Search Results - "Einarsdóttir, Helga K."

The multiple facets of FcRn in immunity by Stapleton, Nigel M., Einarsdóttir, Helga K., Stemerding, Annette M., Vidarsson, Gestur

“…Summary The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in various tissues, providing newborns with humoral immunity, and for…”
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Resolution of Th/Tc17‐driven inflammation during anti‐TNFα treatment of rheumatoid arthritis reveals a unique immune biomarker profiling pattern by Bjarnadóttir, Una, Einarsdóttir, Helga K., Stefánsdóttir, Elínborg, Helgason, Einar Axel, Jónasdóttir, Dagrún, Gudmundsson, Sveinn, Gudbjornsson, Bjorn, Ludviksson, Björn R.

“…Rheumatoid arthritis (RA) is a chronic multisystem disease with a complex immunopathology. Its inflammatory state is dominated by pro‐inflammatory cytokines…”
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Familial monoclonal gammopathy: hyper-responsive B cells in unaffected family members by Steingrímsdóttir, Hlíf, Einarsdóttir, Helga K., Haraldsdóttir, Vilhelmína, Ögmundsdóttir, Helga M.

“…Background:  In Iceland, eight families have been identified with multiple cases of monoclonal gammopathies (MG) and other lymphoproliferative diseases. In one…”
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A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy by Kapur, Rick, Kustiawan, Iwan, Vestrheim, Anne, Koeleman, Carolien A.M., Visser, Remco, Einarsdottir, Helga K., Porcelijn, Leendert, Jackson, Dave, Kumpel, Belinda, Deelder, André M., Blank, Dennis, Skogen, Björn, Killie, Mette Kjaer, Michaelsen, Terje E., de Haas, Masja, Rispens, Theo, van der Schoot, C. Ellen, Wuhrer, Manfred, Vidarsson, Gestur

“…Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia…”
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Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice by Braster, Rens, Grewal, Simran, Visser, Remco, Einarsdottir, Helga K, van Egmond, Marjolein, Vidarsson, Gestur, Bögels, Marijn

“…Current anti-cancer therapeutic antibodies that are used in the clinic are predominantly humanized or fully human immunoglobulin G1 (IgG1). These antibodies…”
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Transitional B Cells and TLR9 Responses Are Defective in Selective IgA Deficiency by Lemarquis, Andri L, Einarsdottir, Helga K, Kristjansdottir, Rakel N, Jonsdottir, Ingileif, Ludviksson, Bjorn R

“…Selective IgA deficiency (IgAD) is the most common primary antibody deficiency in the western world with affected individuals suffering from an increased…”
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On the perplexingly low rate of transport of IgG2 across the human placenta by Einarsdottir, Helga K, Stapleton, Nigel M, Scherjon, Sicco, Andersen, Jan Terje, Rispens, Theo, van der Schoot, C Ellen, Vidarsson, Gestur

“…The neonatal receptor, FcRn, mediates both serum half-life extension as well as active transport of maternal IgG to the fetus during pregnancy. Therefore,…”
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Mapping of Signaling Pathways Linked to sIgAD Reveals Impaired IL-21 Driven STAT3 B-Cell Activation by Lemarquis, Andri L, Theodors, Fannar, Einarsdottir, Helga K, Ludviksson, Bjorn R

“…It has recently been shown that individuals with selective IgA deficiency (sIgAD) have defective B cell responses both to T cell dependent and independent…”
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Intranasal Administration of Antibody-Bound Respiratory Syncytial Virus Particles Efficiently Primes Virus-Specific Immune Responses in Mice by Kruijsen, Debby, Einarsdottir, Helga K, Schijf, Marcel A, Coenjaerts, Frank E, van der Schoot, Ellen C, Vidarsson, Gestur, van Bleek, Grada M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Familial Predisposition to Monoclonal Gammopathy of Unknown Significance, Waldenström's Macroglobulinemia, and Multiple Myeloma by Ögmundsdóttir, Helga M., Einarsdóttir, Helga K., Steingrímsdóttir, Hlíf, Haraldsdóttir, Vilhelmína

“…The medical literature contains reports of around 130 families with two or more cases of MM, MGUS, or WM. An Icelandic family with multiple cases of MGUS, WM,…”
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IgG-effector functions: “The Good, The Bad and The Ugly” by Kapur, Rick, Einarsdottir, Helga K, Vidarsson, Gestur

“…Highlights • FcγR polymorphisms affect binding to IgG and thereby strength of immune reactions. • Likewise, FcγR-IgG binding is affected by which IgG…”
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Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G by Einarsdottir, Helga K., Selman, Maurice H. J., Kapur, Rick, Scherjon, Sicco, Koeleman, Carolien A. M., Deelder, André M., van der Schoot, C. Ellen, Vidarsson, Gestur, Wuhrer, Manfred

“…Human immunoglobulin G (IgG) molecules are composed of two Fab portions and one Fc portion. The glycans attached to the Fc portions of IgG are known to…”
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On the Perplexingly Low Rate of Transport of IgG2 across the Human Placenta: e108319 by Einarsdottir, Helga K, Stapleton, Nigel M, Scherjon, Sicco, Andersen, Jan Terje, Rispens, Theo, Schoot, Ellen vander, Vidarsson, Gestur

“…The neonatal receptor, FcRn, mediates both serum half-life extension as well as active transport of maternal IgG to the fetus during pregnancy. Therefore,…”
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