Search Results - "Ekaterina A Potter"
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The New General Biological Property of Stem-like Tumor Cells (Part II: Surface Molecules, Which Belongs to Distinctive Groups with Particular Functions, Form a Unique Pattern Characteristic of a Certain Type of Tumor Stem-like Cells)
Published in International journal of molecular sciences (13-12-2022)“…An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs), to internalize extracellular double-stranded DNA…”
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Impact of Double-Stranded RNA Internalization on Hematopoietic Progenitors and Krebs-2 Cells and Mechanism
Published in International journal of molecular sciences (01-03-2023)“…It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this…”
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Oncolytic Effect of Adenoviruses Serotypes 5 and 6 Against U87 Glioblastoma Cancer Stem Cells
Published in Anticancer research (01-11-2019)“…Background/Aim: Oncolytic adenoviruses are promising therapeutic agents against both the bulk of tumor cells and cancer stem cells. The present study intended…”
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The new general biological property of stem-like tumor cells Part I. Peculiarities of the process of the double-stranded DNA fragments internalization into stem-like tumor cells
Published in Frontiers in genetics (08-09-2022)“…Stem-like tumor cells of ascites carcinoma Krebs-2 and Epstein-Barr virus-induced B-lymphoma were shown to possess the innate capability of binding and…”
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Cancer Stem Cells: Emergent Nature of Tumor Emergency
Published in Frontiers in genetics (16-11-2018)“…A functional analysis of 167 genes overexpressed in Krebs-2 tumor initiating cells was performed. In the first part of the study, the genes were analyzed for…”
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Identification of the xenograft and its ascendant sphere-forming cell line as belonging to EBV-induced lymphoma, and characterization of the status of sphere-forming cells
Published in Cancer cell international (06-05-2019)“…We have characterized the human cell line arised from the Epstein-Barr virus (EBV) positive multiple myeloma aspirate subjected to the long-term cultivation…”
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Experimental Comparison of the In Vivo Efficacy of Two Novel Anticancer Therapies
Published in Anticancer research (01-07-2021)“…Background/Aim: We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local…”
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Characterization of biological peculiarities of the radioprotective activity of double-stranded RNA isolated from Saccharomyces сerevisiae
Published in International journal of radiation biology (01-09-2020)“…Protection from ionizing radiation is the most important component in the curing malignant neoplasms, servicing atomic reactors, and resolving the situations…”
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Approbation of the Cancer Treatment Approach Based on the Eradication of TAMRA+ Cancer Stem Cells in a Model of Murine Cyclophosphamide Resistant Lymphosarcoma
Published in Anticancer research (01-02-2020)“…We previously have described the "3+1" tumors cure approach consisting of individual time schedule of cyclophosphamide and dsDNA preparation administrations…”
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Efficacy of a new cancer treatment strategy based on eradication of tumor-initiating stem cells in a mouse model of Krebs-2 solid adenocarcinoma
Published in Oncotarget (19-06-2018)“…Krebs-2 solid carcinoma was cured using a new "3+1" strategy for eradication of Krebs-2 tumor-initiating stem cells. This strategy was based on synchronization…”
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Novel Cancer Stem Marker and Its Applicability for Grading Primary Human Gliomas
Published in Technology in cancer research & treatment (01-01-2018)“…Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize…”
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Gene expression profiling of tumor-initiating stem cells from mouse Krebs-2 carcinoma using a novel marker of poorly differentiated cells
Published in Oncotarget (07-02-2017)“…Using the ability of poorly differentiated cells to natively internalize fragments of extracellular double-stranded DNA as a marker, we isolated a tumorigenic…”
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Karanahan: A Potential New Treatment Option for Human Breast Cancer and Its Validation in a Clinical Setting
Published in Breast cancer : basic and clinical research (2022)“…Introduction: Karanahan, a cancer treatment technology aimed at eradicating tumor-initiating stem cells, has already proven effective in 7 tumor models…”
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A strategy to eradicate well-developed Krebs-2 ascites in mice
Published in Oncotarget (08-03-2016)“…We describe the strategy, which allows curing experimental mice engrafted with Krebs-2 ascites. The strategy is based on the facts that i) Krebs-2…”
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Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human glioblastoma
Published in Cancer biology & medicine (01-08-2021)“…Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgical excision extremely difficult; meanwhile…”
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Features of monocyte-derived dendritic cells encompassing a rare subpopulation of cells that are capable of natural internalization of extracellular dsDNA
Published in European cytokine network (01-06-2019)“…The present study demonstrates that monocyte-derived dendritic cells (moDCs) produced in vitro using a GM-CSF and IFN-α differentiation protocol encompass a…”
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Ultrastructural analysis of the Krebs-2 ascites cancer cells treated with extracellular double-stranded DNA preparation
Published in Ultrastructural pathology (02-01-2019)“…Electron-microscopic analysis of the ultrastructure of the Krebs-2 carcinoma ascites cells in the first 90 min immediately after their exposure to fragmented…”
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Properties of internalization factors contributing to the uptake of extracellular DNA into tumor-initiating stem cells of mouse Krebs-2 cell line
Published in Stem cell research & therapy (25-05-2016)“…Previously, we demonstrated that poorly differentiated cells of various origins, including tumor-initiating stem cells present in the ascites form of mouse…”
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Five-year disease-free survival among stage II-IV breast cancer patients receiving FAC and AC chemotherapy in phase II clinical trials of Panagen
Published in BMC cancer (18-08-2016)“…We report on the results of a phase II clinical trial of Panagen (tablet form of fragmented human DNA preparation) in breast cancer patients (placebo group n =…”
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Nonadherent Spheres With Multiple Myeloma Surface Markers Contain Cells that Contribute to Sphere Formation and Are Capable of Internalizing Extracellular Double-Stranded DNA
Published in Clinical lymphoma, myeloma and leukemia (01-10-2016)“…We present phenotypic analysis of free-floating spheres derived from the bone marrow clonogenic aspirate of a multiple myeloma patient. Besides…”
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