Search Results - "Eitzen, Gary"

Cdc42 regulates cytokine expression and trafficking in bronchial epithelial cells by Shouib, Rowayna, Eitzen, Gary

“…Airway epithelial cells can respond to incoming pathogens, allergens and stimulants through the secretion of cytokines and chemokines. These pro-inflammatory…”
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Mast cell granule motility and exocytosis is driven by dynamic microtubule formation and kinesin-1 motor function by Ibanga, Jeremies, Zhang, Eric L, Eitzen, Gary, Guo, Yitian

“…Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen…”
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Granule protein processing and regulated secretion in neutrophils by Sheshachalam, Avinash, Srivastava, Nutan, Mitchell, Troy, Lacy, Paige, Eitzen, Gary

“…Neutrophils are part of a family of granulocytes that, together with eosinophils and basophils, play an essential role in innate immunity. Neutrophils are the…”
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GEF-H1 Transduces FcεRI Signaling in Mast Cells to Activate RhoA and Focal Adhesion Formation during Exocytosis by Guo, Yitian, Negre, Judeah, Eitzen, Gary

“…When antigen-stimulated, mast cells release preformed inflammatory mediators stored in cytoplasmic granules. This occurs via a robust exocytosis mechanism…”
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Natamycin Inhibits Vacuole Fusion at the Priming Phase via a Specific Interaction with Ergosterol by TE WELSCHER, Yvonne Maria, JONES, Lynden, VAN LEEUWEN, Martin Richard, DIJKSTERHUIS, Jan, DE KRUIJFF, Ben, EITZEN, Gary, BREUKINK, Eefjan

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Peroxisomal Membrane Protein Inp2p Is the Peroxisome-Specific Receptor for the Myosin V Motor Myo2p of Saccharomyces cerevisiae by Fagarasanu, Andrei, Fagarasanu, Monica, Eitzen, Gary A., Aitchison, John D., Rachubinski, Richard A.

“…The faithful inheritance of organelles by daughter cells is essential to maintain the benefits afforded to eukaryotic cells by compartmentalization of…”
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Primary granule exocytosis in human neutrophils is regulated by Rac-dependent actin remodeling by Mitchell, Troy, Lo, Andrea, Logan, Michael R, Lacy, Paige, Eitzen, Gary

“…The actin cytoskeleton regulates exocytosis in all secretory cells. In neutrophils, Rac2 GTPase has been shown to control primary (azurophilic) granule…”
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A Small Molecule Inhibitor of Pex3–Pex19 Interaction Disrupts Glycosome Biogenesis and Causes Lethality in Trypanosoma brucei by Banerjee, Hiren, LaPointe, Paul, Eitzen, Gary, Rachubinski, Richard A.

“…Trypanosomatid parasites, including Trypanosoma and Leishmania , are infectious zoonotic agents for a number of severe diseases such as African sleeping…”
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Myosin-driven peroxisome partitioning in S. cerevisiae by Fagarasanu, Andrei, Mast, Fred D, Knoblach, Barbara, Jin, Yui, Brunner, Matthew J, Logan, Michael R, Glover, J.N. Mark, Eitzen, Gary A, Aitchison, John D, Weisman, Lois S, Rachubinski, Richard A

“…In Saccharomyces cerevisiae, the class V myosin motor Myo2p propels the movement of most organelles. We recently identified Inp2p as the peroxisome-specific…”
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A Ypt/Rab Effector Complex Containing the Sec1 Homolog Vps33p Is Required for Homotypic Vacuole Fusion by Seals, Darren F., Eitzen, Gary, Margolis, Nathan, Wickner, William T., Price, Albert

“…Yeast vacuoles undergo priming, docking, and homotypic fusion, although little has been known of the connections between these reactions. Vacuole-associated…”
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Remodeling of Organelle-Bound Actin Is Required for Yeast Vacuole Fusion by Eitzen, Gary, Wang, Li, Thorngren, Naomi, Wickner, William

“…Actin participates in several intracellular trafficking pathways. We now find that actin, bound to the surface of purified yeast vacuoles in the absence of…”
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Pex3 Peroxisome Biogenesis Proteins Function in Peroxisome Inheritance as Class V Myosin Receptors by Chang, Jinlan, Mast, Fred D., Fagarasanu, Andrei, Rachubinski, Dorian A., Eitzen, Gary A., Dacks, Joel B., Rachubinski, Richard A.

