Search Results - "Eichberg, Michael J."

Lessons Learned from the Development and Roll-Out of the rVSVΔG-ZEBOV-GP Zaire ebolavirus Vaccine to Inform Marburg Virus and Sudan ebolavirus Vaccines by Coller, Beth-Ann G., Lapps, William, Yunus, Mahum, Bruno, Samantha, Eichberg, Michael J., Lee, Andrew Wen-Tseng, Liu, Kenneth, Drury, Rosybel, Millogo, Jules, Macareo, Louis Robert, Armstrong, Thomas H., Blue, Jeffrey T., Isopi, Lynne A., Hughes, Melissa, VanRheenen, Susan M., Deutsch, Jonathan, Tell, Joan G., Dubey, Sheri A.

“…This review describes key aspects of the development of the rVSVΔG-ZEBOV-GP Ebola vaccine and key activities which are continuing to further expand our…”
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Cobalt-Mediated [2+2+2] Cycloaddition versus CH and NH Activation of Pyridones and Pyrazinones with Alkynes: An Experimental Study by Aubert, Corinne, Betschmann, Patrick, Eichberg, Michael J., Gandon, Vincent, Heckrodt, Thilo J., Lehmann, Jürg, Malacria, Max, Masjost, Birgit, Paredes, Elisa, Vollhardt, K. Peter C., Whitener, Glenn D.

“…The reactivity of a range of pyridone and pyrazinone derivatives towards alkynes in the presence of cyclopentadienylcobaltbis(ethene) has been investigated…”
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Approaches to the Synthesis of (±)-Strychnine via the Cobalt-Mediated [2 + 2 + 2] Cycloaddition:  Rapid Assembly of a Classic Framework by Eichberg, Michael J, Dorta, Rosa L, Grotjahn, Douglas B, Lamottke, Kai, Schmidt, Martin, Vollhardt, K. Peter C

“…Five synthetic approaches to racemic strychnine (1), with the cobalt-mediated [2 + 2 + 2] cycloaddition of alkynes to indoles as the key step, are described…”
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The Thermal Retro[2+2+2]cycloaddition of Cyclohexane Activated by Triscyclobutenannelation: Concerted All-Disrotatory versus Stepwise Conrotatory Pathways to Fused [12]Annulenes by Eichberg, Michael J., Houk, K. N., Lehmann, Jürg, Leonard, Philip W., Märker, Anne, Norton, Joseph E., Sawicka, Dorota, Vollhardt, K. Peter C., Whitener, Glenn D., Wolff, Stefan

“…All dis or all con? While benzo analogues 2–4 undergo cycloreversion of the central cyclohexane ring by all‐disrotatory opening, the triscyclobutenocyclohexane…”
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Public funding of clinical-stage antibiotic development in the United States and European Union by Eichberg, Michael J

“…The health and national security challenge of antibiotic resistance has led governments to adopt policies to stimulate new antibiotic R&D. Government programs…”
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The Formal Total Synthesis of (±)-Strychnine via a Cobalt-Mediated [2 + 2 + 2]Cycloaddition by Eichberg, Michael J, Dorta, Rosa L, Lamottke, Kai, Vollhardt, K. Peter C

“…A short, highly convergent total synthesis of racemic isostrychnine, and thus strychnine, has been completed. The route involves 14 steps in the longest linear…”
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Synthesis, Structure, and Fluxionality of (μ-Diphenylsilylene)(fulvalene)tetracarbonyldirhenium Double Si−H Activation to the First Fulvalene Silylene Complex by Kayser, Bernd, Eichberg, Michael J, Vollhardt, K. Peter C

“…(Fulvalene)hexacarbonyldirhenium (1) furnishes the first silylene fulvalenedimetal complex 3 by double Si−H activation. The solid-state structure of the…”
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Photosubstitution of (Fulvalene)tetracarbonyldiruthenium by Alkenes and Alkynes:  First Observation of Alkyne Coupling on Fulvalene Dimetals and Synthesis of a (Fulvalene)dimetallacyclopentadiene(alkene) Complex by Chen, Ming-Chou, Eichberg, Michael J, Vollhardt, K. Peter C, Sercheli, Ricardo, Wasser, Ian M, Whitener, Glenn D

“…Irradiation (λmax = 300−375 nm) of FvRu2(CO)4 (1, Fv = η5:η5-bicyclopentadienyl) or (μ2-η1:η5-cyclopentadienyl)2Ru2(CO)4 (2) with dimethyl cis- or…”
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Lessons Learned from the Development and Roll-Out of the rVSVΔG-ZEBOV-GP IZaire ebolavirus/I Vaccine to Inform Marburg Virus and ISudan ebolavirus/I Vaccines by Coller, Beth-Ann G, Lapps, William, Yunus, Mahum, Bruno, Samantha, Eichberg, Michael J, Lee, Andrew Wen-Tseng, Liu, Kenneth, Drury, Rosybel, Millogo, Jules, Macareo, Louis Robert, Armstrong, Thomas H, Blue, Jeffrey T, Isopi, Lynne A, Hughes, Melissa, VanRheenen, Susan M, Deutsch, Jonathan, Tell, Joan G, Dubey, Sheri A

“…This review describes key aspects of the development of the rVSVΔG-ZEBOV-GP Ebola vaccine and key activities which are continuing to further expand our…”
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Radial (tetracyclopentadienyl)cyclobutadiene pentametals by Eichberg, Michael J., Kayser, Bernd, Leonard, Philip W., Miljanić, Ognjen Š., Timofeeva, Tatiana V., Vollhardt, K. Peter C., Whitener, Glenn D., Yakovenko, Andrey, Yu, Yong

“…Radial (tetracyclopentadienyl)cyclobutadiene pentametals have been synthesized by the Pd-catalyzed coupling of cyclopentadienyltin or of (CpM)zinc reagents…”
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The Thermal Retro[2+2+2]cycloaddition of Cyclohexane Activated by Triscyclobutenannelation: Concerted All-Disrotatory versus Stepwise Conrotatory Pathways to Fused [12]Annulenes by Eichberg, Michael J., Houk, K. N., Lehmann, Jürg, Leonard, Philip W., Märker, Anne, Norton, Joseph E., Sawicka, Dorota, Vollhardt, K. Peter C., Whitener, Glenn D., Wolff, Stefan

“…Alles dis‐ oder alles kon‐? In den Benzoderivaten 2–4 verläuft die Cycloreversion des mittleren Cyclohexanrings über eine all‐disrotatorische Ringöffnung,…”
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