Search Results - "Einarsdottir, K"
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A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy
Published in Blood (23-01-2014)“…Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia…”
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Decreasing Photoreactivity and Concurrent Change in Dissolved Organic Matter Composition With Increasing Inland Water Residence Time
Published in Global biogeochemical cycles (01-03-2024)“…Photochemical degradation of dissolved organic matter (DOM) has been the subject of numerous studies; however, its regulation along the inland water continuum…”
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The influence of pH on dissolved organic matter fluorescence in inland waters
Published in Analytical methods (31-03-2022)“…Fluorescence is an easily available analytical technique used to assess the optical characteristics of dissolved organic matter (DOM). Despite widespread use,…”
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Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice
Published in PloS one (19-05-2017)“…Current anti-cancer therapeutic antibodies that are used in the clinic are predominantly humanized or fully human immunoglobulin G1 (IgG1). These antibodies…”
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Transitional B Cells and TLR9 Responses Are Defective in Selective IgA Deficiency
Published in Frontiers in immunology (27-04-2018)“…Selective IgA deficiency (IgAD) is the most common primary antibody deficiency in the western world with affected individuals suffering from an increased…”
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Atomoxetine in Early Pregnancy and the Prevalence of Major Congenital Malformations: A Multinational Study
Published in The journal of clinical psychiatry (01-01-2023)“…Most research on safety of attention-deficit/hyperactivity disorder (ADHD) medications during pregnancy concerns central nervous system stimulants, while…”
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On the perplexingly low rate of transport of IgG2 across the human placenta
Published in PloS one (24-09-2014)“…The neonatal receptor, FcRn, mediates both serum half-life extension as well as active transport of maternal IgG to the fetus during pregnancy. Therefore,…”
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Mapping of Signaling Pathways Linked to sIgAD Reveals Impaired IL-21 Driven STAT3 B-Cell Activation
Published in Frontiers in immunology (18-03-2019)“…It has recently been shown that individuals with selective IgA deficiency (sIgAD) have defective B cell responses both to T cell dependent and independent…”
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Intranasal Administration of Antibody-Bound Respiratory Syncytial Virus Particles Efficiently Primes Virus-Specific Immune Responses in Mice
Published in Journal of Virology (01-07-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Risk Factors for Hormone Receptor-Defined Breast Cancer in Postmenopausal Women
Published in Cancer epidemiology, biomarkers & prevention (01-12-2006)“…The effect of classic breast cancer risk factors on hormone receptor-defined breast cancer is not fully clarified. We explored these associations in a Swedish…”
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IgG-effector functions: “The Good, The Bad and The Ugly”
Published in Immunology letters (01-08-2014)“…Highlights • FcγR polymorphisms affect binding to IgG and thereby strength of immune reactions. • Likewise, FcγR-IgG binding is affected by which IgG…”
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The multiple facets of FcRn in immunity
Published in Immunological reviews (01-11-2015)“…Summary The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in various tissues, providing newborns with humoral immunity, and for…”
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Smoking and a complement gene polymorphism interact in promoting cardiovascular disease morbidity and mortality
Published in Clinical and experimental immunology (01-07-2007)“…We have demonstrated previously that carriers of a genotype called C4B*Q0 (silent allele of the C4B gene) have a substantially increased risk to suffer from…”
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Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk
Published in PLoS medicine (01-06-2006)“…Checkpoint kinase 2 (CHEK2) averts cancer development by promoting cell cycle arrest and activating DNA repair in genetically damaged cells. Previous…”
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Warfarin anticoagulation intensity in specialist-based and in computer-assisted dosing practice
Published in International journal of laboratory hematology (01-10-2008)“…Summary The efficacy and safety of oral anticoagulation (OA) with vitamin K antagonists depends on maintaining anticoagulation intensity, measured as…”
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Resolution of Th/Tc17‐driven inflammation during anti‐TNFα treatment of rheumatoid arthritis reveals a unique immune biomarker profiling pattern
Published in Scandinavian journal of immunology (01-01-2022)“…Rheumatoid arthritis (RA) is a chronic multisystem disease with a complex immunopathology. Its inflammatory state is dominated by pro‐inflammatory cytokines…”
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Using quality indicators to compare outcomes of permanent cardiac pacemaker implantation among publicly and privately funded patients
Published in Internal medicine journal (01-08-2015)“…Background Funding source/insurance status has been associated with disparity in the management and outcomes of cardiovascular disease, with poorer outcomes…”
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Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G
Published in Glycoconjugate journal (01-02-2013)“…Human immunoglobulin G (IgG) molecules are composed of two Fab portions and one Fc portion. The glycans attached to the Fc portions of IgG are known to…”
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CYP17 gene polymorphism in relation to breast cancer risk: a case-control study
Published in Breast cancer research : BCR (01-01-2005)“…The c.1-34T>C 5' promoter region polymorphism in cytochrome P450c17 (CYP17), a key enzyme in the biosynthesis of estrogen, has been associated with breast…”
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