Search Results - "Eid, Assaad A"

Gut microbiota and mTOR signaling: Insight on a new pathophysiological interaction by Noureldein, Mohamed H., Eid, Assaad A.

“…The gut microbiota plays a substantial role in regulating the host metabolic and immune functions. Dysbiosis, resulting from disruption of gut microbiota,…”
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Butyrate modulates diabetes-linked gut dysbiosis: epigenetic and mechanistic modifications by Noureldein, Mohamed H, Bitar, Sara, Youssef, Natalie, Azar, Sami, Eid, Assaad A

“…Diabetic dysbiosis has been described as a novel key player in diabetes and diabetic complications. However, the cellular/molecular alterations associated with…”
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Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases by Gorin, Yves, Eid, Assaad, Eid, Ali H., Pasha, Mazhar, Munusamy, Shankar

“…Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against…”
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Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression by Eid, Assaad A., Lee, Doug-Yoon, Roman, Linda J., Khazim, Khaled, Gorin, Yves

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes by Eid, Assaad A., Ford, Bridget M., Block, Karen, Kasinath, Balakuntalam S., Gorin, Yves, Ghosh-Choudhury, Goutam, Barnes, Jeffrey L., Abboud, Hanna E.

“…Diabetes and high glucose (HG) increase the generation of NADPH oxidase-derived reactive oxygen species and induce apoptosis of glomerular epithelial cells…”
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Wearable flexible body matched electromagnetic sensors for personalized non-invasive glucose monitoring by Hanna, Jessica, Tawk, Youssef, Azar, Sami, Ramadan, Ali H., Dia, Batoul, Shamieh, Elias, Zoghbi, Sumaya, Kanj, Rouwaida, Costantine, Joseph, Eid, Assaad A.

“…This work introduces novel body-matched, vasculature-inspired, quasi-antenna-arrays that act as electromagnetic sensors to instantaneously, continuously, and…”
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Immune Checkpoint Inhibitor-Induced Diabetes Mellitus: Potential Role of T Cells in the Underlying Mechanism by Mourad, Diane, Azar, Nadim S, Eid, Assaad A, Azar, Sami T

“…Immunotherapy is now a recognized treatment option for several types of cancer. However, some cancer patients treated with immune checkpoint inhibitors (ICIs)…”
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Noninvasive, wearable, and tunable electromagnetic multisensing system for continuous glucose monitoring, mimicking vasculature anatomy by Hanna, Jessica, Bteich, Moussa, Tawk, Youssef, Ramadan, Ali H, Dia, Batoul, Asadallah, Fatima A, Eid, Aline, Kanj, Rouwaida, Costantine, Joseph, Eid, Assaad A

“…Painless, needle-free, and continuous glucose monitoring sensors are needed to enhance the life quality of diabetic patients. To that extent, we propose a…”
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Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury by EID, Assaad A, FORD, Bridget M, BHANDARY, Basant, DE CASSIA CAVAGLIERI, Rita, BLOCK, Karen, BARNES, Jeffrey L, GORIN, Yves, GOUTAM GHOSH CHOUDHURY, ABBOUD, Hanna E

“…Podocyte apoptosis is a critical mechanism for excessive loss of urinary albumin that eventuates in kidney fibrosis. Pharmacological doses of the mammalian…”
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The Mitochondria: A Target of Polyphenols in the Treatment of Diabetic Cardiomyopathy by Bhagani, Humna, Nasser, Suzanne A, Dakroub, Ali, El-Yazbi, Ahmed F, Eid, Assaad A, Kobeissy, Firas, Pintus, Gianfranco, Eid, Ali H

“…Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The…”
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Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders by Dakroub, Ali, A Nasser, Suzanne, Younis, Nour, Bhagani, Humna, Al-Dhaheri, Yusra, Pintus, Gianfranco, Eid, Assaad A, El-Yazbi, Ahmed F, Eid, Ali H

