Search Results - "Eibauer, Matthias"

The molecular architecture of lamins in somatic cells by Turgay, Yagmur, Eibauer, Matthias, Goldman, Anne E., Shimi, Takeshi, Khayat, Maayan, Ben-Harush, Kfir, Dubrovsky-Gaupp, Anna, Sapra, K. Tanuj, Goldman, Robert D., Medalia, Ohad

“…Cryo-electron tomography reveals a detailed view of the structural organization of the lamin meshwork within the lamina of the mammalian cell nucleus. The…”
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Structure and gating of the nuclear pore complex by Eibauer, Matthias, Pellanda, Mauro, Turgay, Yagmur, Dubrovsky, Anna, Wild, Annik, Medalia, Ohad

“…Nuclear pore complexes (NPCs) perforate the nuclear envelope and allow the exchange of macromolecules between the nucleus and the cytoplasm. To acquire a…”
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Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography by Rigort, Alexander, Bäuerlein, Felix J. B, Villa, Elizabeth, Eibauer, Matthias, Laugks, Tim, Baumeister, Wolfgang, Plitzko, Jürgen M

“…Cryoelectron tomography provides unprecedented insights into the macromolecular and supramolecular organization of cells in a close-to-living state. However…”
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Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy by Weber, Miriam S, Eibauer, Matthias, Sivagurunathan, Suganya, Magin, Thomas M, Goldman, Robert D, Medalia, Ohad

“…Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network…”
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Talin-activated vinculin interacts with branched actin networks to initiate bundles by Boujemaa-Paterski, Rajaa, Martins, Bruno, Eibauer, Matthias, Beales, Charlie T, Geiger, Benjamin, Medalia, Ohad

“…Vinculin plays a fundamental role in integrin-mediated cell adhesion. Activated by talin, it interacts with diverse adhesome components, enabling mechanical…”
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Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control by Schmid, Markus, Ernst, Patrick, Honegger, Annemarie, Suomalainen, Maarit, Zimmermann, Martina, Braun, Lukas, Stauffer, Sarah, Thom, Cristian, Dreier, Birgit, Eibauer, Matthias, Kipar, Anja, Vogel, Viola, Greber, Urs F., Medalia, Ohad, Plückthun, Andreas

“…Most systemic viral gene therapies have been limited by sequestration and degradation of virions, innate and adaptive immunity, and silencing of therapeutic…”
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Structural Analysis of Supramolecular Assemblies by Cryo-Electron Tomography by Harapin, Jan, Eibauer, Matthias, Medalia, Ohad

“…Structural analysis of macromolecular assemblies in their physiological environment is a challenging task that is instrumental in answering fundamental…”
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Filament assembly of the C. elegans lamin in the absence of helix 1A by de Leeuw, Rebecca, Kronenberg-Tenga, Rafael, Eibauer, Matthias, Medalia, Ohad

“…Lamins are the major constituent of the nuclear lamina, a protein meshwork underlying the inner nuclear membrane. Nuclear lamins are type V intermediate…”
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Micromachining tools and correlative approaches for cellular cryo-electron tomography by Rigort, Alexander, Bäuerlein, Felix J.B., Leis, Andrew, Gruska, Manuela, Hoffmann, Christian, Laugks, Tim, Böhm, Ulrike, Eibauer, Matthias, Gnaegi, Helmut, Baumeister, Wolfgang, Plitzko, Jürgen M.

“…A principal limitation of cryo-transmission electron microscopy performed on cells or tissues is the accessible specimen thickness. This is exacerbated in…”
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Structural analysis of receptors and actin polarity in platelet protrusions by Sorrentino, Simona, Conesa, Jose Javier, Cuervo, Ana, Melero, Roberto, Martins, Bruno, Fernandez-Gimenez, Estrella, P. de Isidro-Gomez, Federico, de la Morena, Jimenez, Studt, Jan-Dirk, Sorzano, Carlos Oscar S., Eibauer, Matthias, Carazo, Jose Maria, Medalia, Ohad

