Search Results - "Eisenberg, Marcia"

Bacteriophage-Based Detection of Staphylococcus aureus in Human Serum by Brown, Matthew, Hall, Alex, Zahn, Henriett, Eisenberg, Marcia, Erickson, Stephen

“…Bacteriophages have been investigated for clinical utility, both as diagnostic tools and as therapeutic interventions. In order to be applied successfully, a…”
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Tailoring the Host Range of Ackermannviridae Bacteriophages through Chimeric Tailspike Proteins by Gil, Jose, Paulson, John, Brown, Matthew, Zahn, Henriett, Nguyen, Minh M, Eisenberg, Marcia, Erickson, Stephen

“…Host range is a major determinant in the industrial utility of a bacteriophage. A model host range permits broad recognition across serovars of a target…”
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Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden by Morrison, Carl, Pabla, Sarabjot, Conroy, Jeffrey M, Nesline, Mary K, Glenn, Sean T, Dressman, Devin, Papanicolau-Sengos, Antonios, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Qin, Moachun, Wang, Yirong, Lenzo, Felicia L, Omilian, Angela, Bshara, Wiam, Zibelman, Matthew, Ghatalia, Pooja, Dragnev, Konstantin, Shirai, Keisuke, Madden, Katherine G, Tafe, Laura J, Shah, Neel, Kasuganti, Deepa, de la Cruz-Merino, Luis, Araujo, Isabel, Saenger, Yvonne, Bogardus, Margaret, Villalona-Calero, Miguel, Diaz, Zuanel, Day, Roger, Eisenberg, Marcia, Anderson, Steven M, Puzanov, Igor, Galluzzi, Lorenzo, Gardner, Mark, Ernstoff, Marc S

“…Immune checkpoint inhibitors (ICIs) have changed the clinical management of melanoma. However, not all patients respond, and current biomarkers including PD-L1…”
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A program for real-time surveillance of SARS-CoV-2 genetics by Brochu, Hayden N., Song, Kuncheng, Zhang, Qimin, Zeng, Qiandong, Shafi, Adib, Robinson, Matthew, Humphrey, Jake, Croy, Bobbi, Peavy, Lydia, Perera, Minoli, Parker, Scott, Pruitt, John, Munroe, Jason, Ghatti, Rama, Urban, Thomas J., Harris, Ayla B., Alfego, David, Norvell, Brian, Levandoski, Michael, Krueger, Brian, Williams, Jonathan D., Boles, Deborah, Nye, Melinda B., Dale, Suzanne E., Sapeta, Michael, Petropoulos, Christos J., Meltzer, Jonathan, Eisenberg, Marcia, Cohen, Oren, Letovsky, Stanley, Iyer, Lakshmanan K.

“…The COVID-19 pandemic brought forth an urgent need for widespread genomic surveillance for rapid detection and monitoring of emerging SARS-CoV-2 variants. It…”
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Isolation and engineering of a Listeria grayi bacteriophage by Erickson, Stephen, Paulson, John, Brown, Matthew, Hahn, Wendy, Gil, Jose, Barron-Montenegro, Rocío, Moreno-Switt, Andrea I., Eisenberg, Marcia, Nguyen, Minh M.

“…The lack of bacteriophages capable of infecting the Listeria species, Listeria grayi , is academically intriguing and presents an obstacle to the development…”
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Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer by Seager, R J, Senosain, Maria-Fernanda, Van Roey, Erik, Gao, Shuang, DePietro, Paul, Nesline, Mary K, Dash, Durga Prasad, Zhang, Shengle, Ko, Heidi, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian J, Severson, Eric A, Ramkissoon, Shakti, Conroy, Jeffrey M, Pabla, Sarabjot

“…Cancer-testis antigens (CTAs) are tumor antigens that are normally expressed in the testes but are aberrantly expressed in several cancers. CTA overexpression…”
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Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer by Wallen, Zachary D, Ko, Heidi, Nesline, Mary K, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Pabla, Sarabjot, Conroy, Jeffrey, Jackson, Jennifer B, Saini, Kamal S, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Sathyan, Pratheesh, Severson, Eric A, Ramkissoon, Shakti H

“…Younger patients with non-small cell lung cancer (NSCLC) (<50 years) represent a significant patient population with distinct clinicopathological features and…”
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Development and Evaluation of a Sensitive Bacteriophage-Based MRSA Diagnostic Screen by Brown, Matthew, Hahn, Wendy, Bailey, Bryant, Hall, Alex, Rodriguez, Gema, Zahn, Henriett, Eisenberg, Marcia, Erickson, Stephen

“…Engineered luciferase reporter bacteriophages provide specific, sensitive, rapid and low-cost detection of target bacteria and address growing diagnostic needs…”
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Case report: Single gene testing and comprehensive genomic profiling in non-small cell lung cancer—a case series of divergent results from a large reference laboratory by Strickland, Kyle C., Nesline, Mary K., Previs, Rebecca A., Ko, Heidi, Cooper, Maureen, Rushton, Jennifer R., Wallen, Zachary D., Pabla, Sarabjot, Conroy, Jeffrey M., Sausen, Mark, Saini, Kamal S., Cantini, Luca, Jensen, Taylor J., Caveney, Brian J., Eisenberg, Marcia, Severson, Eric A., Ramkissoon, Shakti

“…Clinical management of non-small cell lung cancer (NSCLC) requires accurate identification of tumor-specific genetic alterations to inform treatment options…”
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Is HER2-Low a New Clinical Entity or Merely a Biomarker for an Antibody Drug Conjugate? by Ko, Heidi, Previs, Rebecca A., Strickland, Kyle C., Klein, Jonathan, Caveney, Brian, Chiruzzi, Chiara, Eisenberg, Marcia, Severson, Eric A., Ramkissoon, Shakti, Saini, Kamal S.

