Search Results - "Eisfeld, Hannah S."
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Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
Published in Viruses (15-10-2021)“…Infections with viral pathogens are widespread and can cause a variety of different diseases. In-depth knowledge about viral triggers initiating an immune…”
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Journal Article -
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Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
Published in Cell death discovery (30-10-2021)“…Necrotic cell death represents a major pathogenic mechanism of Mycobacterium tuberculosis ( Mtb ) infection. It is increasingly evident that Mtb induces…”
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Journal Article -
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Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19
Published in EMBO molecular medicine (09-08-2021)“…Innate immunity triggers responsible for viral control or hyperinflammation in COVID‐19 are largely unknown. Here we show that the SARS‐CoV‐2 spike protein…”
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Journal Article