Search Results - "Eisele, Leslie"
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Mycobacterium tuberculosis Rv3586 (DacA) is a diadenylate cyclase that converts ATP or ADP into c-di-AMP
Published in PloS one (17-04-2012)“…Cyclic diguanosine monophosphate (c-di-GMP) and cyclic diadenosine monophosphate (c-di-AMP) are recently identified signaling molecules. c-di-GMP has been…”
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2
Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence
Published in Journal of Bacteriology (01-11-2013)“…Cyclic di-AMP (c-di-AMP) and cyclic di-GMP (c-di-GMP) are signaling molecules that play important roles in bacterial biology and pathogenesis. However, these…”
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3
Mycobacterial phosphodiesterase Rv0805 is a virulence determinant and its cyclic nucleotide hydrolytic activity is required for propionate detoxification
Published in Molecular microbiology (01-04-2023)“…Cyclic AMP (cAMP) signaling is essential to Mycobacterium tuberculosis (Mtb) pathogenesis. However, the roles of phosphodiesterases (PDEs) Rv0805, and the…”
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4
Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB)
Published in PloS one (11-06-2014)“…Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because…”
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5
Specificity of Human Thymine DNA Glycosylase Depends on N-Glycosidic Bond Stability
Published in Journal of the American Chemical Society (27-09-2006)“…Initiating the DNA base excision repair pathway, DNA glycosylases find and hydrolytically excise damaged bases from DNA. While some DNA glycosylases exhibit…”
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6
Hydrophobic and charged residues in the C-terminal arm of hepatitis C virus RNA-dependent RNA polymerase regulate initiation and elongation
Published in Journal of virology (01-02-2015)“…The RNA-dependent RNA polymerase (RdRp) of hepatitis C virus (HCV) is essential for viral genome replication. Crystal structures of the HCV RdRp reveal two…”
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7
Conservation of Structure and Protein-Protein Interactions Mediated by the Secreted Mycobacterial Proteins EsxA, EsxB, and EspA
Published in Journal of Bacteriology (01-01-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin
Published in Biochemical pharmacology (15-12-2003)“…The aryl hydrocarbon receptor (AhR), when activated by exogenous ligands such as 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD), regulates expression of several…”
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9
Zinc Induces Dimerization of the Class II Major Histocompatibility Complex Molecule That Leads to Cooperative Binding to a Superantigen
Published in The Journal of biological chemistry (02-03-2007)“…Dimerization of class II major histocompatibility complex (MHC) plays an important role in the MHC biological function. Mycoplasma arthritidis-derived mitogen…”
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10
Allophycocyanin: Trimers, monomers, subunits, and homodimers
Published in Biopolymers (2003)“…Allophycocyanin is a photosynthetic light‐harvesting pigment–protein complex located in the phycobilisomes of cyanobacteria and red algae. Using dynamic light…”
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11
Characterization of Human γ-glutamyl hydrolase in solution demonstrates that the enzyme is a non-dissociating homodimer
Published in Biochimica et biophysica acta (01-09-2006)“…Human γ-glutamyl hydrolase (hGH) is a key enzyme in the metabolism of folic acid and in the pharmacology of many antifolate drugs. hGH catalyzes removal of the…”
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12
Fluorescence polarization studies on four biliproteins and a bilin model for phycoerythrin 545
Published in Biochimica et biophysica acta (04-08-1999)“…Fluorescence (excitation) polarization spectroscopy in the wavelength region of the bilin chromophores was applied to phycoerythrocyanin (CV-phycocyanin),…”
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13
Anti-prostate cancer and anti-breast cancer activities of two peptides derived from alpha-fetoprotein
Published in Anticancer research (01-09-2002)“…A chemically synthesized 34-amino-acid peptide and a select analog have been studied to determine their activities against the growth of prostate and breast…”
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14
Thermophilic C-phycocyanin: effect of temperature, monomer stability, and structure
Published in Biochimica et biophysica acta. Bioenergetics (22-08-1997)“…C-Phycocyanin has been purified from Synechococcus lividus (SyI), which grows between 66 and 73°C at the highest temperature of any cyanobacterium and of any…”
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15
Bilin Organization in Cryptomonad Biliproteins
Published in Biochemistry (Easton) (30-03-1999)“…The bilin organization of three cryptomonad biliproteins (phycocyanins 612 and 645 and phycoerythrin 545) was examined in detail. Two others (phycocyanin 630…”
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16
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation
Published in PloS one (21-05-2015)“…Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of…”
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17
Phycoerythrin 545: Monomers, Energy Migration, Bilin Topography, and Monomer/Dimer Equilibrium
Published in Biochemistry (Easton) (06-01-1998)“…Phycoerythrin 545 was isolated having an α2β2 (dimer) protein structure at pH 6.0 and 2 g/L protein concentration with eight bilin chromophores. Monomers (αβ)…”
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18
Studies on C-phycocyanin from Cyanidium caldarium, a eukaryote at the extremes of habitat
Published in Biochimica et biophysica acta (10-01-2000)“…C-Phycocyanin, a biliprotein, was purified from the red alga, Cyanidium caldarium. This alga grows at temperatures up to 57°C, a very high temperature for a…”
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19
Differential Neutralizing Activities of a Single Domain Camelid Antibody
Published in PloS one (11-06-2014)“…Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because…”
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20
Bilin Chromophores as Reporters of Unique Protein Conformations of Phycocyanin 645
Published in Biochemistry (Easton) (03-12-1996)“…At 45 °C, phycocyanin 645 maximally undergoes a reversible and stable conformational change. The change is observed in the visible (chromophore) region of the…”
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