Search Results - "Eichin, Felix"

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    Polyploidy control in hepatic health and disease by Sladky, Valentina C., Eichin, Felix, Reiberger, Thomas, Villunger, Andreas

    Published in Journal of hepatology (01-11-2021)
    “…A balanced increase in DNA content (ploidy) is observed in some human cell types, including bone-resorbing osteoclasts, platelet-producing megakaryocytes,…”
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    Journal Article
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    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts by Hutter, Katharina, Lohmüller, Michael, Jukic, Almina, Eichin, Felix, Avci, Seymen, Labi, Verena, Szabo, Tamas G., Hoser, Simon M., Hüttenhofer, Alexander, Villunger, Andreas, Herzog, Sebastian

    Published in Molecular cell (04-06-2020)
    “…Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved…”
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    Journal Article
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    Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy by Karbon, Gerlinde, Schuler, Fabian, Braun, Vincent Z, Eichin, Felix, Haschka, Manuel, Drach, Mathias, Sotillo, Rocio, Geley, Stephan, Spierings, Diana CJ, Tijhuis, Andrea E, Foijer, Floris, Villunger, Andreas

    Published in EMBO reports (12-06-2024)
    “…Interference with microtubule dynamics in mitosis activates the spindle assembly checkpoint (SAC) to prevent chromosome segregation errors. The SAC induces…”
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    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis by Kim, Ju Youn, Wang, Lily Q., Sladky, Valentina C., Oh, Tae Gyu, Liu, Junlai, Trinh, Kaitlyn, Eichin, Felix, Downes, Michael, Hosseini, Mojgan, Jacotot, Etienne D., Evans, Ronald M., Villunger, Andreas, Karin, Michael

    Published in Cell metabolism (04-10-2022)
    “…Sterol deficiency triggers SCAP-mediated SREBP activation, whereas hypernutrition together with ER-stress activate SREBP1/2 via caspase-2. Whether these…”
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    Journal Article
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