“…In Saccharomyces cerevisiae, peroxisomal inheritance from mother cell to bud is conducted by the class V myosin motor, Myo2p. However, homologues of S…”
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The Nitric Oxide Donor, S-Nitrosoglutathione, Rescues Peroxisome Number and Activity Defects in PEX1G843D Mild Zellweger Syndrome Fibroblasts by Liu, Yidi, Weaver, Ceileigh M., Sen, Yarina, Eitzen, Gary, Simmonds, Andrew J., Linchieh, Lilliana, Lurette, Olivier, Hebert-Chatelain, Etienne, Rachubinski, Richard A., Di Cara, Francesca

“…Peroxisome biogenesis disorders (PBDs) are a group of metabolic developmental diseases caused by mutations in one or more genes encoding peroxisomal proteins…”
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Cdc42p Is Activated during Vacuole Membrane Fusion in a Sterol-dependent Subreaction of Priming by Jones, Lynden, Tedrick, Kelly, Baier, Alicia, Logan, Michael R., Eitzen, Gary

“…Cdc42p is a Rho GTPase that initiates signaling cascades at spatially defined intracellular sites for many cellular functions. We have previously shown that…”
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Genomic analysis of homotypic vacuole fusion by Seeley, E Scott, Kato, Masashi, Margolis, Nathan, Wickner, William, Eitzen, Gary

“…Yeast vacuoles undergo fission and homotypic fusion, yielding one to three vacuoles per cell at steady state. Defects in vacuole fusion result in vacuole…”
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Inflammatory gene regulation by Cdc42 in airway epithelial cells by Shouib, Rowayna, Eitzen, Gary

“…Cytokine release from airway epithelial cells is a key immunological process that coordinates an immune response in the lungs. We propose that the Rho GTPase,…”
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Stimulation of Actin Polymerization by Vacuoles via Cdc42p-dependent Signaling by Isgandarova, Sabina, Jones, Lynden, Forsberg, Daniel, Loncar, Ana, Dawson, John, Tedrick, Kelly, Eitzen, Gary

“…We have previously shown that actin ligands inhibit the fusion of yeast vacuoles in vitro, which suggests that actin remodeling is a subreaction of membrane…”
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The Dynamin-like Protein Vps1p of the Yeast Saccharomyces cerevisiae Associates with Peroxisomes in a Pex19p-dependent Manner by Vizeacoumar, Franco J., Vreden, Wanda N., Fagarasanu, Monica, Eitzen, Gary A., Aitchison, John D., Rachubinski, Richard A.

“…Dynamins and dynamin-like proteins play important roles in organelle division. In Saccharomyces cerevisiae, the dynamin-like protein Vps1p (vacuolar protein…”
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Proteomic analysis of secretagogue-stimulated neutrophils implicates a role for actin and actin-interacting proteins in Rac2-mediated granule exocytosis by Eitzen, Gary, Lo, Andrea N, Mitchell, Troy, Kim, John D, Chao, Danny V, Lacy, Paige

“…Neutrophils are abundant leukocytes that play a primary role in defence against pathogens. Neutrophils enter sites of infection where they eliminate pathogens…”
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Enlarged peroxisomes are present in oleic acid-grown Yarrowia lipolytica overexpressing the PEX16 gene encoding an intraperoxisomal peripheral membrane peroxin by Eitzen, G.A. (University of Alberta, Edmonton, Canada.), Szilard, R.K, Rachubinski, R.A

“…Pex mutants of the yeast Yarrowia lipolytica are defective in peroxisome assembly. The mutant strain pex16-1 lacks morphologically recognizable peroxisomes…”
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