Search Results - "Eid, Samer R"

The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept by Szallasi, Arpad, Cortright, Daniel N, Blum, Charles A, Eid, Samer R

“…The clinical use of TRPV1 (transient receptor potential vanilloid subfamily, member 1; also known as VR1) antagonists is based on the concept that endogenous…”
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Therapeutic targeting of TRP channels--the TR(i)P to pain relief by Eid, Samer R

“…Following the cloning and characterization of the transient receptor potential vanilloid 1 (TRPV1), a growing body of research has identified the important…”
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HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity by Eid, Samer R, Crown, Eric D, Moore, Eric L, Liang, Hongyu A, Choong, Kar-Chan, Dima, Shelley, Henze, Darrell A, Kane, Stefanie A, Urban, Mark O

“…Background: Safe and effective treatment for chronic inflammatory and neuropathic pain remains a key unmet medical need for many patients. The recent discovery…”
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The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin by Macpherson, Lindsey J., Geierstanger, Bernhard H., Viswanath, Veena, Bandell, Michael, Eid, Samer R., Hwang, SunWook, Patapoutian, Ardem

“…Garlic’s pungent flavor has made it a popular ingredient in cuisines around the world and throughout history. Garlic’s health benefits have been elevated from…”
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Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin by Bandell, Michael, Story, Gina M, Hwang, Sun Wook, Viswanath, Veena, Eid, Samer R, Petrus, Matt J, Earley, Taryn J, Patapoutian, Ardem

“…Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The natural compounds capsaicin and…”
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ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures by Story, Gina M., Peier, Andrea M., Reeve, Alison J., Eid, Samer R., Mosbacher, Johannes, Hricik, Todd R., Earley, Taryn J., Hergarden, Anne C., Andersson, David A., Hwang, Sun Wook, McIntyre, Peter, Jegla, Tim, Bevan, Stuart, Patapoutian, Ardem

“…Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been implicated in sensing heat, and one…”
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The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept by Szallasi, Arpad, Cortright, Daniel N, Blum, Charles A, Eid, Samer R

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Xenopus Na,K-ATPase: primary sequence of the β2 subunit and in situ localization of α1, β1, and γ expression during pronephric kidney development by Eid, Samer R., Brändli, André W.

“…The osmoregulatory function of the pronephric kidney, the first excretory organ of the vertebrate embryo, is essential for embryonic survival. The transport…”
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Embryonic expression of Xenopus SGLT-1L, a novel member of the solute carrier family 5 (SLC5), is confined to tubules of the pronephric kidney by Eid, Samer R, Terrettaz, Anne, Nagata, Katsumi, Brändli, André W

“…Plasma membrane proteins of the solute carrier family 5 (SLC5) are responsible for sodium-coupled uptake of ions, sugars and nutrients in the vertebrate body…”
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Erratum: The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept by Szallasi, Arpad, Cortright, Daniel N., Blum, Charles A., Eid, Samer R.

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