Search Results - "Eidem, Haley R"

Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth by Huusko, Johanna M, Karjalainen, Minna K, Graham, Britney E, Zhang, Ge, Farrow, Emily G, Miller, Neil A, Jacobsson, Bo, Eidem, Haley R, Murray, Jeffrey C, Bedell, Bruce, Breheny, Patrick, Brown, Noah W, Bødker, Frans L, Litterman, Nadia K, Jiang, Pan-Pan, Russell, Laura, Hinds, David A, Hu, Youna, Rokas, Antonis, Teramo, Kari, Christensen, Kaare, Williams, Scott M, Rämet, Mika, Kingsmore, Stephen F, Ryckman, Kelli K, Hallman, Mikko, Muglia, Louis J

“…Preterm birth is a leading cause of morbidity and mortality in infants. Genetic and environmental factors play a role in the susceptibility to preterm birth,…”
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integRATE: a desirability-based data integration framework for the prioritization of candidate genes across heterogeneous omics and its application to preterm birth by Eidem, Haley R, Steenwyk, Jacob L, Wisecaver, Jennifer H, Capra, John A, Abbot, Patrick, Rokas, Antonis

“…The integration of high-quality, genome-wide analyses offers a robust approach to elucidating genetic factors involved in complex human diseases. Even though…”
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Correction: Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth by Huusko, Johanna M, Karjalainen, Minna K, Graham, Britney E, Zhang, Ge, Farrow, Emily G, Miller, Neil A, Jacobsson, Bo, Eidem, Haley R, Murray, Jeffrey C, Bedell, Bruce, Breheny, Patrick, Brown, Noah W, Bødker, Frans L, Litterman, Nadia K, Jiang, Pan-Pan, Russell, Laura, Hinds, David A, Hu, Youna, Rokas, Antonis, Teramo, Kari, Christensen, Kaare, Williams, Scott M, Rämet, Mika, Kingsmore, Stephen F, Ryckman, Kelli K, Hallman, Mikko, Muglia, Louis J

“…[This corrects the article DOI: 10.1371/journal.pgen.1007394.]…”
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Gestational tissue transcriptomics in term and preterm human pregnancies: a systematic review and meta-analysis by Eidem, Haley R, Ackerman, 4th, William E, McGary, Kriston L, Abbot, Patrick, Rokas, Antonis

“…Preterm birth (PTB), or birth before 37 weeks of gestation, is the leading cause of newborn death worldwide. PTB is a critical area of scientific study not…”
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Shared Selective Pressures on Fungal and Human Metabolic Pathways Lead to Divergent yet Analogous Genetic Responses by Eidem, Haley R, McGary, Kriston L, Rokas, Antonis

“…Reduced metabolic efficiency, toxic intermediate accumulation, and deficits of molecular building blocks, which all stem from disruptions of flux through…”
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The transformative potential of an integrative approach to pregnancy by Eidem, Haley R., McGary, Kriston L., Capra, John A., Abbot, Patrick, Rokas, Antonis

“…Complex traits typically involve diverse biological pathways and are shaped by numerous genetic and environmental factors. Pregnancy-associated traits and…”
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Comprehensive RNA profiling of villous trophoblast and decidua basalis in pregnancies complicated by preterm birth following intra-amniotic infection by Ackerman, William E, Buhimschi, Irina A, Eidem, Haley R, Rinker, David C, Rokas, Antonis, Rood, Kara, Zhao, Guomao, Summerfield, Taryn L, Landon, Mark B, Buhimschi, Catalin S

“…Abstract Introduction We performed RNA sequencing with the primary goal of discovering key placental villous trophoblast (VT) and decidua basalis (DB)…”
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Comparing human and macaque placental transcriptomes to disentangle preterm birth pathology from gestational age effects by Eidem, Haley R, Rinker, David C, Ackerman, William E, Buhimschi, Irina A, Buhimschi, Catalin S, Dunn-Fletcher, Caitlin, Kallapur, Suhas G, Pavličev, Mihaela, Muglia, Louis J, Abbot, Patrick, Rokas, Antonis

“…Abstract Introduction A major issue in the transcriptomic study of spontaneous preterm birth (sPTB) in humans is the inability to collect healthy control…”
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GEneSTATION 1.0: a synthetic resource of diverse evolutionary and functional genomic data for studying the evolution of pregnancy-associated tissues and phenotypes by Kim, Mara, Cooper, Brian A, Venkat, Rohit, Phillips, Julie B, Eidem, Haley R, Hirbo, Jibril, Nutakki, Sashank, Williams, Scott M, Muglia, Louis J, Capra, J Anthony, Petren, Kenneth, Abbot, Patrick, Rokas, Antonis, McGary, Kriston L

“…Mammalian gestation and pregnancy are fast evolving processes that involve the interaction of the fetal, maternal and paternal genomes. Version 1.0 of the…”
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