Search Results - "Eivers, Edward"
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Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal
Published in Cell (30-11-2007)“…BMP receptors determine the intensity of BMP signals via Smad1 C-terminal phosphorylations. Here we show that a finely controlled cell biological pathway…”
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Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling
Published in Scientific reports (31-08-2016)“…Bone morphogenetic proteins (BMPs) are growth factors that provide essential signals for normal embryonic development and adult tissue homeostasis. A key step…”
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Yeast casein kinase 2 governs morphology, biofilm formation, cell wall integrity, and host cell damage of Candida albicans
Published in PloS one (06-11-2017)“…The regulatory networks governing morphogenesis of a pleomorphic fungus, Candida albicans are extremely complex and remain to be completely elucidated. This…”
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Asymmetric mitosis: Unequal segregation of proteins destined for degradation
Published in Proceedings of the National Academy of Sciences - PNAS (03-06-2008)“…Mitotic cell division ensures that two daughter somatic cells inherit identical genetic material. Previous work has shown that signaling by the Smad1…”
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Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
Published in Genes & development (15-12-2003)“…How do very diverse signaling pathways induce neural differentiation in Xenopus? Anti-BMP (Chordin), FGF8, and IGF2 signals are integrated in the embryo via…”
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Integrating positional information at the level of Smad1/5/8
Published in Current opinion in genetics & development (01-08-2008)“…The intensity of the BMP signal is determined by cell surface receptors that phosphorylate Smad1/5/8 at the C-terminus. In addition to this BMP-activated…”
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Phosphorylation of Mad controls competition between wingless and BMP signaling
Published in Science signaling (11-10-2011)“…Bone morphogenetic proteins (BMPs) and Wnts are growth factors that provide essential patterning signals for cell proliferation and differentiation. Here, we…”
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Mad is required for wingless signaling in wing development and segment patterning in Drosophila
Published in PloS one (06-08-2009)“…A key question in developmental biology is how growth factor signals are integrated to generate pattern. In this study we investigated the integration of the…”
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Drosophila Smad2 opposes Mad signaling during wing vein development
Published in PloS one (28-04-2010)“…In the vertebrates, the BMP/Smad1 and TGF-beta/Smad2 signaling pathways execute antagonistic functions in different contexts of development. The…”
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Corrigendum: Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling
Published in Scientific reports (22-12-2017)“…This corrects the article DOI: 10.1038/srep32269…”
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Correction: Corrigendum: Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling
Published in Scientific reports (22-12-2017)“…Scientific Reports 6: Article number: 32269; published online: 31 August 2016; updated: 22 December 2017. This Article contains errors in Figure 4, where the…”
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Drosophila Smad2 degradation occurs independently of linker phosphorylations
Published in microPublication biology (2024)“…TGF-β signals are important for proliferation, differentiation, and cell fate determination during embryonic development and tissue homeostasis in adults…”
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Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues
Published in Scientific reports (07-11-2014)“…The BMP ligand Dpp, operates as a long range morphogen to control many important functions during Drosophila development from tissue patterning to growth. The…”
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Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad
Published in Cytokine & growth factor reviews (01-10-2009)“…Abstract BMPs pattern the dorsal–ventral axis of vertebrate embryos. Smad1/5/8 transduces the BMP signal, and receives phosphorylation inputs from both MAPK…”
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Integrating cell–cell signals: Duration of the Smad1/BMP signal is regulated by GSK3 and MAPK phosphorylations
Published in Developmental biology (01-06-2007)Get full text
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Assessment of epithelial innate antimicrobial factors in sinus tissue from patients with and without chronic rhinosinusitis
Published in International forum of allergy & rhinology (01-11-2014)“…Background Airway secretions contain endogenous antimicrobial factors (AMFs) that contribute to the innate host defense of the respiratory tract. Antibacterial…”
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Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo
Published in The International journal of developmental biology (01-12-2004)“…The insulin-like growth factor (IGF) signalling pathway has been highly conserved in animal evolution and, in mammals and Xenopus, plays a key role in…”
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WITHDRAWN: Self-regulation of embryonic pattern in Xenopus embryos
Published in Developmental biology (01-04-2007)Get full text
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Self-regulation of embryonic pattern in Xenopus embryos
Published in Developmental biology (01-06-2007)Get full text
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Mannose 6-phosphate receptors in an ancient vertebrate, zebrafish
Published in Development genes and evolution (01-03-2006)“…The endosome/lysosome system plays key roles in embryonic development, but difficulties posed by inaccessible mammalian embryos have hampered detailed studies…”
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