Search Results - "Eid, Assaad"
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1
Role of AMPK/mTOR, mitochondria, and ROS in the pathogenesis of endometriosis
Published in Life sciences (1973) (01-10-2022)“…Endometriosis is the presence of endometrial tissue outside the uterine cavity usually in the ovaries, fallopian tube, and pelvic cavity. It's a chronic…”
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2
Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against…”
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3
Gut microbiota and mTOR signaling: Insight on a new pathophysiological interaction
Published in Microbial pathogenesis (01-05-2018)“…The gut microbiota plays a substantial role in regulating the host metabolic and immune functions. Dysbiosis, resulting from disruption of gut microbiota,…”
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4
556-P: 20-Hydroxyeicosatetraenoic Acid: A Prospective Therapeutic Target for Diabetes-Induced Neuropathy
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Background: Diabetic Neuropathy is one of the most prevalent complications of diabetes. Clinically, Diabetic Peripheral Neuropathy (DPN) is characterized by…”
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5
Butyrate modulates diabetes-linked gut dysbiosis: epigenetic and mechanistic modifications
Published in Journal of molecular endocrinology (01-01-2020)“…Diabetic dysbiosis has been described as a novel key player in diabetes and diabetic complications. However, the cellular/molecular alterations associated with…”
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Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression
Published in Molecular and Cellular Biology (01-09-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Translational Aspects of Sphingolipid Metabolism in Renal Disorders
Published in International journal of molecular sciences (25-11-2017)“…Sphingolipids, long thought to be passive components of biological membranes with merely a structural role, have proved throughout the past decade to be major…”
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8
NETosis contributes to the pathogenesis of diabetes and its complications
Published in Journal of molecular endocrinology (01-11-2020)“…NETosis, a novel form of neutrophil-related cell death, acts as a major regulator of diabetes and diabetes-associated complications. In this review, we show…”
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Role of diabetes in lung injury from acute exposure to electronic cigarette, heated tobacco product, and combustible cigarette aerosols in an animal model
Published in PloS one (10-08-2021)“…Patients with diabetes are more vulnerable to the detrimental respiratory effects of combustible cigarette smoke (CS) when compared to the general population…”
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10
Obstructive sleep apnea: Beyond the dogma of obesity
Published in Respiratory medicine (01-02-2024)“…Obstructive sleep apnea (OSA) has long been studied in patients with obesity and type 2 diabetes mellitus (T2DM), due to the fact that both disorders are…”
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11
COVID-19 and diabetes mellitus: how one pandemic worsens the other
Published in Reviews in endocrine & metabolic disorders (01-12-2020)“…In light of the most challenging public health crisis of modern history, COVID-19 mortality continues to rise at an alarming rate. Patients with co-morbidities…”
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12
Wireless Continuous Glucose Monitoring Using V-Band Circularly Polarized Directive Antenna Arrays in a Transmit/Receive System
Published in IEEE transactions on antennas and propagation (01-09-2024)“…This article discusses the design of circularly polarized V-band antenna arrays for continuous and wireless blood glucose monitoring. The proposed system is…”
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13
AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
Published in The Journal of biological chemistry (26-11-2010)“…Diabetes and high glucose (HG) increase the generation of NADPH oxidase-derived reactive oxygen species and induce apoptosis of glomerular epithelial cells…”
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14
Immune checkpoint inhibitors and diabetes: Mechanisms and predictors
Published in Diabetes & metabolism (01-05-2021)“…The emergence of immune checkpoint inhibitors in the arsenal of cancer immunotherapy was a breakthrough which provided hope to many cancer patients. However,…”
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15
Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production
Published in PloS one (27-01-2012)“…Inflammatory cytokines are detected in the plasma of patients with renal cell carcinoma (RCC) and are associated with poor prognosis. However, the primary cell…”
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16
Wearable flexible body matched electromagnetic sensors for personalized non-invasive glucose monitoring
Published in Scientific reports (01-09-2022)“…This work introduces novel body-matched, vasculature-inspired, quasi-antenna-arrays that act as electromagnetic sensors to instantaneously, continuously, and…”
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17
Immune Checkpoint Inhibitor-Induced Diabetes Mellitus: Potential Role of T Cells in the Underlying Mechanism
Published in International journal of molecular sciences (20-02-2021)“…Immunotherapy is now a recognized treatment option for several types of cancer. However, some cancer patients treated with immune checkpoint inhibitors (ICIs)…”
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18
Noninvasive, wearable, and tunable electromagnetic multisensing system for continuous glucose monitoring, mimicking vasculature anatomy
Published in Science advances (01-06-2020)“…Painless, needle-free, and continuous glucose monitoring sensors are needed to enhance the life quality of diabetic patients. To that extent, we propose a…”
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CYP450 Mediates Reactive Oxygen Species Production in a Mouse Model of β-Thalassemia through an Increase in 20-HETE Activity
Published in International journal of molecular sciences (23-01-2021)“…Oxidative damage by reactive oxygen species (ROS) is one of the main contributors to cell injury and tissue damage in thalassemia patients. Recent studies…”
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Translational Aspects of the Mammalian Target of Rapamycin Complexes in Diabetic Nephropathy
Published in Antioxidants & redox signaling (01-10-2022)“…Despite the many efforts put into understanding diabetic nephropathy (DN), direct treatments for DN have yet to be discovered. Understanding the mechanisms…”
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