Search Results - "Eid, Eltayeb E M"
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Characterization of Thymoquinone-Sulfobutylether-β-Cyclodextrin Inclusion Complex for Anticancer Applications
Published in Molecules (Basel, Switzerland) (15-05-2023)“…Thymoquinone (TQ) is a quinone derived from the black seed and has been extensively studied in pharmaceutical and nutraceutical research due to its therapeutic…”
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2
Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide
Published in Molecules (Basel, Switzerland) (13-07-2019)“…Cell-penetrating peptides (CPPs) are highly promising tools to deliver therapeutic molecules into tumours. αVβ3 integrins are cell-matrix adhesion receptors,…”
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3
Enhancing the Anti-Leukemic Potential of Thymoquinone/Sulfobutylether-β-cyclodextrin (SBE-β-CD) Inclusion Complexes
Published in Biomedicines (04-07-2023)“…Leukemia, a condition characterized by the abnormal proliferation of blood cells, poses significant challenges in cancer treatment. Thymoquinone (TQ), a…”
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4
Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration
Published in International journal of nanomedicine (01-01-2013)“…Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and surfactants are potentially good colloidal drug carriers. Thymoquinone is the…”
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5
Cytotoxicity of nickel zinc ferrite nanoparticles on cancer cells of epithelial origin
Published in International journal of nanomedicine (01-01-2013)“…In this study, in vitro cytotoxicity of nickel zinc (NiZn) ferrite nanoparticles against human colon cancer HT29, breast cancer MCF7, and liver cancer HepG2…”
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Cardamonin Exerts Antitumor Effect on Human Hepatocellular Carcinoma Xenografts in Athymic Nude Mice through Inhibiting NF-κβ Pathway
Published in Biomedicines (09-12-2020)“…Cardamonin (CADMN) exerts an in vitro antiproliferative and apoptotic actions against human hepatocellular carcinoma cells (HepG2). This study aimed to…”
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7
Targeting SARS-CoV-2 main protease by teicoplanin: A mechanistic insight by docking, MM/GBSA and molecular dynamics simulation
Published in Journal of molecular structure (15-12-2021)“…•Molecular interaction of teicoplanin was studied with SARS-Cov-2 main protease.•Both monomeric and dimeric forms of MPro were used.•Teicoplanin was optimized…”
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8
Probiotics supplementation in patients with colorectal cancer: a systematic review of randomized controlled trials
Published in Nutrition reviews (08-12-2021)“…Abstract Context Colorectal cancer (CRC) is a leading cause of cancer deaths. Recently, much attention has been given to the microbiome and probiotics as…”
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9
Induction of apoptosis in cancer cells by NiZn ferrite nanoparticles through mitochondrial cytochrome C release
Published in International journal of nanomedicine (01-01-2013)“…The long-term objective of the present study was to determine the ability of NiZn ferrite nanoparticles to kill cancer cells. NiZn ferrite nanoparticle…”
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10
Liquid chromatography-tandem mass spectroscopic method for the determination of zerumbone in human plasma and its application to pharmacokinetics
Published in Journal of mass spectrometry. (01-08-2011)“…A rapid, sensitive, specific and selective LC–MS/MS method for the determination of zerumbone (ZER) in human plasma using…”
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11
An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α
Published in Journal of biomolecular structure & dynamics (13-04-2022)“…Ivermectin (IVM) is a broad-spectrum antiparasitic agent, having inhibitory potential against wide range of viral infections. It has also been found to hamper…”
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12
Characterization of thymoquinone/hydroxypropyl-β-cyclodextrin inclusion complex: Application to anti-allergy properties
Published in European journal of pharmaceutical sciences (15-05-2019)“…Thymoquinone is an effective phytochemical compound in the treatment of various diseases. However, its practical administration has been limited due to poor…”
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13
Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin
Published in Carbohydrate polymers (01-02-2011)“…In this paper we investigated the inclusion complexation between zerumbone (ZER) and hydroxylpropyl-β-cyclodextrin (HPβCD) at four different temperatures:…”
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14
Dispersive solid-phase extraction for simultaneous determination of four amphetamines drugs in urine using gas chromatography–mass spectrometry
Published in Journal of the Iranian Chemical Society (01-03-2022)“…A sample preparation method based on modified Quick, Easy, Cheap Effective, Rugged, and Safe (QuEChERS) and GC–MS method was developed and validated for…”
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15
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published in Biomedicine & pharmacotherapy (01-06-2021)“…The aim of this study was to prepare, characterize, and determine the in vitro anticancer effects of platinum-doped magnesia (Pt/MgO) nanoparticles. The…”
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Zerumbone binding to estrogen receptors: an in-silico investigation
Published in Journal of receptors and signal transduction (01-08-2018)“…Breast cancer is the most frequent malignancy among females worldwide. Estrogen receptor (ER) mediate important pathophysiological signaling pathways induced…”
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Preparation, characterization, in vitro drug release and anti-inflammatory of thymoquinone-loaded chitosan nanocomposite
Published in Saudi pharmaceutical journal (01-04-2022)“…In this study, we formulated Thymoquinone-loaded nanocomposites (TQ-NCs) using high-pressure homogenizer without sodium tripolyphosphate. The TQ-NCs were…”
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18
The impact of single and double hydrogen bonds on crystallization and melting regimes of Ajwa and Barni lipids
Published in Food research international (01-10-2012)“…The present study was conducted to assess the impact of single and double hydrogen (H2) bonds of the prominent long chain triacylglycerols (TAGs) of Ajwa and…”
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Characterization, drug release profile and cytotoxicity of Dentatin-Hydroxypropyl-β-Cyclodextrin complex
Published in Journal of inclusion phenomena and macrocyclic chemistry (01-02-2017)“…This current work has been conducted mainly to increase solubility and drug release properties for high hydrophobic Dentatin (DEN) by incorporation it into…”
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Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…Zerumbone (ZER) isolated from Zingiber zerumbet was previously encapsulated with hydroxypropyl-β-cyclodextrin (HPβCD) to enhance ZER’s solubility in water,…”
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