Search Results - "Eisenhauer, Philip"

Bone Marrow‐Derived Mesenchymal Stromal Cells Inhibit Th2‐Mediated Allergic Airways Inflammation in Mice by Goodwin, Meagan, Sueblinvong, Viranuj, Eisenhauer, Philip, Ziats, Nicholas P., LeClair, Laurie, Poynter, Matthew E., Steele, Chad, Rincon, Mercedes, Weiss, Daniel J.

“…Bone marrow‐derived mesenchymal stromal cells (BMSCs) mitigate inflammation in mouse models of acute lung injury. However, specific mechanisms of BMSC actions…”
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A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR) by King, Benjamin R, Hershkowitz, Dylan, Eisenhauer, Philip L, Weir, Marion E, Ziegler, Christopher M, Russo, Joanne, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Arenaviruses are enveloped negative-strand RNA viruses that cause significant human disease. These viruses encode only four proteins to accomplish the viral…”
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Visualization of Arenavirus RNA Species in Individual Cells by Single-Molecule Fluorescence In Situ Hybridization Suggests a Model of Cyclical Infection and Clearance during Persistence by King, Benjamin R, Samacoits, Aubin, Eisenhauer, Philip L, Ziegler, Christopher M, Bruce, Emily A, Zenklusen, Daniel, Zimmer, Christophe, Mueller, Florian, Botten, Jason

“…Lymphocytic choriomeningitis mammarenavirus (LCMV) is an enveloped, negative-strand RNA virus that causes serious disease in humans but establishes an…”
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Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A by Burgess, Edward J, Hoyt, Laura R, Randall, Matthew J, Mank, Madeleine M, Bivona, 3rd, Joseph J, Eisenhauer, Philip L, Botten, Jason W, Ballif, Bryan A, Lam, Ying-Wai, Wargo, Matthew J, Boyson, Jonathan E, Ather, Jennifer L, Poynter, Matthew E

“…Studies comparing endogenous and recombinant serum amyloid A (SAA) have generated conflicting data on the proinflammatory function of these proteins. In…”
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NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z by Ziegler, Christopher M, Dang, Loan, Eisenhauer, Philip, Kelly, Jamie A, King, Benjamin R, Klaus, Joseph P, Manuelyan, Inessa, Mattice, Ethan B, Shirley, David J, Weir, Marion E, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission…”
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Derivation of Lung Epithelium from Human Cord Blood-derived Mesenchymal Stem Cells by Sueblinvong, Viranuj, Loi, Roberto, Eisenhauer, Philip L, Bernstein, Ira M, Suratt, Benjamin T, Spees, Jeffrey L, Weiss, Daniel J

“…Recent studies have suggested that both embryonic stem cells and adult bone marrow stem cells can participate in the regeneration and repair of diseased adult…”
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Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle pre-assembly by King, Benjamin R, Kellner, Samuel, Eisenhauer, Philip L, Bruce, Emily A, Ziegler, Christopher M, Zenklusen, Daniel, Botten, Jason William

“…We report a fluorescence hybridization (FISH) assay that allows the visualization of lymphocytic choriomeningitis mammarenavirus (LCMV) genomic RNAs in…”
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A novel phosphoserine motif in the LCMV matrix protein Z regulates the release of infectious virus and defective interfering particles by Ziegler, Christopher M, Eisenhauer, Philip, Bruce, Emily A, Beganovic, Vedran, King, Benjamin R, Weir, Marion E, Ballif, Bryan A, Botten, Jason

“…We report that the lymphocytic choriomeningitis virus (LCMV) matrix protein, which drives viral budding, is phosphorylated at serine 41 (S41). A recombinant…”
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An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV by Guo, Hailong, Cho, Bomsoo, Hinton, Paul R, He, Sijia, Yu, Yongjun, Ramesh, Ashwin Kumar, Sivaccumar, Jwala Priyadarsini, Ku, Zhiqiang, Campo, Kristen, Holland, Sarah, Sachdeva, Sameer, Mensch, Christopher, Dawod, Mohamed, Whitaker, Annalis, Eisenhauer, Philip, Falcone, Allison, Honce, Rebekah, Botten, Jason W, Carroll, Stephen F, Keyt, Bruce A, Womack, Andrew W, Strohl, William R, Xu, Kai, Zhang, Ningyan, An, Zhiqiang, Ha, Sha, Shiver, John W, Fu, Tong-Ming

“…The capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they…”
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The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles by Ziegler, Christopher M, Eisenhauer, Philip, Bruce, Emily A, Weir, Marion E, King, Benjamin R, Klaus, Joseph P, Krementsov, Dimitry N, Shirley, David J, Ballif, Bryan A, Botten, Jason