“…During activation the platelet cytoskeleton is reorganized, inducing adhesion to the extracellular matrix and cell spreading. These processes are critical for…”
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Structure and 3D Arrangement of Endoplasmic Reticulum Membrane-Associated Ribosomes by Pfeffer, Stefan, Brandt, Florian, Hrabe, Thomas, Lang, Sven, Eibauer, Matthias, Zimmermann, Richard, Förster, Friedrich

“…In eukaryotic cells, cotranslational protein translocation across the endoplasmic reticulum (ER) membrane requires an elaborate macromolecular machinery. While…”
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A network of mixed actin polarity in the leading edge of spreading cells by Chung, Wen-Lu, Eibauer, Matthias, Li, Wenhong, Boujemaa-Paterski, Rajaa, Geiger, Benjamin, Medalia, Ohad

“…Physical interactions of cells with the underlying extracellular matrix (ECM) play key roles in multiple cellular processes. The actin cytoskeleton is a…”
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The macromolecular architecture of platelet-derived microparticles by Tamir, Adi, Sorrentino, Simona, Motahedeh, Sarah, Shai, Ela, Dubrovsky, Anna, Dahan, Idit, Eibauer, Matthias, Studt, Jan-Dirk, Sapra, K. Tanuj, Varon, David, Medalia, Ohad

“…Platelets are essential for hemostasis and wound healing. They are involved in fundamental processes of vascular biology such as angiogenesis, tissue…”
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Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ by Ortiz, Julio O, Brandt, Florian, Matias, Valério R.F, Sennels, Lau, Rappsilber, Juri, Scheres, Sjors H.W, Eibauer, Matthias, Hartl, F. Ulrich, Baumeister, Wolfgang

“…Ribosomes arranged in pairs (100S) have been related with nutritional stress response and are believed to represent a "hibernation state." Several proteins…”
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Marker-free image registration of electron tomography tilt-series by Sorzano, Carlos Oscar Sanchez, Messaoudi, Cédric, Eibauer, Matthias, Bilbao-Castro, J R, Hegerl, R, Nickell, S, Marco, S, Carazo, J M

“…Tilt series are commonly used in electron tomography as a means of collecting three-dimensional information from two-dimensional projections. A common problem…”
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Structural determinants of intermediate filament mechanics by Kechagia, Zanetta, Eibauer, Matthias, Medalia, Ohad

“…Intermediate filaments (IFs) are integral to the cell cytoskeleton, supporting cellular mechanical stability. Unlike other cytoskeletal components, the…”
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Unveiling the polarity of actin filaments by cryo-electron tomography by Martins, Bruno, Sorrentino, Simona, Chung, Wen-Lu, Tatli, Meltem, Medalia, Ohad, Eibauer, Matthias

“…The actin cytoskeleton plays a fundamental role in numerous cellular processes, such as cell motility, cytokinesis, and adhesion to the extracellular matrix…”
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A lamin A/C variant causing striated muscle disease provides insights into filament organization by Kronenberg-Tenga, Rafael, Tatli, Meltem, Eibauer, Matthias, Wu, Wei, Shin, Ji-Yeon, Bonne, Gisèle, Worman, Howard J, Medalia, Ohad

“…The gene encodes the A-type lamins, which polymerize into ∼3.5-nm-thick filaments and, together with B-type lamins and associated proteins, form the nuclear…”
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Vimentin filaments integrate low-complexity domains in a complex helical structure by Eibauer, Matthias, Weber, Miriam S., Kronenberg-Tenga, Rafael, Beales, Charlie T., Boujemaa-Paterski, Rajaa, Turgay, Yagmur, Sivagurunathan, Suganya, Kraxner, Julia, Köster, Sarah, Goldman, Robert D., Medalia, Ohad

“…Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells with tissue-specific mechanical properties and are involved in…”
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Insights into the gate of the nuclear pore complex by Zwerger, Monika, Eibauer, Matthias, Medalia, Ohad

“…Nuclear pore complexes (NPCs) serve as the gateway of the cell nucleus. These macromolecular assemblies form selective aqueous translocation channels…”
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