Search Results - "Eibl, Dieter"

Plant cell culture technology in the cosmetics and food industries: current state and future trends by Eibl, Regine, Meier, Philipp, Stutz, Irène, Schildberger, David, Hühn, Tilo, Eibl, Dieter

“…The production of drugs, cosmetics, and food which are derived from plant cell and tissue cultures has a long tradition. The emerging trend of manufacturing…”
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Manufacturing human mesenchymal stem cells at clinical scale: process and regulatory challenges by Jossen, Valentin, van den Bos, Christian, Eibl, Regine, Eibl, Dieter

“…Human mesenchymal stem cell (hMSC)-based therapies are of increasing interest in the field of regenerative medicine. As economic considerations have shown,…”
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Disposable bioreactors: the current state-of-the-art and recommended applications in biotechnology by Eibl, Regine, Kaiser, Stephan, Lombriser, Renate, Eibl, Dieter

“…Disposable bioreactors have increasingly been incorporated into preclinical, clinical, and production-scale biotechnological facilities over the last few…”
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Food ingredients and food made with plant cell and tissue cultures: State‐of‐the art and future trends by Gubser, Geraldine, Vollenweider, Sabine, Eibl, Dieter, Eibl, Regine

“…Climate change and an increasing world population means traditional farming methods may not be able to meet the anticipated growth in food demands. Therefore,…”
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Design of bioreactors suitable for plant cell and tissue cultures by Eibl, Regine, Eibl, Dieter

“…Plant cell suspension cultures and hairy roots are potential sources of secondary metabolites and recombinant proteins. In contrast to traditionally grown…”
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An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes by Schirmer, Cedric, Maschke, Rüdiger W., Pörtner, Ralf, Eibl, Dieter

“…No matter the scale, stirred tank bioreactors are the most commonly used systems in biotechnological production processes. Single-use and reusable systems are…”
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Oxygen Mass Transfer in Biopharmaceutical Processes: Numerical and Experimental Approaches by Seidel, Stefan, Maschke, Rüdiger W., Werner, Sören, Jossen, Valentin, Eibl, Dieter

“…Oxygen supply in aerobic bioprocesses is of crucial importance. For this reason, this paper presents the oxygen demand of different cells and summarizes…”
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CFD modelling of a wave-mixed bioreactor with complex geometry and two degrees of freedom motion by Seidel, Stefan, Maschke, Rüdiger W., Kraume, Matthias, Eibl, Regine, Eibl, Dieter

“…Optimizing bioprocesses requires an in-depth understanding, from a bioengineering perspective, of the cultivation systems used. A bioengineering…”
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Improvement of HEK293 Cell Growth by Adapting Hydrodynamic Stress and Predicting Cell Aggregate Size Distribution by Seidel, Stefan, Maschke, Rüdiger W, Mozaffari, Fruhar, Eibl-Schindler, Regine, Eibl, Dieter

“…HEK293 is a widely used cell line in the fields of research and industry. It is assumed that these cells are sensitive to hydrodynamic stress. The aim of this…”
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Theoretical and Practical Issues That Are Relevant When Scaling Up hMSC Microcarrier Production Processes by Eibl, Dieter, Kraume, Matthias, Eibl, Regine, Mostafa Sindi, Dolman, Schirmer, Cedric, Jossen, Valentin, Pörtner, Ralf

“…The potential of human mesenchymal stem cells (hMSCs) for allogeneic cell therapies has created a large amount of interest. However, this presupposes the…”
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Improved Time Resolved KPI and Strain Characterization of Multiple Hosts in Shake Flasks Using Advanced Online Analytics and Data Science by Maschke, Rüdiger W, Pretzner, Barbara, John, Gernot T, Herwig, Christoph, Eibl, Dieter

“…Shake flasks remain one of the most widely used cultivation systems in biotechnology, especially for process development (cell line and parameter screening)…”
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Growth Behavior of Human Adipose Tissue-Derived Stromal/Stem Cells at Small Scale: Numerical and Experimental Investigations by Jossen, Valentin, Eibl, Regine, Kraume, Matthias, Eibl, Dieter

“…Human adipose tissue-derived stromal/stem cells (hASCs) are a valuable source of cells for clinical applications, especially in the field of regenerative…”
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Keeping SARS-CoV-2 out: Vaccines, Filters, and Self-disinfecting Textiles by Eibl, Dieter, Sievers, Martin, Eibl, Regine, Bachmann, Martin, Walton, Senta, Keel, Nik, Richner, Gilles, Stübinger, Stefan, Hirsch, Sven, Yeretzian, Chahan, Opitz, Sebastian E.W., Heldal, Trond, Adlhart, Christian

“…When the SARS-CoV-2 pandemic started,[1] science came to the immediate attention of the broad public. People and politicians were hanging on every word of…”
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An Approach for Scale-Up of Geometrically Dissimilar Orbitally Shaken Single-Use Bioreactors by Werner, Sören, Olownia, Johanna, Egger, Daniel, Eibl, Dieter

“…An initial approach for scaling up geometrically dissimilar orbitally shaken bioreactors is presented. A novel ShakerBag Option for Multitron Cell shaking…”
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Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution by Werner, Sören, Eibl, Regine, Lettenbauer, Christine, Röll, Marcel, Eibl, Dieter, De Jesus, Maria, Zhang, Xiaowei, Stettler, Matthieu, Tissot, Stephanie, Bürki, Cedric, Broccard, Gilles, Kühner, Markus, Tanner, Rolf, Baldi, Lucia, Hacker, David, Wurm, Florian M

“…Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to…”
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Single‐Use Technology in Biopharmaceutical Manufacture and Beyond by Eibl, Dieter, Eibl, Regine

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Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale by Demuth, Caspar, Varonier, Joel, Jossen, Valentin, Eibl, Regine, Eibl, Dieter

“…pH value and the concentration of dissolved oxygen (DO) are key parameters to monitor and control cell growth in cultivation studies. Reliable, robust and…”
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Chemically Defined, Xeno-Free Expansion of Human Mesenchymal Stem Cells (hMSCs) on Benchtop-Scale Using a Stirred Single-Use Bioreactor by Teale, Misha, Jossen, Valentin, Eibl, Dieter, Eibl, Regine

“…In recent years, the use of hMSCs, which may be isolated from adipose tissue among others, for the treatment of diseases has increased significantly. The cell…”
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Laboratory-independent exploration of stirred bioreactors and their fluid dynamics by Seidel, Stefan, Eibl-Schindler, Regine, Eibl, Dieter

“…Due to the steadily rising number of students and the simultaneous reduction in practical lessons in study programs, the need for alternative learning…”
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Determination of culture design spaces in shaken disposable cultivation systems for CHO suspension cell cultures by Maschke, Rüdiger W., Seidel, Stefan, Bley, Thomas, Eibl, Regine, Eibl, Dieter

“…Processes involving mammalian cell cultures - especially CHO suspension cells - dominate biopharmaceutical manufacturing. These processes are usually developed…”
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