Search Results - "Ehrhart, E. J"

Histological and mechanical comparisons of arytenoid cartilage between 4 brachycephalic and 8 non-brachycephalic dogs: A pilot study by Tokunaga, Satoshi, Ehrhart, E. J, Monnet, Eric

“…Brachycephalic airway syndrome (BAS) is a well-established cause of respiratory distress in dogs. BAS without surgical correction results in eventual laryngeal…”
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Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients by Wong, Shukmei, Ehrhart, E. J, Stewart, Samuel, Zismann, Victoria, Cawley, Jacob, Halperin, Rebecca, Briones, Natalia, Richter, Keith, Sivaprakasam, Karthigayini, Perdigones, Nieves, Contente-Cuomo, Tania, Facista, Salvatore, Trent, Jeffrey M, Murtaza, Muhammed, Khanna, Chand, Hendricks, William P. D

“…Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer’s clinical management. Variation in driver…”
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Classification of Canine Malignant Lymphomas According to the World Health Organization Criteria by Valli, V. E., Myint, M. San, Barthel, A., Bienzle, D., Caswell, J., Colbatzky, F., Durham, A., Ehrhart, E. J., Johnson, Y., Jones, C., Kiupel, M., Labelle, P., Lester, S., Miller, M., Moore, P., Moroff, S., Roccabianca, P., Ramos-Vara, J., Ross, A., Scase, T., Tvedten, H., Vernau, W.

“…A study was carried out to test the accuracy and consistency of veterinary pathologists, not specialists in hematopathology, in applying the World Health…”
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Polymerase chain reaction for antigen receptor rearrangement: Benchmarking performance of a lymphoid clonality assay in diverse canine sample types by Ehrhart, E. J., Wong, Shukmei, Richter, Keith, Zismann, Victoria, Grimes, Carolyn, Hendricks, William, Khanna, Chand

“…Background Polymerase chain reaction for antigen receptor rearrangement (PARR) is a molecular diagnostic tool used for discrimination of lymphoid malignancies…”
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A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model by Saba, Corey, Paoloni, Melissa, Mazcko, Christina, Kisseberth, William, Burton, Jenna H, Smith, Annette, Wilson-Robles, Heather, Allstadt, Sara, Vail, David, Henry, Carolyn, Lana, Susan, Ehrhart, E J, Charles, Brad, Kent, Michael, Lawrence, Jessica, Burgess, Kristine, Borgatti, Antonella, Suter, Steve, Woods, Paul, Gordon, Ira, Vrignaud, Patricia, Khanna, Chand, LeBlanc, Amy K

“…Development of iniparib as an anti-cancer agent was hindered in part by lingering questions regarding its mechanism of action, the activity of its metabolites,…”
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Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials by Paoloni, Melissa, Webb, Craig, Mazcko, Christina, Cherba, David, Hendricks, William, Lana, Susan, Ehrhart, E J, Charles, Brad, Fehling, Heather, Kumar, Leena, Vail, David, Henson, Michael, Childress, Michael, Kitchell, Barbara, Kingsley, Christopher, Kim, Seungchan, Neff, Mark, Davis, Barbara, Khanna, Chand, Trent, Jeffrey

“…Molecularly-guided trials (i.e. PMed) now seek to aid clinical decision-making by matching cancer targets with therapeutic options. Progress has been hampered…”
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Suggested guidelines for immunohistochemical techniques in veterinary diagnostic laboratories by Ramos-Vara, J.A, Kiupel, M, Baszler, T, Bliven, L, Brodersen, B, Chelack, B, Czub, S, Del Piero, F, Dial, S, Ehrhart, E.J

“…Correspondence: 1 Corresponding Author: José A. Ramos-Vara, Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN…”
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Expression and Function of Survivin in Canine Osteosarcoma by SHOENEMAN, Jenette K, EHRHART, E. J, EICKHOFF, Jens C, CHARLES, J. B, POWERS, Barbara E, THAMM, Douglas H

“…Osteosarcoma has a high mortality rate and remains in need of more effective therapeutic approaches. Survivin is an inhibitor of apoptosis family member…”
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Combination Therapy with Zoledronic Acid and Parathyroid Hormone Improves Bone Architecture and Strength following a Clinically-Relevant Dose of Stereotactic Radiation Therapy for the Local Treatment of Canine Osteosarcoma in Athymic Rats by Curtis, Ryan C, Custis, James T, Ehrhart, Nicole P, Ehrhart, E J, Condon, Keith W, Gookin, Sara E, Donahue, Seth W

