Search Results - "Ekberg, Jenny A K"
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Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion
Published in Clinical microbiology reviews (01-10-2014)“…The brain is well protected against microbial invasion by cellular barriers, such as the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier…”
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Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer’s disease risk
Published in Scientific reports (17-02-2022)“…Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central nervous system (CNS). Recently, the link between C. pneumoniae CNS…”
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In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment
Published in Scientific reports (13-01-2022)“…Peripheral glial cell transplantation with Schwann cells (SCs) is a promising approach for treating spinal cord injury (SCI). However, improvements are needed…”
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Low-dose curcumin stimulates proliferation, migration and phagocytic activity of olfactory ensheathing cells
Published in PloS one (31-10-2014)“…One of the promising strategies for neural repair therapies is the transplantation of olfactory ensheathing cells (OECs) which are the glial cells of the…”
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Author Correction: In vitro modulation of Schwann cell behavior by VEGF and PDGF in an inflammatory environment
Published in Scientific reports (24-05-2022)Get full text
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Antimicrobial responses of peripheral and central nervous system glia against Staphylococcus aureus
Published in Scientific reports (21-05-2021)“…Staphylococcus aureus infections of the central nervous system are serious and can be fatal. S. aureus is commonly present in the nasal cavity, and after…”
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Why are olfactory ensheathing cell tumors so rare?
Published in Cancer cell international (11-10-2019)“…The glial cells of the primary olfactory nervous system, olfactory ensheathing cells (OECs), are unusual in that they rarely form tumors. Only 11 cases, all of…”
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Three-dimensional cell culture can be regulated by vibration: low-frequency vibration increases the size of olfactory ensheathing cell spheroids
Published in Journal of biological engineering (16-05-2019)“…Olfactory ensheathing cell (OEC) transplantation is emerging as a promising therapy for spinal cord injuries. However, outcomes are inconsistent, and the…”
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Advances in Electrospun Nerve Guidance Conduits for Engineering Neural Regeneration
Published in Pharmaceutics (18-01-2022)“…Injuries to the peripheral nervous system result in devastating consequences with loss of motor and sensory function and lifelong impairments. Current…”
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Generation of three-dimensional multiple spheroid model of olfactory ensheathing cells using floating liquid marbles
Published in Scientific reports (14-10-2015)“…We describe a novel protocol for three-dimensional culturing of olfactory ensheathing cells (OECs), which can be used to understand how OECs interact with…”
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Naked Liquid Marbles: A Robust Three-Dimensional Low-Volume Cell-Culturing System
Published in ACS applied materials & interfaces (13-03-2019)“…Three-dimensional (3D) multicellular structures allow cells to behave and interact with each other in a manner that mimics the in vivo environment. In recent…”
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Designing Olfactory Ensheathing Cell Transplantation Therapies: Influence of Cell Microenvironment
Published in Cell Transplantation (2022)“…Olfactory ensheathing cell (OEC) transplantation is emerging as a promising treatment option for injuries of the nervous system. OECs can be obtained…”
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Book Review Journal Article -
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Neuron-fibrous scaffold interfaces in the peripheral nervous system: a perspective on the structural requirements
Published in Neural regeneration research (01-09-2022)“…The nerves of the peripheral nervous system are not able to effectively regenerate in cases of severe neural injury. This can result in debilitating…”
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Olfactory ensheathing cells are the main phagocytic cells that remove axon debris during early development of the olfactory system
Published in Journal of comparative neurology (1911) (15-02-2015)“…ABSTRACT During development of the primary olfactory system, axon targeting is inaccurate and axons inappropriately project within the target layer or…”
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Burkholderia pseudomallei Rapidly Infects the Brain Stem and Spinal Cord via the Trigeminal Nerve after Intranasal Inoculation
Published in Infection and immunity (01-09-2016)“…Infection with Burkholderia pseudomallei causes melioidosis, a disease with a high mortality rate (20% in Australia and 40% in Southeast Asia). Neurological…”
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Burkholderia pseudomallei invades the olfactory nerve and bulb after epithelial injury in mice and causes the formation of multinucleated giant glial cells in vitro
Published in PLoS neglected tropical diseases (01-01-2020)“…The infectious disease melioidosis is caused by the bacterium Burkholderia pseudomallei. Melioidosis is characterised by high mortality and morbidity and can…”
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The serrulatane diterpenoid natural products RAD288 and RAD289 stimulate properties of olfactory ensheathing cells useful for neural repair therapies
Published in Scientific reports (06-07-2018)“…Olfactory ensheathing cells (OECs) are being trialled for cell transplantation therapies for neural repair as they have unique properties which can enhance…”
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Reliable cell purification and determination of cell purity: crucial aspects of olfactory ensheathing cell transplantation for spinal cord repair
Published in Neural regeneration research (01-11-2020)“…Transplantation of olfactory ensheathing cells, the glia of the primary olfactory nervous system, has been trialed for spinal cord injury repair with promising…”
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Streptococcus agalactiae Infects Glial Cells and Invades the Central Nervous System via the Olfactory and Trigeminal Nerves
Published in Frontiers in cellular and infection microbiology (24-02-2022)“…causes neonatal meningitis and can also infect the adult central nervous system (CNS). can cross the blood-brain barrier but may also reach the CNS other…”
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Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis
Published in mBio (15-04-2014)“…ABSTRACT Melioidosis is a potentially fatal disease that is endemic to tropical northern Australia and Southeast Asia, with a mortality rate of 14 to 50%. The…”
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