Search Results - "Eidem, Tess"

Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders by Whitney, Nicholas P, Eidem, Tess M, Peng, Hui, Huang, Yunlong, Zheng, Jialin C

“…Brain inflammation is a complex cellular and molecular response to stress, injury or infection of the CNS in attempt to defend against insults, clear dead and…”
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Noncoding RNAs: Regulators of the Mammalian Transcription Machinery by Eidem, Tess M., Kugel, Jennifer F., Goodrich, James A.

“…Transcription by RNA polymerase II (Pol II) is required to produce mRNAs and some noncoding RNAs (ncRNAs) within mammalian cells. This coordinated process is…”
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Infection by Herpes Simplex Virus 1 Causes Near-Complete Loss of RNA Polymerase II Occupancy on the Host Cell Genome by Abrisch, Robert G, Eidem, Tess M, Yakovchuk, Petro, Kugel, Jennifer F, Goodrich, James A

“…Lytic infection by herpes simplex virus 1 (HSV-1) triggers a change in many host cell programs as the virus strives to express its own genes and replicate…”
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LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens by Tomaras, Andrew P, McPherson, Craig J, Kuhn, Michael, Carifa, Arlene, Mullins, Lisa, George, David, Desbonnet, Charlene, Eidem, Tess M, Montgomery, Justin I, Brown, Matthew F, Reilly, Usa, Miller, Alita A, O'Donnell, John P

“…The problem of multidrug resistance in serious Gram-negative bacterial pathogens has escalated so severely that new cellular targets and pathways need to be…”
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Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells by Ramirez, Servio H, Potula, Raghava, Fan, Shongshan, Eidem, Tess, Papugani, Anil, Reichenbach, Nancy, Dykstra, Holly, Weksler, Babette B, Romero, Ignacio A, Couraud, Pierre O, Persidsky, Yuri

“…Methamphetamine (METH), a potent stimulant with strong euphoric properties, has a high abuse liability and long-lasting neurotoxic effects. Recent studies in…”
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Transcriptional profiling of Staphylococcus aureus during growth in 2 M NaCl leads to clarification of physiological roles for Kdp and Ktr K+ uptake systems by Price-Whelan, Alexa, Poon, Chun Kit, Benson, Meredith A, Eidem, Tess T, Roux, Christelle M, Boyd, Jeffrey M, Dunman, Paul M, Torres, Victor J, Krulwich, Terry A

“…Staphylococcus aureus exhibits an unusually high level of osmotolerance and Na(+) tolerance, properties that support survival in various host niches and in…”
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Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus by Liang, Hai, Zhou, Guangfeng, Ge, Yunhui, D'Ambrosio, Elizabeth A., Eidem, Tess M., Blanchard, Catlyn, Shehatou, Cindy, Chatare, Vijay K., Dunman, Paul M., Valentine, Ann M., Voelz, Vincent A., Grimes, Catherine L., Andrade, Rodrigo B.

“…[Display omitted] Antibiotic resistance is a serious threat to global public health, and methicillin-resistant Staphylococcus aureus (MRSA) is a poignant…”
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Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA by Annadurai, Sivakumar, Martinez, Rogelio, Canney, Daniel J., Eidem, Tess, Dunman, Paul M., Abou-Gharbia, Magid

“…Privileged structure-based libraries have been shown to provide high affinity lead compounds for a variety of important biological targets. The present study…”
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Correction for Abrisch et al., Infection by Herpes Simplex Virus 1 Causes Near-Complete Loss of RNA Polymerase II Occupancy on the Host Cell Genome by Abrisch, Robert G, Eidem, Tess M, Yakovchuk, Petro, Kugel, Jennifer F, Goodrich, James A

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Small-molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing by Eidem, Tess M, Lounsbury, Nicole, Emery, John F, Bulger, Jeffrey, Smith, Andrew, Abou-Gharbia, Magid, Childers, Wayne, Dunman, Paul M

“…New agents are urgently needed for the therapeutic treatment of Staphylococcus aureus infections. In that regard, S. aureus RNase RnpA may represent a…”
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RNA decay: a novel therapeutic target in bacteria by Eidem, Tess M., Roux, Christelle M., Dunman, Paul M.

“…The need for novel antibiotics is greater now than perhaps any time since the pre‐antibiotic era. Indeed, the recent collapse of most pharmaceutical…”
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Drug-eluting cements for hard tissue repair: A comparative study using vancomycin and RNPA1000 to inhibit growth of Staphylococcus aureus by Eidem, Tess M, Coughlan, Aisling, Towler, Mark R, Dunman, Paul M, Wren, Anthony William

“…Bone cement used in orthopaedic applications can become colonized with bacterial biofilms, resulting in severe medical complications. Consequently, bone…”
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Cadmium exposures in fathead minnows : Are there sex-specific differences in mortality, reproductive success, and Cd accumulation? by SELLIN, Marlo K, EIDEM, Tess M, KOLOK, Alan S

“…The primary goal of this experiment was to determine whether cadmium (Cd) exposure has sex-specific effects on the reproductive success of fathead minnows as…”
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Bioaerosol Exposures and Respiratory Diseases in Cannabis Workers by Eidem, Tess, Nordgren, Tara, Hernandez, Mark

“…Purpose of Review This review investigates occupational inhalation hazards associated with biologically derived airborne particles (bioaerosols) generated in…”
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Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin by Lounsbury, Nicole, Eidem, Tess, Colquhoun, Jennifer, Mateo, George, Abou-Gharbia, Magid, Dunman, Paul M., Childers, Wayne E.

“…We recently discovered RnpA as a promising new drug discovery target for methicillin-resistant S. aureus (MRSA). RnpA is an essential protein that is thought…”
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Isolation of Staphylococcus sp. RNA by Eidem, Tess

“…Isolation of RNA (ribonucleic acid) is a valuable technique to study gene regulation and functional RNAs. It is important to obtain pure samples of RNA for…”
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The Ribonuclease RnpA is a Novel Target for Antimicrobial Development by Eidem, Tess Marie

“…As antibiotic-resistant bacterial pathogens increasingly evade current antimicrobial treatments, the need for new antibiotics has never been greater. We…”
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