“…Clinical studies using definitive-intent stereotactic radiation therapy (SRT) for the local treatment of canine osteosarcoma (OSA) have shown canine patients…”
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The Comparative Diagnostic Features of Canine and Human Lymphoma by Seelig, Davis M, Avery, Anne C, Ehrhart, E J, Linden, Michael A

“…The non-Hodgkin lymphomas (NHLs) are a heterogeneous family of lymphoid malignancies that are among the most common neoplasms of both dogs and humans. Owing to…”
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DOG1 is a sensitive and specific immunohistochemical marker for diagnosis of canine gastrointestinal stromal tumors by Dailey, Deanna D., Ehrhart, E. J., Duval, Dawn L., Bass, Todd, Powers, B. E.

“…Gastrointestinal stromal tumors (GISTs) and leiomyosarcomas are histologically similar primary neoplasms commonly occurring in the gastrointestinal tract of…”
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Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine by Thamm, Douglas H., Weishaar, Kristen M., Charles, Joseph B., Ehrhart, E. J.

“…Canine cutaneous mast cell tumour (MCT) is the most common malignant skin tumour in dogs and can exhibit variable biologic behaviour. Dysregulated signalling…”
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Prospective evaluation of flow cytometric characteristics, histopathologic diagnosis and clinical outcome in dogs with naïve B‐cell lymphoma treated with a 19‐week CHOP protocol by Wolf‐Ringwall, Amber, Lopez, Lynelle, Elmslie, Robyn, Fowler, Brooke, Lori, Janet, Sfiligoi, Gabriella, Skope, Anne, Arnold, Erin, Hughes, Kelly L., Thamm, Douglas H., Ehrhart, E. J., Avery, Anne C., Lana, Susan E.

“…Canine B‐cell lymphoma is a clinically heterogenous disease; however, it is generally treated as a single disease entity. The purpose of this clinical trial…”
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Preclinical Investigation of PEGylated Tumor Necrosis Factor α in Dogs with Spontaneous Tumors: Phase I Evaluation by THAMM, Douglas H, KURZMAN, Ilene D, CLARK, Mike A, EHRHART, E. J, KRAFT, Susan L, GUSTAFSON, Daniel L, VAIL, David M

“…Tumor necrosis factor-alpha (TNF) is a cytokine with potent antitumor activity; however, toxicity and short half-life have limited its utility. Polyethylene…”
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Unfolding the diagnosis of subspectacular fluid opacity in a corn snake (Pantherophis guttatus) by Cleymaet, Allison M., Ehrhart, EJ, Sadar, Miranda J., Johnston, Matthew, Wotman, Kathryn, Linde Henriksen, Michala

“…Objective To present the results of clinical, surgical, and histopathologic procedures and how these were compared with the initial presumptive clinical…”
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Lateral manus translation for limb‐sparing surgery in 18 dogs with distal radial osteosarcoma in dogs by Séguin, Bernard, Walsh, Peter J., Ehrhart, E. J., Hayden, Eva, Lafferty, Mary H., Selmic, Laura E.

“…Objective To describe and report outcomes after lateral translation of the manus for limb‐sparing management of distal radial osteosarcoma in dogs. Study…”
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The use of novel lymphatic endothelial cell-specific immunohistochemical markers to differentiate cutaneous angiosarcomas in dogs by Halsey, C. H. C., Worley, D. R., Curran, K., Charles, J. B., Ehrhart, E. J.

“…Lymphangiosarcomas are uncommon vascular neoplasms that arise from lymphatic endothelial cells (LECs). They efface and replace normal subcutaneous tissue and…”
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Survivin inhibition via EZN‐3042 in canine lymphoma and osteosarcoma by Shoeneman, J. K., Ehrhart III, E. J., Charles, J. B., Thamm, D. H.

“…Canine lymphoma (LSA) and osteosarcoma (OS) have high mortality rates and remain in need of more effective therapeutic approaches. Survivin, an inhibitor of…”
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Is this cell hollow? by Moore, A Russell, Libby, Arlene L., Khanal, Sujita, Ehrhart III, E. J., Avery, Paul

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HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors by Dailey, Deanna D, Anfinsen, Kristin P, Pfaff, Liza E, Ehrhart, E J, Charles, J Brad, Bønsdorff, Tina B, Thamm, Douglas H, Powers, Barbara E, Jonasdottir, Thora J, Duval, Dawn L

“…Hairy and enhancer of split 1 (HES1), a basic helix-loop-helix transcriptional repressor, is a downstream target of Notch signaling. Notch signaling and HES1…”
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