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1455 Characterization of gene expression signatures of tumor immunogenicity and cellular proliferation from murine cancer models grown in vitro and in vivo by Strickland, Kyle C, Barnes, Sheri, Wallen, Zachary D, Nesline, Mary K, Jensen, Taylor J, Caveney, Brian, Eisenberg, Marcia, Reddy, Prasanth, Severson, Eric A, Wise, Scott C, Ramkissoon, Shakti

“…BackgroundTumor immunogenicity and cellular proliferation are critical factors influencing cancer progression and response to therapy. The precise way these…”
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The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer by Nesline, Mary K., Subbiah, Vivek, Previs, Rebecca A., Strickland, Kyle C., Ko, Heidi, DePietro, Paul, Biorn, Michael D., Cooper, Maureen, Wu, Nini, Conroy, Jeffrey, Pabla, Sarabjot, Zhang, Shengle, Wallen, Zachary D., Sathyan, Pratheesh, Saini, Kamal, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A., Ramkissoon, Shakti

“…Introduction Tissue-based broad molecular profiling of guideline-recommended biomarkers is advised for the therapeutic management of patients with non-small…”
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1499 Molecular and immune profiling of lobular-enriched versus non-lobular invasive breast cancers by Strickland, Kyle C, Pabla, Sarabjot, Ko, Heidi, Previs, Rebecca A, Wallen, Zachary D, Nesline, Mary K, Zhang, Shengle, Conroy, Jeffrey M, Jackson, Jennifer B, Saini, Kamal S, Jensen, Taylor J, Caveney, Brian, Eisenberg, Marcia, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

“…BackgroundInvasive lobular carcinoma (ILC) is a morphologically distinct endocrine-sensitive sub-type of invasive breast cancer. Invasive ductal carcinoma has…”
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O09: Potential germline variants are frequently identified when performing comprehensive genomic profiling of solid tumors by Jensen, Taylor, Noeth, Dagny, Cronister, Amy, DePietro, Paul, Klein, Roger, Nesline, Mary, Pabla, Sarabjot, Chenn, Anjen, Zhang, Shengle, Klein, Jonathan, Howarth, Sarah, Severson, Eric, Ramkissoon, Shakti, Eisenberg, Marcia, Reddy, Prasanth, Conroy, Jeffrey

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SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes by Kaufman, Harvey W, Letovsky, Stanley, Meyer, 3rd, William A, Gillim, Laura, Assimon, Magdalene M, Kabelac, Carly A, Kroner, John W, Reynolds, Shannon L, Eisenberg, Marcia

“…In the absence of evidence of clinical utility, the United States' Centers for Disease Control and Prevention does not currently recommend the assessment of…”
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175 Metastatic triple negative breast cancer has distinct tumor immune landscape by Seager, Robert, Ko, Heidi, Pabla, Sarabjot, Senosain, Maria-Fernanda, Roey, Erik Van, Gao, Shuang, Strickland, Kyle C, Previs, Rebecca A, Nesline, Mary K, Hastings, Stephanie B, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A, Ramkissoon, Shakti, Gandhi, Shipra

“…BackgroundTriple negative breast cancer (TNBC) is considered the most immunogenic breast cancer subtype due to higher levels of tumor infiltrating immune cells…”
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184 Distinct immunotherapy immune response phenotypes in non-small cell lung cancer present with unique genomic alteration profiles by Wallen, Zachary D, Seager, RJ, Pabla, Sarabjot, Nesline, Mary K, Roey, Erik Van, Gao, Shuang, Senosain, Maria-Fernanda, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

“…BackgroundBiomarkers for predicting response to immune checkpoint inhibitors (ICPIs) in non-small cell lung cancer (NSCLC) are currently limited to PD-1/PD-L1…”
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513 Comprehensive genomic and immune profiling of ALK fusion-positive and negative lung adenocarcinomas by Strickland, Kyle C, Wallen, Zachary D, Pabla, Sarabjot, Ko, Heidi, Nesline, Mary K, Previs, Rebecca A, Zhang, Shengle, Conroy, Jeffrey M, Sathyan, Pratheesh, Saini, Kamal S, Jensen, Taylor J, Caveney, Brian, Eisenberg, Marcia, Reddy, Prasanth, Muskavitch, Marc AT, Culver, Ken, Severson, Eric A, Ramkissoon, Shakti

“…Background ALK rearrangements are known drivers of a subset of lung adenocarcinomas (LAs), and ALK fusion-positive tumors are associated with reduced efficacy…”
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176 Immune microenvironment of primary versus metastatic melanoma of the brain by Senosain, Maria-Fernanda, Ko, Heidi, Pabla, Sarabjot, Seager, Robert, Roey, Erik Van, Gao, Shuang, Strickland, Kyle C, Previs, Rebecca A, Nesline, Mary K, Hastings, Stephanie B, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A, Ramkissoon, Shakti

“…BackgroundImmune checkpoint inhibitors (ICIs) have revolutionized the treatment of melanoma resulting in improved clinical outcomes, however approximately 50%…”
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Multicenter Experience with Upper Gastrointestinal Polyps in Pediatric Patients with Familial Adenomatous Polyposis by ATTARD, Thomas M, CUFFARI, Carmen, TAJOURI, Tanya, STONER, Julie A, EISENBERG, Marcia T, YARDLEY, John H, ABRAHAM, Susan C, PERRY, Deborah, VANDERHOOF, Jon, LYNCH, Henry

“…Familial adenomatous polyposis (FAP) is a hereditary cancer syndrome that includes gastro-duodenal involvement, polyposis, and a propensity to adenocarcinoma…”
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