Search Results - "Eisenberg, S P"
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Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro
Published in The Journal of clinical investigation (01-07-1995)“…Infection of adherent primary monocytes with HIV-1Ba-L is significantly suppressed in the presence of human saliva. By reverse transcriptase (RT) levels,…”
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2
Interleukin 1 Receptor Antagonist is a Member of the Interleukin 1 Gene Family: Evolution of a Cytokine Control Mechanism
Published in Proceedings of the National Academy of Sciences - PNAS (15-06-1991)“…Interleukin 1 receptor antagonist (IL-1ra) is a protein that binds to the IL-1 receptor and blocks the binding of both IL-1α and -β without inducing a signal…”
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3
Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction
Published in The Journal of biological chemistry (05-06-1991)“…The interleukin-1 receptor antagonist (IL-1ra) is a protein capable of inhibiting receptor binding and biological activities of IL-1 without inducing an…”
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4
Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist
Published in The Journal of clinical investigation (01-05-1990)“…Human monocytes cultured on adherent IgG produce a specific IL-1 inhibitor that functions as a receptor antagonist (IL-1ra). This molecular has been purified,…”
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5
Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis
Published in The Journal of clinical investigation (01-07-1994)“…Administration of exogenous interleukin-1 receptor antagonist (IL-1ra) is effective in reducing the severity of disease in animal models of acute inflammation…”
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Location of the protease-inhibitory region of secretory leukocyte protease inhibitor
Published in The Journal of biological chemistry (15-05-1990)“…Secretory leukocyte protease inhibitor (SLPI) is a two-domain protein that inhibits a wide range of proteases including chymotrypsin, leukocyte elastase, and…”
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The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1- induced acute inflammation
Published in The American journal of pathology (01-03-1991)“…Endotoxin, a lipopolysaccharide (LPS) component of gram-negative bacteria, induces alveolar macrophages to express interleukin-1 (IL-1). Lipopolysaccharide and…”
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Intratracheal administration of endotoxin and cytokines. IV. The soluble tumor necrosis factor receptor type I inhibits acute inflammation
Published in The American journal of pathology (01-05-1993)“…Endotoxin lipopolysaccharide (LPS) administered intratracheally to rats causes pulmonary tumor necrosis factor alpha (TNF) and interleukin-1 (IL-1) production…”
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Conversion of the Interleukin 1 Receptor Antagonist into an Agonist by Site-Specific Mutagenesis
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1991)“…Interleukin 1 (IL-1) receptor antagonist (IL-1ra) is a naturally occurring protein that binds to the IL-1 receptor present on T cells, fibroblasts, and other…”
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Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription
Published in Blood (01-08-1997)“…Infection of monocytes with human immunodeficiency virus type 1(Ba-L) (HIV-1(Ba-L)) is significantly inhibited by treatment with the serine protease inhibitor,…”
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11
X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution
Published in The Journal of biological chemistry (29-04-1994)“…Interleukin-1 receptor antagonist (IL-1ra) is a natural competitive antagonist of IL-1. In order to further elucidate the mechanism by which IL-1ra binds…”
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12
Production and characterization of human basic fibroblast growth factor from Escherichia coli
Published in The Journal of biological chemistry (05-11-1988)“…The cDNA sequence coding for human basic fibroblast growth factor (bFGF) has been cloned downstream of a transcription promoter recognized by the bacteriophage…”
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13
Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation
Published in The Journal of biological chemistry (04-03-1994)“…Genomic and cDNA clones for rabbit interleukin-1 receptor antagonist (IL-1ra) were isolate based on homology with the human, mouse, and rat IL-1ra gene. A…”
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Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation
Published in The American journal of pathology (01-07-1992)“…After the intravenous (IV) injection of endotoxin, (lipopolysaccharide [LPS]), in the rat, interleukin-1 alpha/beta (IL-1 alpha/beta) mRNA expression peaks at…”
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15
Interleukin-1 receptor antagonist binds to the type II interleukin-1 receptor on B cells and neutrophils
Published in The Journal of biological chemistry (25-10-1991)“…We have examined the binding of human and rodent interleukin-1 receptor antagonist (IL-1ra) to the type II IL-1 receptor on the human B cell line, Raji, on the…”
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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
Published in The Journal of biological chemistry (06-04-2001)“…We have mapped conserved regions of enhanced DNase I accessibility within the endogenous chromosomal locus of vascular endothelial growth factor A (VEGF-A)…”
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An interleukin 1 beta point mutant demonstrates that jun/fos expression is not sufficient for fibroblast metalloproteinase expression
Published in The Journal of biological chemistry (05-09-1991)“…Substitution of glycine for arginine at position 127 of the mature human interleukin 1 beta protein generates a mutant IL-1 beta protein (IL-1 beta R---G)…”
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Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes
Published in Molecular and Cellular Biology (01-08-1985)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Interleukin-1β induces interleukin-1 receptor antagonist and tumor necrosis factor binding protein in humans
Published in Cancer research (Chicago, Ill.) (01-09-1993)“…Sustained release or high levels of interleukin-1 (IL-1) and/or tumor necrosis factor (TNF), as observed after endotoxin challenge, can produce a variety of…”
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Secretory leukocyte protease inhibitor binding to mRNA and DNA as a possible cause of toxicity to Escherichia coli
Published in Journal of Bacteriology (01-04-1989)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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