Search Results - "Eijkemans, Marinus J."
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No rationale for 1 variable per 10 events criterion for binary logistic regression analysis
Published in BMC medical research methodology (24-11-2016)“…Ten events per variable (EPV) is a widely advocated minimal criterion for sample size considerations in logistic regression analysis. Of three previous…”
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Sample size for binary logistic prediction models: Beyond events per variable criteria
Published in Statistical methods in medical research (01-08-2019)“…Binary logistic regression is one of the most frequently applied statistical approaches for developing clinical prediction models. Developers of such models…”
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Identifying multivariate disease trajectories and potential phenotypes of early knee osteoarthritis in the CHECK cohort
Published in PloS one (14-07-2023)“…To gain better understanding of osteoarthritis (OA) heterogeneity and its predictors for distinguishing OA phenotypes. This could provide the opportunity to…”
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Predicting the Unpredictable: A New Prediction Model for Operating Room Times Using Individual Characteristics and the Surgeon's Estimate
Published in Anesthesiology (Philadelphia) (2010)“…: Routine predictions made by surgeons or historical mean durations have only limited capacity to predict operating room (OR) time. The authors aimed to devise…”
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Published in Nature medicine (01-07-2024)“…Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF trial…”
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Pre-Conception Characteristics Predict Obstetrical and Neonatal Outcomes in Women With Polycystic Ovary Syndrome
Published in The journal of clinical endocrinology and metabolism (01-03-2019)“…Women with polycystic ovary syndrome (PCOS) are at increased risk for obstetric and perinatal complications. At present, it is unknown how characteristics of…”
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Realizing a desired family size: when should couples start?
Published in Human reproduction (Oxford) (01-09-2015)“…STUDY QUESTION Until what age can couples wait to start a family without compromising their chances of realizing the desired number of children? SUMMARY ANSWER…”
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Can Menopause Prediction Be Improved With Multiple AMH Measurements? Results From the Prospective Doetinchem Cohort Study
Published in The journal of clinical endocrinology and metabolism (01-11-2019)“…Abstract Context Anti-Müllerian hormone (AMH) levels are used worldwide as a screening tool for the duration of the female reproductive lifespan. Although AMH…”
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Treatment of Vulvar Intraepithelial Neoplasia with Topical Imiquimod
Published in The New England journal of medicine (03-04-2008)“…The efficacy of local treatment of vulvar intraepithelial neoplasia with imiquimod, an immune-response modifier, was tested in a double-blind, randomized…”
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The cardiovascular risk profile of middle age women previously diagnosed with premature ovarian insufficiency: A case-control study
Published in PloS one (05-03-2020)“…Cardiovascular disease (CVD) is the leading cause of death in women worldwide. The cardiovascular risk profile deteriorates after women enter menopause. By…”
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Exacerbated innate host response to SARS-CoV in aged non-human primates
Published in PLoS pathogens (01-02-2010)“…The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and influenza A H5N1,…”
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Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial
Published in Human reproduction (Oxford) (01-04-2007)“…BACKGROUND To test whether ovarian stimulation for in-vitro fertilization (IVF) affects oocyte quality and thus chromosome segregation behaviour during meiosis…”
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Individual participant data meta‐analysis of intervention studies with time‐to‐event outcomes: A review of the methodology and an applied example
Published in Research synthesis methods (01-03-2020)“…Many randomized trials evaluate an intervention effect on time‐to‐event outcomes. Individual participant data (IPD) from such trials can be obtained and…”
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Comparison of statistical methods for the analysis of recurrent adverse events in the presence of non-proportional hazards and unobserved heterogeneity: a simulation study
Published in BMC medical research methodology (20-01-2022)“…In preventive drug trials such as intermittent preventive treatment for malaria prevention during pregnancy (IPTp), where there is repeated treatment…”
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Systematic review of statistical methods for safety data in malaria chemoprevention in pregnancy trials
Published in Malaria journal (20-03-2020)“…Drug safety assessments in clinical trials present unique analytical challenges. Some of these include adjusting for individual follow-up time, repeated…”
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Individual treatment effect estimation in the presence of unobserved confounding using proxies: a cohort study in stage III non-small cell lung cancer
Published in Scientific reports (07-04-2022)“…Randomized Controlled Trials (RCT) are the gold standard for estimating treatment effects but some important situations in cancer care require treatment effect…”
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A mild treatment strategy for in-vitro fertilisation: a randomised non-inferiority trial
Published in The Lancet (British edition) (03-03-2007)“…Summary Background Mild in-vitro fertilisation (IVF) treatment might lessen both patients' discomfort and multiple births, with their associated risks. We…”
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The Ross Procedure : A Systematic Review and Meta-Analysis
Published in Circulation (New York, N.Y.) (20-01-2009)“…Reports on outcome after the Ross procedure are limited by small study size and show variable durability results. A systematic review of evidence on outcome…”
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Factors affecting the accuracy of a class prediction model in gene expression data
Published in BMC bioinformatics (21-06-2015)“…Class prediction models have been shown to have varying performances in clinical gene expression datasets. Previous evaluation studies, mostly done in the…”
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Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women
Published in Human reproduction (Oxford) (01-02-2008)“…BACKGROUND Obesity is increasing rapidly among women all over the world. Obesity is a known risk factor for subfertility due to anovulation, but it is unknown…”
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