (01-07-2011)“…To determine the magnitude and pattern of ocular manifestations in sickle cell disease at Korle-bu Hospital, Accra, Ghana. Hospital-based cross-sectional study…”
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62 - A 28-Year-Old Man from Ghana With a Chronic Ulcer on His Ankle
Published in Clinical Cases in Tropical Medicine (2022)Get full text
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A 28-Year-Old Man from Ghana With a Chronic Ulcer on His Ankle
Published in Clinical Cases in Tropical Medicine (01-01-2022)Get full text
Book Chapter -
20
Ocular Manifestations of Sickle Cell Disease at the Korlebu Hospital, Accra, Ghana
Published in European journal of ophthalmology (01-07-2011)“…Purpose TO determine the magnitude and pattern of ocular manifestations in sickle cell disease at Korlebu Hospital, Accra, Ghana. Methods Hospital-based…”
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Journal Article