Search Results - "Eich, R F"

Mechanism of NO-Induced Oxidation of Myoglobin and Hemoglobin by Eich, Raymund F, Li, Tiansheng, Lemon, Douglas D, Doherty, Daniel H, Curry, Shawn R, Aitken, Jacqueline F, Mathews, Antony J, Johnson, Kenneth A, Smith, Robert D, Phillips, George N, Olson, John S

“…Nitric oxide (NO) has been implicated as mediator in a variety of physiological functions, including neurotransmission, platelet aggregation, macrophage…”
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Reactions of sperm whale myoglobin with hydrogen peroxide. Effects of distal pocket mutations on the formation and stability of the ferryl intermediate by Alayash, A I, Ryan, B A, Eich, R F, Olson, J S, Cashon, R E

“…Distal pocket mutants of sperm whale oxymyoglobin (oxy-Mb) were reacted with a 2.5-fold excess of hydrogen peroxide (HOOH) in phosphate buffer at pH 7.0, 37…”
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A Cyanobacterial Hemoglobin with Unusual Ligand Binding Kinetics and Stability Properties by Thorsteinsson, Marc V, Bevan, David R, Potts, Malcolm, Dou, Yi, Eich, Raymund F, Hargrove, Mark S, Gibson, Quentin H, Olson, John S

“…The glbN gene of the cyanobacterium Nostoc commune UTEX 584 encodes a hemoprotein, named cyanoglobin, that has high oxygen affinity. The basis for the high…”
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A Double Mutant of Sperm Whale Myoglobin Mimics the Structure and Function of Elephant Myoglobin (∗) by Zhao, Xuefeng, Vyas, K., Nguyen, Bao D., Rajarathnam, Krishnakumar, Mar, Gerd N. La, Li, Tiansheng, Phillips, George N., Eich, Raymund F., Olson, John S., Ling, Jinshu, Bocian, David F.

“…The functional, spectral, and structural properties of elephant myoglobin and the L29F/H64Q mutant of sperm whale myoglobin have been compared in detail by…”
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Protein engineering strategies for designing more stable hemoglobin-based blood substitutes by Olson, J S, Eich, R F, Smith, L P, Warren, J J, Knowles, B C

“…Over the past five years our laboratory has been using rational, comparative, and random combinatorial mutagenesis strategies to optimize the alpha and beta…”
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Myoglobin as a model system for designing heme protein based blood substitutes by Dou, Yi, Maillett, David H, Eich, Raymund F, Olson, John S

“…The ligand binding properties and resistances to denaturation of >300 different site-directed mutants of sperm whale, pig, and human myoglobin have been…”
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Interactions among residues CD3, E7, E10, and E11 in myoglobins: Attempts to simulate the ligand-binding properties of Aplysia myoglobin by Smerdon, Stephen J, Krzywda, Szymon, Brzozowski, Andrzej M, Davies, Gideon J, Wilkinson, Anthony J, Brancaccio, Andrea, Cutruzzola, Francesca, Allocatelli, Carlo Travaglini, Brunori, Maurizio, Brantley, Robert E. Jr, Carver, Theodore E, Eich, Raymund F, Singleton, Eileen, Olson, John S

“…Site-directed mutations have been introduced singly and in combination at residues lysine/arginine45 (CD3), histidine64 (E7), threonine67 (E10), and valine68…”
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