“…Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high…”
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Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti- Andes orthohantavirus Neutralizing Antibodies in Patient Samples by Vial, Cecilia, Whitaker, Annalis, Wilhelm, Jan, Ovalle, Jimena, Perez, Ruth, Valdivieso, Francisca, Ferres, Marcela, Martinez-Valdebenito, Constanza, Eisenhauer, Philip, Mertz, Gregory J, Hooper, Jay W, Botten, Jason W, Vial, Pablo A

“…(ANDV) is the etiologic agent of hantavirus cardiopulmonary syndrome (HCPS), which has a case fatality rate around 35%, with no effective treatment or vaccine…”
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Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein by Ziegler, Christopher M, Eisenhauer, Philip, Manuelyan, Inessa, Weir, Marion E, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Lassa mammarenavirus (LASV) is an enveloped RNA virus that can cause Lassa fever, an acute hemorrhagic fever syndrome associated with significant morbidity and…”
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A Proteomics Survey of Junín Virus Interactions with Human Proteins Reveals Host Factors Required for Arenavirus Replication by Ziegler, Christopher M, Eisenhauer, Philip, Kelly, Jamie A, Dang, Loan N, Beganovic, Vedran, Bruce, Emily A, King, Benjamin R, Shirley, David J, Weir, Marion E, Ballif, Bryan A, Botten, Jason

“…Arenaviruses are negative-strand, enveloped RNA viruses that cause significant human disease. In particular, Junín mammarenavirus (JUNV) is the etiologic agent…”
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The Intracellular Cargo Receptor ERGIC-53 Is Required for the Production of Infectious Arenavirus, Coronavirus, and Filovirus Particles by Klaus, Joseph P., Eisenhauer, Philip, Russo, Joanne, Mason, Anne B., Do, Danh, King, Benjamin, Taatjes, Douglas, Cornillez-Ty, Cromwell, Boyson, Jonathan E., Thali, Markus, Zheng, Chunlei, Liao, Lujian, Yates, John R., Zhang, Bin, Ballif, Bryan A., Botten, Jason W.

“…Arenaviruses and hantaviruses cause severe human disease. Little is known regarding host proteins required for their propagation. We identified human proteins…”
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Chronic Exposure to Arsenic in the Drinking Water Alters the Expression of Immune Response Genes in Mouse Lung by Kozul, Courtney D., Hampton, Thomas H., Davey, Jennifer C., Gosse, Julie A., Nomikos, Athena P., Eisenhauer, Phillip L., Weiss, Daniel J., Thorpe, Jessica E., Ihnat, Michael A., Hamilton, Joshua W.

“…Background: Chronic exposure to drinking water arsenic is a significant worldwide environmental health concern. Exposure to As is associated with an increased…”
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Endogenous Distal Airway Progenitor Cells, Lung Mechanics, and Disproportionate Lobar Growth Following Long‐Term Postpneumonectomy in Mice by Eisenhauer, Philip, Earle, Benjamin, Loi, Roberto, Sueblinvong, Viranuj, Goodwin, Meagan, Allen, Gilman B., Lundblad, Lennart, Mazan, Melissa R., Hoffman, Andrew M., Weiss, Daniel J.

“…Using a model of postpneumonectomy (PNY) compensatory lung growth in mice, we previously observed an increase in numbers of a putative endogenous distal airway…”
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Stimulation of B Cell Immunity in Flavivirus-Naive Individuals by the Tetravalent Live Attenuated Dengue Vaccine TV003 by Tu, Huy A., Nivarthi, Usha K., Graham, Nancy R., Eisenhauer, Philip, Delacruz, Matthew J., Pierce, Kristen K., Whitehead, Stephen S., Boyson, Jonathan E., Botten, Jason W., Kirkpatrick, Beth D., Durbin, Anna P., deSilva, Aravinda M., Diehl, Sean A.

“…The tetravalent live attenuated dengue vaccine candidate TV003 induces neutralizing antibodies against all four dengue virus serotypes (DENV1–DENV4) and…”
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Endogenous Distal Airway Progenitor Cells, Lung Mechanics, and Disproportionate Lobar Growth following Long-Term Post-Pneumonectomy in Mice by Eisenhauer, Philip, Earle, Benjamin, Loi, Roberto, Sueblinvong, Viranuj, Goodwin, Meagan, Allen, Gilman B., Lundblad, Lennart, Mazan, Melissa R., Hoffman, Andrew M., Weiss, Daniel J.

“…Utilizing a model of post-pneumonectomy (PNY) compensatory lung growth in mice, we previously observed an increase in numbers of a putative endogenous distal…”
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