Search Results - "Eichhorn, D"
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Visualizing a two-state conformational ensemble in stem–loop 3 of the transcriptional regulator 7SK RNA
Published in Nucleic acids research (25-01-2024)“…Abstract Structural plasticity is integral to RNA function; however, there are currently few methods to quantitatively resolve RNAs that have multiple…”
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2
Structural determinants for ligand capture by a class II preQ₁ riboswitch
Published in Proceedings of the National Academy of Sciences - PNAS (11-02-2014)“…Prequeuosine (preQ ₁) riboswitches are RNA regulatory elements located in the 5′ UTR of genes involved in the biosynthesis and transport of preQ ₁, a precursor…”
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3
Postpartum development of metabolic dysfunction-associated steatotic liver disease in a lean mouse model of gestational diabetes mellitus
Published in Scientific reports (25-06-2024)“…Gestational diabetes mellitus (GDM) is associated with increased postpartum risk for metabolic dysfunction-associated steatotic liver disease (MASLD)…”
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4
Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy
Published in Nature methods (01-11-2011)“…In this Review, the authors thoroughly discuss solution-state NMR spectroscopy methods used for characterizing the dynamic structure landscape of RNA…”
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5
Structure and function of preQ1 riboswitches
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-10-2014)“…PreQ1 riboswitches help regulate the biosynthesis and transport of preQ1 (7-aminomethyl-7-deazaguanine), a precursor of the hypermodified guanine nucleotide…”
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6
Progress in 7SK ribonucleoprotein structural biology
Published in Frontiers in molecular biosciences (27-03-2023)“…The 7SK ribonucleoprotein (RNP) is a dynamic and multifunctional regulator of RNA Polymerase II (RNAPII) transcription in metazoa. Comprised of the non-coding…”
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7
Short and long-term effects of sham-controlled prefrontal EEG-neurofeedback training in healthy subjects
Published in Clinical neurophysiology (01-04-2016)“…Highlights • Controlled EEG neurofeedback study in adult healthy subjects using a novel sham design. • Altered frontal beta activity in healthy subjects after…”
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8
hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA
Published in Nucleic acids research (26-09-2016)“…The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and inactivates the positive transcription elongation factor b (P-TEFb), an essential eukaryotic…”
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9
Structure, Physical, and Photophysical Properties of Platinum(II) Complexes Containing Bidentate Aromatic and Bis(diphenylphosphino)methane as Ligands
Published in Inorganic chemistry (01-05-2000)“…This study focuses on a series of PtII(L−L‘)(dppm) n + complexes, where dppm is bis(diphenylphosphino)methane and L−L‘ are C∧C‘ (n = 0), C∧N (n = 1), and N∧N‘…”
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10
Identification and Biosynthetic Study of the Siderophore Lysochelin in the Biocontrol Agent Lysobacter enzymogenes
Published in Journal of agricultural and food chemistry (17-05-2023)“…Lysobacter is a genus of bacteria emerging as new biocontrol agents in agriculture. Although iron acquisition is essential for the bacteria, no siderophore has…”
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11
Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2018)“…The La and the La-related protein (LARP) superfamily is a diverse class of RNA binding proteins involved in RNA processing, folding, and function. Larp7 binds…”
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12
Structural basis of 7SK RNA 5′-γ-phosphate methylation and retention by MePCE
Published in Nature chemical biology (01-02-2019)“…Among RNA 5′-cap structures, γ-phosphate monomethylation is unique to a small subset of noncoding RNAs, 7SK and U6 in humans. 7SK is capped by methylphosphate…”
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13
C-terminal determinants for RNA binding motif 7 protein stability and RNA recognition
Published in Biophysical chemistry (01-01-2023)“…The 7SK ribonucleoprotein (RNP) is a critical regulator of eukaryotic transcription. Recently, RNA binding motif 7 (RBM7) containing an RNA recognition motif…”
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14
Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP
Published in Molecular cell (05-05-2022)“…7SK non-coding RNA (7SK) negatively regulates RNA polymerase II (RNA Pol II) elongation by inhibiting positive transcription elongation factor b (P-TEFb), and…”
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15
Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP
Published in Biophysical journal (10-02-2023)Get full text
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16
Structure of LARP7 Protein p65–telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR
Published in Journal of molecular biology (01-06-2023)“…[Display omitted] •Structure of LARP7 p65 bound to telomerase RNA in telomerase solved by cryoEM and NMR.•p65 interacts extensively with and refolds TER for…”
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Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins
Published in RNA biology (03-08-2021)“…La-related proteins 7 (LARP7) are a class of RNA chaperones that bind the 3′ ends of RNA and are constitutively associated with their specific target RNAs. In…”
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18
Do families want to be present during CPR? A retrospective survey
Published in Journal of emergency nursing (01-10-1998)“…Introduction The purpose of this study was to interview families who had experienced the death of a loved one to determine their desires, beliefs, and concerns…”
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Family presence during invasive procedures and resuscitation
Published in The American journal of nursing (01-02-2000)“…Meyers et al describe a study that examined the effects of family presence during invasive procedures and resuscitation on the family, patient, nurses and…”
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Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure
Published in Nucleic acids research (01-12-2013)“…Riboswitches are structural elements in the 5' untranslated regions of many bacterial messenger RNAs that regulate gene expression in response to changing…”
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