Search Results - "Eid, Saada"

Assessment of the therapeutic role of mesenchymal stromal cells in a mouse model of graft-versus-host disease using cryo-imaging by Wuttisarnwattana, Patiwet, Eid, Saada, Wilson, David L., Cooke, Kenneth R.

“…Insights regarding the biodistribution and homing of mesenchymal stromal cells (MSCs), as well as their interaction with alloreactive T-cells are critical for…”
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Author Correction: Assessment of the therapeutic role of mesenchymal stromal cells in a mouse model of graft-versus-host disease using cryo-imaging by Wuttisarnwattana, Patiwet, Eid, Saada, Wilson, David L., Cooke, Kenneth R.

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Cryo-imaging of Stem Cell Biodistribution in Mouse Model of Graft-Versus-Host-Disease by Wuttisarnwattana, Patiwet, Eid, Saada, Gargesha, Madhusudhana, Cooke, Kenneth R., Wilson, David L.

“…We demonstrated the use of multispectral cryo-imaging and software to analyze human mesenchymal stromal cells (hMSCs) biodistribution in mouse models of…”
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Human Mesenchymal Stromal Cells Attenuate Graft‐Versus‐Host Disease and Maintain Graft‐Versus‐Leukemia Activity Following Experimental Allogeneic Bone Marrow Transplantation by Auletta, Jeffery J., Eid, Saada K., Wuttisarnwattana, Patiwet, Silva, Ines, Metheny, Leland, Keller, Matthew D., Guardia‐Wolff, Rocio, Liu, Chen, Wang, Fangjing, Bowen, Theodore, Lee, Zhenghong, Solchaga, Luis A., Ganguly, Sudipto, Tyler, Megan, Wilson, David L., Cooke, Kenneth R.

“…We sought to define the effects and underlying mechanisms of human, marrow‐derived mesenchymal stromal cells (hMSCs) on graft‐versus‐host disease (GvHD) and…”
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Human multipotent adult progenitor cells effectively reduce graft‐vs‐host disease while preserving graft‐vs‐leukemia activity by Metheny, Leland, Eid, Saada, Wuttisarnwattana, Patiwet, Auletta, Jeffery J., Liu, Chen, Van Dervort, Alana, Paez, Conner, Lee, ZhengHong, Wilson, David, Lazarus, Hillard M., Deans, Robert, Vant Hof, Wouter, Ktena, Yiouli, Cooke, Kenneth R.

“…Graft‐vs‐host disease (GvHD) limits successful outcomes following allogeneic blood and marrow transplantation (allo‐BMT). We examined whether the…”
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CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNγ with Dependency on Natural Killer Cells by Allen, Frederick, Rauhe, Peter, Askew, David, Tong, Alexander A, Nthale, Joseph, Eid, Saada, Myers, Jay T, Tong, Caryn, Huang, Alex Y

“…Lymph node (LN) plays a critical role in tumor cell survival outside of the primary tumor sites and dictates overall clinical response in many tumor types (1,…”
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Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation by Alshebremi, Mohammad, Tomchuck, Suzanne L, Myers, Jay T, Kingsley, Daniel T, Eid, Saada, Abiff, Muta, Bonner, Melissa, Saab, Shahrazad T, Choi, Sung Hee, Huang, Alex Yee-Chen

“…Despite its potential utility in delivering direct tumor killing and in situ whole-cell tumor vaccination, tumor cryoablation produces highly variable and…”
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Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity by Choi, Sung Hee, Myers, Jay Thomas, Tomchuck, Suzanne Louise, Bonner, Melissa, Eid, Saada, Kingsley, Daniel Tyler, VanHeyst, Kristen Ashley, Kim, Seong‐Jin, Kim, Byung‐Gyu, Huang, Alex Yee‐Chen

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Adoptive natural killer cell therapy is effective in reducing pulmonary metastasis of Ewing sarcoma by Tong, Alexander A., Hashem, Hasan, Eid, Saada, Allen, Frederick, Kingsley, Daniel, Huang, Alex Y.