“…Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell…”
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Role of diabetes in lung injury from acute exposure to electronic cigarette, heated tobacco product, and combustible cigarette aerosols in an animal model by Daou, Michella Abi Zeid, Shihadeh, Alan, Hashem, Yasmine, Bitar, Hala, Kassir, Alaa, El-Harakeh, Mohammad, Karaoghlanian, Nareg, Eid, Assaad A, El-Sabban, Marwan, Zaatari, Ghazi, Husari, Ahmad

“…Patients with diabetes are more vulnerable to the detrimental respiratory effects of combustible cigarette smoke (CS) when compared to the general population…”
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Podocyturia: an earlier biomarker of cardiovascular outcomes by Eid, Assaad A., Habib, Robert H., Chehab, Omar, Al Jalbout, Nour, Tamim, Hani, Makki, Maha, El Bejjani, Martine, Lima, Joao, Badr, Kamal F.

“…Urinary podocin and nephrin mRNAs (podocyturia), as candidate biomarkers of endothelial/podocyte injury, were measured by quantitative PCR in Type II diabetics…”
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The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus by Abi Akar, Elias, Weill, Laure, El Khoury, Mirella, Caradeuc, Cédric, Bertho, Gildas, Boutary, Suzan, Bezier, Cynthia, Clerc, Zoé, Sapaly, Delphine, Bendris, Sabrina, Cheguillaume, Flore, Giraud, Nicolas, Eid, Assaad A, Charbonnier, Frédéric, Biondi, Olivier

“…Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that commonly results from a high-calorie diet and sedentary lifestyle, leading to insulin…”
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Infection with Helicobacter pylori may predispose to atherosclerosis: role of inflammation and thickening of intima-media of carotid arteries by Aramouni, Karl, Assaf, Roland K., Azar, Maria, Jabbour, Karen, Shaito, Abdullah, Sahebkar, Amirhossein, Eid, Assaad A., Rizzo, Manfredi, Eid, Ali H.

“…Atherosclerosis is a major instigator of cardiovascular disease (CVD) and a main cause of global morbidity and mortality. The high prevalence of CVD calls for…”
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Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes by Maalouf, Rita M, Eid, Assaad A, Gorin, Yves C, Block, Karen, Escobar, Gladys Patricia, Bailey, Steven, Abboud, Hanna E

“…Oxidative stress contributes to diabetic cardiomyopathy. This study explored the role of the NADPH oxidase Nox4 as a source of reactive oxygen species (ROS)…”
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Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production by Fitzgerald, John P, Nayak, Bijaya, Shanmugasundaram, Karthigayan, Friedrichs, William, Sudarshan, Sunil, Eid, Assaad A, DeNapoli, Thomas, Parekh, Dipen J, Gorin, Yves, Block, Karen

“…Inflammatory cytokines are detected in the plasma of patients with renal cell carcinoma (RCC) and are associated with poor prognosis. However, the primary cell…”
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CYP450 Mediates Reactive Oxygen Species Production in a Mouse Model of β-Thalassemia through an Increase in 20-HETE Activity by Bou-Fakhredin, Rayan, Dia, Batoul, Ghadieh, Hilda E, Rivella, Stefano, Cappellini, Maria Domenica, Eid, Assaad A, Taher, Ali T

“…Oxidative damage by reactive oxygen species (ROS) is one of the main contributors to cell injury and tissue damage in thalassemia patients. Recent studies…”
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NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy by El Khoury, Mirella, Biondi, Olivier, Bruneteau, Gaelle, Sapaly, Delphine, Bendris, Sabrina, Bezier, Cynthia, Clerc, Zoé, Akar, Elias Abi, Weill, Laure, Eid, Assaad A., Charbonnier, Frédéric

“…Introduction Spinal muscular atrophy (SMA) is a fatal neurodegenerative disorder, characterized by motor neuron (MN) degeneration and severe muscular atrophy…”
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Translational Aspects of Sphingolipid Metabolism in Renal Disorders by Abou Daher, Alaa, El Jalkh, Tatiana, Eid, Assaad A, Fornoni, Alessia, Marples, Brian, Zeidan, Youssef H

“…Sphingolipids, long thought to be passive components of biological membranes with merely a structural role, have proved throughout the past decade to be major…”
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