Search Results - "Ek Vitorin, Jose F"

MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension by Babicheva, Aleksandra, Ayon, Ramon J, Zhao, Tengteng, Ek Vitorin, Jose F, Pohl, Nicole M, Yamamura, Aya, Yamamura, Hisao, Quinton, Brooke A, Ba, Manqing, Wu, Linda, Ravellette, Keeley S, Rahimi, Shamin, Balistrieri, Francesca, Harrington, Angela, Vanderpool, Rebecca R, Thistlethwaite, Patricia A, Makino, Ayako, Yuan, Jason X-J

“…Downregulated expression of K channels and decreased K currents in pulmonary artery smooth muscle cells (PASMC) have been implicated in the development of…”
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Patch clamp studies on TRPV4-dependent hemichannel activation in lens epithelium by Ek-Vitorin, Jose F, Shahidullah, Mohammad, Lopez Rosales, Joaquin E, Delamere, Nicholas A

“…ATP release from the lens hemichannels has been explained as a response to TRPV4 activation when the lens is subjected to osmotic swelling. To explore the…”
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Regulation of gap junctional charge selectivity in cells coexpressing connexin 40 and connexin 43 by Heyman, Nathanael S, Kurjiaka, David T, Ek Vitorin, Jose F, Burt, Janis M

“…Expression of connexin 40 (Cx40) and Cx43 in cardiovascular tissues varies as a function of age, injury, and development with unknown consequences on the…”
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Structural basis for the selective permeability of channels made of communicating junction proteins by Ek-Vitorin, Jose F., Burt, Janis M.

“…The open state(s) of gap junction channels is evident from their permeation by small ions in response to an applied intercellular…”
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Selectivity of Connexin 43 Channels Is Regulated Through Protein Kinase C–Dependent Phosphorylation by Ek-Vitorin, Jose F, King, Timothy J, Heyman, Nathanael S, Lampe, Paul D, Burt, Janis M

“…Coordinated contractile activation of the heart and resistance to ischemic injury depend, in part, on the intercellular communication mediated by Cx43-composed…”
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Structural Determinants and Proliferative Consequences of Connexin 37 Hemichannel Function in Insulinoma Cells by Good, Miranda E., Ek-Vitorín, José F., Burt, Janis M.

“…Connexin (Cx) 37 suppresses vascular and cancer cell proliferation. The C terminus and a channel able to function are necessary, and neither by itself is…”
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Phosphorylation of Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function by Liu, Jialu, Ek Vitorin, Jose F., Weintraub, Susan T., Gu, Sumin, Shi, Qian, Burt, Janis M., Jiang, Jean X.

“…Phosphorylation of connexins is an important mechanism regulating gap junction channels. However, the role(s) of connexin (Cx) phosphorylation in vivo are…”
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Extracellular Loop Cysteine Mutant of Cx37 Fails to Suppress Proliferation of Rat Insulinoma Cells by Good, Miranda E., Ek-Vitorín, José F., Burt, Janis M.

“…Although a functional pore domain is required for connexin 37 (Cx37)–mediated suppression of rat insulinoma (Rin) cell proliferation, it is unknown whether…”
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The Role of Gap Junctions Dysfunction in the Development of Cataracts: From Loss of Cell-to-Cell Transfer to Blurred Vision-Review by Ek-Vitorin, Jose F, Jiang, Jean X

“…Mutations of lens connexins are linked to congenital cataracts. However, the role of connexin mutations in the development of age-related lens opacification…”
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The lipidated connexin mimetic peptide SRPTEKT- Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform by Cotter, Maura L, Boitano, Scott, Lampe, Paul D, Solan, Joell L, Vagner, Josef, Ek-Vitorin, Jose F, Burt, Janis M

“…Connexin (Cx) mimetic peptides derived from extracellular loop II sequences (e.g., Gap27: SRPTEKTIFII; Peptide5: VDCFLSRPTEKT) have been used as reversible,…”
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Call for Special Issue Papers: Bioelectrical Signaling via Gap Junctions : Deadline for Manuscript Submission: March 1, 2023 by Ek Vitorin, Jose F, Fang, Jennifer S

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Quantification of gap junction selectivity by Ek-Vitorín, Jose F, Burt, Janis M

“…Gap junctions, which are essential for functional coordination and homeostasis within tissues, permit the direct intercellular exchange of small molecules. The…”
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Channel Behavior and Voltage Gating of a Cx43 Mutant Simulating Preconditioning by Ek-Vitorin, Jose F, Silva-Mendoza, Diego, Pontifex, Tasha K, Burt, Janis M

“…Ischemic preconditioning induces lateralization and dephosphorylation of Connexin 43 (Cx43). However, the Cx43 protein that remains at intercalated disks may…”
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Hetero-Domain Interactions as a Mechanism for the Regulation of Connexin Channels by Stergiopoulos, Kathleen, Alvarado, Jose Luis, Mastroianni, Marta, Ek-Vitorin, Jose F, Taffet, Steven M, Delmar, Mario

“…Previous studies have shown that chemical regulation of connexin43 (Cx43) depends on the presence of the carboxyl terminal (CT) domain. A particle-receptor (or…”
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Cx43 Channel Gating and Permeation: Multiple Phosphorylation-Dependent Roles of the Carboxyl Terminus by Ek-Vitorín, José F, Pontifex, Tasha K, Burt, Janis M

“…Connexin 43 (Cx43), a gap junction protein seemingly fit to support cardiac impulse propagation and synchronic contraction, is phosphorylated in normoxia by…”
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Determinants of Cx43 Channel Gating and Permeation: The Amino Terminus by Ek Vitorín, José F., Pontifex, Tasha K., Burt, Janis M.

“…Separate connexin domains partake in proposed gating mechanisms of gap junction channels. The amino-terminus (NT) domains, which contribute to voltage sensing,…”
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Coexpression of Connexins 40 and 43 Enhances the pH Sensitivity of Gap Junctions: A Model for Synergistic Interactions Among Connexins by Gu, Hong, Ek-Vitorin, Jose F, Taffet, Steven M, Delmar, Mario

“…Gap junctions are formed by oligomerization of a protein called connexin. Most cells express more than one connexin isotype. Atrial myocytes, for example,…”
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Connexin Connections: A Special Issue on Gap Junctions by Fang, Jennifer S., Ek-Vitorin, Jose F.

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Connexins: A Brief Overview by Fang, Jennifer S., Ek-Vitorin, Jose F.

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Activation of the Calcium Sensing Receptor potentially inhibits Kv1.5 channel activity by Ayon, Ramon J, Tang, Haiyang, Yee, Allison M, Dash, Swetaleena, Ek‐Vitorin, Jose F, Makino, Ayako, Yuan, Jason X.‐J.

“…Abstract only The Calcium sensing receptor (CaSR) is class of G protein coupled receptors (GPCR) that can be activated by extracellular Ca 2+ and Mg 2+ …”
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