“…The survival of patients with metastatic or relapsed Ewing sarcoma (ES) remains dismal despite intensification of combination chemotherapy and radiotherapy,…”
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Posttransplant Intramuscular Injection of PLX-R18 Mesenchymal-Like Adherent Stromal Cells Improves Human Hematopoietic Engraftment in A Murine Transplant Model by Metheny, Leland, Eid, Saada, Lingas, Karen, Ofir, Racheli, Pinzur, Lena, Meyerson, Howard, Lazarus, Hillard M, Huang, Alex Y

“…Late-term complications of hematopoietic cell transplantation (HCT) are numerous and include incomplete engraftment. One possible mechanism of incomplete…”
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Etanercept clearance during an in vitro model of continuous venovenous hemofiltration by Fleming, Geoffrey M, Salama, Noha N, Eid, Saada K, Cooke, Kenneth R, Mueller, Bruce A

“…Etanercept is a tumor necrosis factor-alpha antagonist used in inflammation-mediated conditions. Continuous venovenous hemofiltration (CVVH) has also been used…”
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Assessment of therapeutic role of mesenchymal stromal cells in mouse models of graft-versus-host disease using cryo-imaging by Wuttisarnwattana, Patiwet, Eid, Saada, Wilson, David L, Cooke, Kenneth R

“…Insights regarding the biodistribution and homing of mesenchymal stromal cells (MSCs), as well as their interaction with alloreactive T-cells are critical for…”
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Mechanosensory channel Piezo1 is essential in pathogenic T cell-mediated intestinal inflammation by Choi, Sung Hee, Aguilar, Alicia, Myers, Jay, Kim, Byung-Gyu, Eid, Saada, Tomchuck, Suzanne, Kingsley, Daniel, Huang, Alex

“…Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the gastrointestinal tract. CD4+ T cells are especially known to be the main drivers of…”
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Piezo1 restrains proinflammatory response but is essential in T cell-mediated immunopathology by Choi, Sung Hee, Santin, Alicia, Myers, Jay T, Kim, Byung-Gyu, Eid, Saada, Tomchuck, Suzanne L, Kingsley, Daniel T, Huang, Alex Y

“…Piezo1 is a mechanosensitive, nonselective Ca2+ channel which is broadly expressed in CD4+ T cells. Using lineage-specific Piezo1 knockout mice (Piezo1cKO), we…”
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CCL3 augment antitumor immune priming in the tumor draining lymph node by Allen, Frederick, Rauhe, Peter, Askew, David, Eid, Saada, Nthale, Joseph, Myers, Jay, Tong, Alexander, Huang, Alex Yee-Chen

“…Lymph nodes (LNs) represent an area of interest for targeting metastatic tumors because they play an essential role in tumor survival in non-native tissues…”
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Abstract 728: Oral TGF-beta receptor1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity by Choi, Sung Hee, Myers, Jay, Tomchuck, Suzanne, Bonner, Melissa, Eid, Saada, Kingsley, Daniel, VanHeyst, Kristen, Kim, Seong-Jin, Kim, Byung-Gyu, Huang, Alex Y.

“…Osteosarcoma (OS) is an aggressive malignant bone cancer, with the lung as the most frequent site of metastasis. Unresectable pulmonary metastasis remains a…”
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Cyclin-dependent kinase 5 activity is required for allogeneic T-cell responses after hematopoietic cell transplantation in mice by Askew, David, Pareek, Tej K., Eid, Saada, Ganguly, Sudipto, Tyler, Megan, Huang, Alex Y., Letterio, John J., Cooke, Kenneth R.

“…Molecular intermediates in T-cell activation pathways are crucial targets for the therapy and prevention of graft-versus-host disease (GVHD) following…”
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Intra-Osseous Co-Transplantation of CD34-Selected Umbilical Cord Blood and Mesenchymal Stromal Cells by Metheny, Leland, de Lima, Marcos, Gerson, Stanton, Eid, Saada, Huang, Alex Yee-Chen

“…Introduction. Intra-Osseous (IO) transplantation has been proposed as a strategy to enhance human UCB (umbilical cord blood; hUCB) engraftment in NOD…”
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VCAM-1 enhances immune evasion in a murine model of metastatic cervical cancer (TUM7P.938) by Huang, Alex, Scrimieri, Francesca, Tong, Alexander, Askew, David, Eid, Saada, Bobanga, Iuliana, Corn, David

“…Surface over-expression of Vascular Cell Adhesion Molecule-1 (VCAM-1) was shown to provide a pro-survival advantage in metastatic breast cancer. Similarly, the…”
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Abstract 1174: VCAM-1 enhances immune evasion in a murine model of metastatic cervical cancer by Scrimieri, Francesca, Bobanga, Iuliana Dit, Eid, Saada, Corn, David J., Barkauskas, Deborah, Myers, Jay Jay, Huang, Alex Y.

“…Surface over-expression of Vascular Cell Adhesion Molecule-1 (VCAM-1) has recently been identified as a mechanism used by metastatic breast cancer cells to…”
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