Search Results - "Einarson, Thomas R."

Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017 by Einarson, Thomas R, Acs, Annabel, Ludwig, Craig, Panton, Ulrik H

“…Cardiovascular disease (CVD) is a common comorbidity in type 2 diabetes (T2DM). CVD's prevalence has been growing over time. To estimate the current prevalence…”
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Prevalence of Depression during pregnancy: Systematic review by BENNETT, Heather A, EINARSON, Adrienne, TADDIO, Anna, KOREN, Gideon, EINARSON, Thomas R

“…Current estimates of the prevalence of depression during pregnancy vary widely. A more precise estimate is required to identify the level of disease burden and…”
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Sensitivity of Patient Outcomes to Pharmacist Interventions. Part I: Systematic Review and Meta-Analysis in Diabetes Management by Machado, Marcio, Bajcar, Jana, Guzzo, Giovanni C, Einarson, Thomas R

“…Background: Pharmacists participate in managing diabetes therapy. Despite many reviews, few have quantified the impact of pharmacists' interventions…”
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Systematic Review and Meta-analysis of the Effect of Warming Local Anesthetics on Injection Pain by Hogan, Mary-Ellen, BScPhm, PharmD, vanderVaart, Sondra, MBA, PhD(c), Perampaladas, Kumar, BSc, MSc, Machado, Márcio, MSc, PhD, Einarson, Thomas R., MSc, PhD, Taddio, Anna, MSc, PhD

“…Study objective Local anesthetics are the main class of analgesics used for pain management during laceration repair and other minor surgeries; however, they…”
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The Safety of Proton Pump Inhibitors (PPIs) in Pregnancy: A Meta-Analysis by GILL, Simerpal K, O'BRIEN, Lisa, EINARSON, Thomas R, KOREN, Gideon

“…Heartburn and acid reflux are common medical disorders in pregnancy and can result in serious discomfort and complications. Furthermore, some pregnant women…”
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Dose escalation of biologics in Crohn's disease: critical review of observational studies by Einarson, Thomas R., Bereza, Basil G., Ying Lee, Xin, Lelli, Filippo

“…Background: Biologics used to treat Crohn's disease (CD) may lose their effect over time, requiring dose escalation. Little information is available on this…”
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Treatments for metastatic melanoma: Synthesis of evidence from randomized trials by Lui, Philip, Cashin, Richard, Machado, Márcio, Hemels, Michiel, Corey-Lisle, Patricia K, Einarson, Thomas R

“…Summary Background Advanced melanomas (non-resectable Stage-III/IV) are fatal, with few effective treatments. It remains unclear if other drugs offer…”
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Cost-benefit analysis of pharmacist interventions over 36 months in a university hospital by Cazarim, Maurilio de Souza, Rodrigues, João Paulo Vilela, Calcini, Priscila Santos, Einarson, Thomas, Pereira, Leonardo Régis Leira

“…OBJECTIVE: To perform a cost-benefits analysis of a clinical pharmacy (CP) service implemented in a Neurology ward of a tertiary teaching hospital. METHODS:…”
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Systematic review and quality assessment of economic evaluations and quality-of-life studies related to generalized anxiety disorder by Bereza, Basil G., CFA, Machado, Márcio, PhD, Einarson, Thomas R., PhD

“…Abstract Background: The objectives of this article were to systematically review, summarize the results of, and assess the quality of economic evaluations and…”
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Economic Burden of Cardiovascular Disease in Type 2 Diabetes: A Systematic Review by Einarson, Thomas R., Acs, Annabel, Ludwig, Craig, Panton, Ulrik H.

