Search Results - "Eidhoff, Ulf"

Structural basis for the regulatory interactions of proapoptotic Par-4 by Tiruttani Subhramanyam, Udaya K, Kubicek, Jan, Eidhoff, Ulf B, Labahn, Joerg

“…Par-4 is a unique proapoptotic protein with the ability to induce apoptosis selectively in cancer cells. The X-ray crystal structure of the C-terminal domain…”
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Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2 by Renatus, Martin, Parrado, Shirley Gil, D'Arcy, Allan, Eidhoff, Ulf, Gerhartz, Bernd, Hassiepen, Ulrich, Pierrat, Benoit, Riedl, Ralph, Vinzenz, Daniela, Worpenberg, Susanne, Kroemer, Markus

“…Deubiquitinating proteases reverse protein ubiquitination and rescue their target proteins from destruction by the proteasome. USP2, a cysteine protease and a…”
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Cloning, expression, purification, crystallization and preliminary crystallographic analysis of the C-terminal domain of Par-4 (PAWR) by Tiruttani Subhramanyam, Udaya Kumar, Kubicek, Jan, Eidhoff, Ulf B., Labahn, Joerg

“…Prostate apoptosis response‐4 protein is an intrinsically disordered pro‐apoptotic protein with tumour suppressor function. Par‐4 is known for its selective…”
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A sensitive fluorescence intensity assay for deubiquitinating proteases using ubiquitin-rhodamine110-glycine as substrate by Hassiepen, Ulrich, Eidhoff, Ulf, Meder, Gabriele, Bulber, Jean-Francois, Hein, Andreas, Bodendorf, Ursula, Lorthiois, Edwige, Martoglio, Bruno

“…The dynamic modification of proteins with ubiquitin is a key regulation paradigm in eukaryotic cells that controls stability, localization, and function of the…”
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Crystal Structure of Human BACE2 in Complex with a Hydroxyethylamine Transition-state Inhibitor by Ostermann, Nils, Eder, Jörg, Eidhoff, Ulf, Zink, Florence, Hassiepen, Ulrich, Worpenberg, Susanne, Maibaum, Jürgen, Simic, Oliver, Hommel, Ulrich, Gerhartz, Bernd

“…BACE2 is a membrane-bound aspartic protease of the A1 family with a high level of sequence homology to BACE1. While BACE1 is involved in the generation of…”
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Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2 by Tirat, Aline, Schilb, Alain, Riou, Virginie, Leder, Lukas, Gerhartz, Bernd, Zimmermann, Johann, Worpenberg, Susanne, Eidhoff, Ulf, Freuler, Felix, Stettler, Thomas, Mayr, Lorenz, Ottl, Johannes, Leuenberger, Beate, Filipuzzi, Ireos

“…Deubiquitinating enzymes (DUBs) catalyze the removal of attached ubiquitin molecules from amino groups of target proteins. The large family of DUBs plays an…”
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Backbone 1H, 13C, and 15N resonance assignments for the 26-kD human de-ubiquitinating enzyme UCH-L3 by Harris, Richard, Eidhoff, Ulf, Vinzenz, Daniela, Renatus, Martin, Gerhartz, Bernd, Hommel, Ulrich, Driscoll, Paul C

“…To facilitate NMR spectroscopy studies of interactions with various ligands and potential inhibitors, we report the NMR backbone resonance assignments for the…”
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Increased oncogenicity of subclones of SV40 large T-induced neuroectodermal tumor cell lines after loss of large T expression and concomitant mutation in p53 by SALEWSKI, H, BAYER, T. A, EIDHOFF, U, PREUSS, U, WEGGEN, S, SCHEIDTMANN, K. H

“…A model for medulloblastoma-like primitive neuroectodermal tumors was established in rat using retrovirally transduced SV40 large T antigen (LT) as an inducing…”
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