Search Results - "Eidem, Tess M."
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Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders
Published in Journal of neurochemistry (01-03-2009)“…Brain inflammation is a complex cellular and molecular response to stress, injury or infection of the CNS in attempt to defend against insults, clear dead and…”
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LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens
Published in mBio (30-09-2014)“…The problem of multidrug resistance in serious Gram-negative bacterial pathogens has escalated so severely that new cellular targets and pathways need to be…”
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Noncoding RNAs: Regulators of the Mammalian Transcription Machinery
Published in Journal of molecular biology (19-06-2016)“…Transcription by RNA polymerase II (Pol II) is required to produce mRNAs and some noncoding RNAs (ncRNAs) within mammalian cells. This coordinated process is…”
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Infection by Herpes Simplex Virus 1 Causes Near-Complete Loss of RNA Polymerase II Occupancy on the Host Cell Genome
Published in Journal of virology (01-03-2016)“…Lytic infection by herpes simplex virus 1 (HSV-1) triggers a change in many host cell programs as the virus strives to express its own genes and replicate…”
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Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus
Published in Bioorganic & medicinal chemistry (23-07-2018)“…[Display omitted] Antibiotic resistance is a serious threat to global public health, and methicillin-resistant Staphylococcus aureus (MRSA) is a poignant…”
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Small-molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing
Published in Antimicrobial agents and chemotherapy (01-04-2015)“…New agents are urgently needed for the therapeutic treatment of Staphylococcus aureus infections. In that regard, S. aureus RNase RnpA may represent a…”
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RNA decay: a novel therapeutic target in bacteria
Published in Wiley interdisciplinary reviews. RNA (01-05-2012)“…The need for novel antibiotics is greater now than perhaps any time since the pre‐antibiotic era. Indeed, the recent collapse of most pharmaceutical…”
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Drug-eluting cements for hard tissue repair: A comparative study using vancomycin and RNPA1000 to inhibit growth of Staphylococcus aureus
Published in Journal of biomaterials applications (01-04-2014)“…Bone cement used in orthopaedic applications can become colonized with bacterial biofilms, resulting in severe medical complications. Consequently, bone…”
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Cadmium exposures in fathead minnows : Are there sex-specific differences in mortality, reproductive success, and Cd accumulation?
Published in Archives of environmental contamination and toxicology (01-05-2007)“…The primary goal of this experiment was to determine whether cadmium (Cd) exposure has sex-specific effects on the reproductive success of fathead minnows as…”
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