“…Cardiovascular diseases (CVDs) constitute major comorbidities in type 2 diabetes mellitus (T2DM), contributing substantially to treatment costs for T2DM. An…”
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Probiotic Safety in Pregnancy: A Systematic Review and Meta-analysis of Randomized Controlled Trials of Lactobacillus, Bifidobacterium, and Saccharomyces spp by Dugoua, Jean-Jacques, HBSc, ND, Machado, Marcio, PhD, Zhu, Xu, MSc, Chen, Xin, HBSc, Koren, Gideon, MD, FABMT, FRCPC, Einarson, Thomas R., PhD

“…Abstract Our objective in this study was to review systematically the evidence for safety of Lactobacillus, Bifidobacterium and Saccharomyces spp . during…”
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Health state utilities and quality of life in patients with hepatitis B by Woo, Gloria, Tomlinson, George, Yim, Colina, Lilly, Les, Therapondos, George, Wong, David K H, Ungar, Wendy J, Einarson, Thomas R, Sherman, Morris, Heathcote, Jenny E, Krahn, Murray

“…The effect of chronic hepatitis B (CHB) infection on health-related quality of life (HRQoL) and health state utilities has not been well characterized. To…”
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Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: Evidence from a meta-analysis by Iskedjian, Michael, Einarson, Thomas R., MacKeigan, Linda D., Shear, Neil, Addis, Antonio, Mittmann, Nicole, Ilersich, A.Lane

“…Background: Rates of patient adherence (compliance) to pharmacotherapy range from <5% to >90%. Negative determinants include multiple daily dosing (MDD),…”
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Quantifying the global rates of nausea and vomiting of pregnancy: a meta analysis by Einarson, Thomas R, Piwko, Charles, Koren, Gideon

“…Nausea and vomiting of pregnancy (NVP) is the most common medical condition in pregnancy, affecting women worldwide. It is unclear whether its prevalence and…”
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Rates of Spontaneous and Therapeutic Abortions Following Use of Antidepressants in Pregnancy: Results From a Large Prospective Database by Einarson, Adrienne, RN, Choi, Jacqueline, BSc, Einarson, Thomas R., PhD, Koren, Gideon, MD

“…Abstract Objective The use of antidepressants during pregnancy remains a controversial issue, and there is little information on the risk of spontaneous…”
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Relationship between blood glucose and carotid intima media thickness: A meta-analysis by Einarson, Thomas R, Hunchuck, Jonathan, Hemels, Michiel

“…Increased coronary intima media thickness (CIMT) has been associated with adverse cardiovascular outcomes, as have increased glucose levels. The link has not…”
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Nausea and vomiting of pregnancy (NVP) and depression: cause or effect? by Bozzo, Pina, Einarson, Thomas R, Koren, Gideon, Einarson, Adrienne

“…Both nausea and vomiting and depression are common conditions affecting women during pregnancy. Several studies have linked depression with nausea and vomiting…”
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Does Paroxetine Cause Cardiac Malformations? by O’Brien, Lisa, MSc, Einarson, Thomas R., PhD, Sarkar, Moumita, MSc, Einarson, Adrienne, RN, Koren, Gideon, MD

“…Abstract Background Debate has recently arisen about the safety of paroxetine use in pregnancy, prompted by reports of increased risks for cardiac defects…”
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Reference values for hair cotinine as a biomarker of active and passive smoking in women of reproductive age, pregnant women, children, and neonates : Systematic review and meta-analysis by FLORESCU, Ana, FERRENCE, Roberta, EINARSON, Thomas R, SELBY, Peter, KRAMER, Michael, WOODRUFF, Susan, GROSSMAN, Lindsey, RANKIN, Allison, JACQZ-AIGRAIN, Evelyn, KOREN, Gideon

“…Exposure to environmental tobacco smoke (ETS) is most often estimated using questionnaires, but they are unreliable. Biomarkers can provide valid information…”
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Increased use of antidepressants in Canada: 1981-2000 by Hemels, ME, Koren, G, Einarson, TR

“…OBJECTIVE: To provide a descriptive analysis of Canadian utilization (prescriptions, cost, cost per prescription) of antidepressants (ATC-code: N06A). METHODS:…”
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