Search Results - "Eicher, Thomas"
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Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2012)“…AcrAB-TolC is the major efflux protein complex in Escherichia coli extruding a vast variety of antimicrobial agents from the cell. The inner membrane component…”
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Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
Published in eLife (19-09-2014)“…Membrane transporters of the RND superfamily confer multidrug resistance to pathogenic bacteria, and are essential for cholesterol metabolism and embryonic…”
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Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism
Published in Science (American Association for the Advancement of Science) (01-09-2006)“…The AcrA/AcrB/TolC complex spans the inner and outer membranes of Escherichia coli and serves as its major drug-resistance pump. Driven by the proton motive…”
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Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB
Published in Nature structural & molecular biology (01-02-2008)“…The AcrA–AcrB–TolC complex is the major multidrug efflux pump in Escherichia coli . The asymmetric structure of the trimeric inner-membrane component AcrB…”
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The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance
Published in Current drug targets (01-09-2008)“…Antimicrobial resistance of human pathogenic bacteria is an emerging problem for global public health. This resistance is often associated with the…”
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Analysis of AcrB and AcrB/DARPin ligand complexes by LILBID MS
Published in Biochimica et biophysica acta (01-09-2011)“…The AcrA/AcrB/TolC complex is responsible for intrinsic multidrug resistance (MDR) in Escherichia coli. Together with the periplasmic adaptor protein AcrA and…”
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Structural and functional aspects of the multidrug efflux pump AcrB
Published in Biological chemistry (01-08-2009)“…The tripartite efflux system AcrA/AcrB/TolC is the main pump in Escherichia coli for the efflux of multiple antibiotics, dyes, bile salts and detergents. The…”
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Mit Einem Blick das Ganze Panorama des Grandiosen Platzes: Panoramatische Strukturen in Des Vetters Eckfenster von E.T.A. Hoffmann
Published in Poetica (München) (14-08-1993)Get full text
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Mit Einem Blick das Ganze Panorama des Grandiosen Platzes
Published in Poetica (München) (01-08-1993)Get full text
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"Back Again in the Mill". Zur Symbolik der Kreisform in James Joyces "Two Gallants"
Published in Neophilologus (01-01-1993)Get full text
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Kritik der Interpretation: Analytische Untersuchungen zu interpretationskritischen Literaturtheorien
Published in The German quarterly (1997)Get full text
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Erzahlte Visualitat: Studien zum Verhaltnis von Text und Bild in Hermann Brochs Romantrilogie "Die Schlafwandler"
Published in The German quarterly (1994)Get full text
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MIT EINEM BLICK DAS GANZE PANORAMA DES GRANDIOSEN PLATZES“. Panoramatische Strukturen in "Des Vetters Eckfenster" von E.T.A. Hoffmann
Published in Poetica (München) (01-01-1993)Get full text
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Alexander Lernet-Holenia, Die Lust an der Ungleichzeitigkeit (Book Review)
Published in Modern Austrian Literature (01-01-1999)Get full text
Book Review -
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Back again in the mill». Zur Symbolik der Kreisform in James Joyces «Two Gallants
Published in Neophilologus (01-04-1993)Get full text
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Erzählte Visualität: Studien zum Verhältnis von Text und Bild in Hermann Brochs Romantrilogie "Die Schlafwandler"
Published in German Studies Review (01-02-1995)Get full text
Book Review Journal Article -
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Phantom Empires: The Novels of Alexander Lernet-Holenia and the Question of Postimperial Austrian Identity
Published in Monatshefte (01-04-1998)Get full text
Book Review -
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Kritik der Interpretation: Analytische Untersuchungen zu interpretationskritischen Literaturtheorien
Published in The German Quarterly (01-07-1997)Get full text
Book Review -
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Die Lust an der Ungleichzeitigkeit
Published in Modern Austrian Literature (01-01-1999)Get full text
Book Review -
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"Auf dämmernden Fluten... unbekannten Zielen entgegen." Die Ägidius-Dichtung Heinrich Bermanns in Arthur Schnitzlers "Der Weg ins Freie"
Published in Modern Austrian literature (01-01-1992)Get full text
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