Search Results - "Ejsmont, Radoslaw"
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A Genome-Scale Resource for In Vivo Tag-Based Protein Function Exploration in C. elegans
Published in Cell (17-08-2012)“…Understanding the in vivo dynamics of protein localization and their physical interactions is important for many problems in biology. To enable systematic…”
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A neurodevelopmental origin of behavioral individuality in the Drosophila visual system
Published in Science (American Association for the Advancement of Science) (06-03-2020)“…The genome versus experience dichotomy has dominated understanding of behavioral individuality. By contrast, the role of nonheritable noise during brain…”
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Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex
Published in Developmental cell (24-10-2016)“…The axonal wiring molecule Slit and its Round-About (Robo) receptors are conserved regulators of nerve cord patterning. Robo receptors also contribute to…”
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A genome-wide resource for the analysis of protein localisation in Drosophila
Published in eLife (20-02-2016)“…The Drosophila genome contains >13000 protein-coding genes, the majority of which remain poorly investigated. Important reasons include the lack of antibodies…”
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A Temporal Transcriptional Switch Governs Stem Cell Division, Neuronal Numbers, and Maintenance of Differentiation
Published in Developmental cell (09-04-2018)“…The importance of producing the correct numbers of neurons during development is illustrated by both evolutionary enhancement of cognitive capacities in larger…”
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A toolkit for high-throughput, cross-species gene engineering in Drosophila
Published in Nature methods (01-06-2009)“…We generated two complementary genomic fosmid libraries for Drosophila melanogaster and Drosophila pseudoobscura that permit seamless modification of large…”
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Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila
Published in PloS one (12-02-2019)“…FOXP proteins form a subfamily of evolutionarily conserved transcription factors involved in the development and functioning of several tissues, including the…”
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In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura
Published in PloS one (28-01-2010)“…Systematic, large-scale RNA interference (RNAi) approaches are very valuable to systematically investigate biological processes in cell culture or in tissues…”
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The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics
Published in Genes (13-05-2014)“…For more than 100 years now, the fruit fly Drosophila melanogaster has been at the forefront of our endeavors to unlock the secrets of the genome. From the…”
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Journal Article Book Review -
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Prediction of the structure of the common perimitochondrial localization signal of nuclear transcripts in yeast
Published in Acta biochimica polonica (01-01-2007)“…Many nuclear genes encoding mitochondrial proteins require specific localization of their mRNAs to the vicinity of mitochondria for proper expression. Studies…”
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Production of fosmid genomic libraries optimized for liquid culture recombineering and cross-species transgenesis
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…Genomic DNA libraries are a valuable source of large constructs that can contain all the regulatory elements necessary for recapitulating wild-type gene…”
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Recombination-mediated genetic engineering of large genomic DNA transgenes
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…Faithful gene activity reporters are a useful tool for evo-devo studies enabling selective introduction of specific loci between species and assaying the…”
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