Search Results - "Ehret, Ralf"
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Cell culture monitoring for drug screening and cancer research: a transparent, microfluidic, multi-sensor microsystem
Published in Lab on a chip (01-01-2014)“…We present a novel, multiparametric microphysiometry system for the dynamic online monitoring of human cancer cell metabolism. The optically transparent,…”
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Online monitoring of cell metabolism for studying pharmacodynamic effects
Published in Toxicology and applied pharmacology (01-04-2007)“…To characterize modes of action of substances and their cytotoxic effects Bionas GmbH has developed a new screening system to allow the continuous recording of…”
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Non-invasive measurement of cell membrane associated proton gradients by ion-sensitive field effect transistor arrays for microphysiological and bioelectronical applications
Published in Biosensors & bioelectronics (01-06-2000)“…The pH in the cellular microenvironment (pH M) is an important regulator of cell-to-cell and cell-to-host interactions. Additionally the extracellular…”
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Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay
Published in Anti-cancer drugs (01-01-2001)“…Although not widely practiced by oncologists, in vitro tumor chemosensitivity assays (TCA) have proved to increase the lifetime of tumor patients in…”
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Evaluation of Bioelectromethanogenesis Part II: Environmental Impact
Published in Chemie ingenieur technik (01-08-2020)“…As already mentioned in part I bioelectromethanogenesis is a power to gas technology that is used to convert electrical power to chemical energy carriers. In…”
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The Bionas® system bridges the gap between in vivo and in vitro
Published in Nature methods (01-08-2007)Get full text
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Simultaneous measurement of cellular respiration and acidification with a single CMOS ISFET
Published in Biosensors & bioelectronics (01-05-2001)“…In vivo, the pH value and oxygen partial pressure are the most important physico–chemical parameters in the microenvironment of human tissues. In vitro, the…”
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Monitoring of cellular signalling and metabolism with modular sensor-technique: The PhysioControl-Microsystem (PCM ®)
Published in Biosensors & bioelectronics (15-03-1998)“…Microsensors provide instruments particularly suited for the noninvasive analysis of cell and tissue cultures. The outstanding benefit lies in the passive…”
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A novel multiparametric microphysiometry system for dynamic cell culture monitoring
Published in 2010 IEEE Sensors (01-11-2010)“…A novel microphysiometry platform for dynamic cell culture monitoring in drug screening and cancer cell research is presented. The transparent system features…”
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Conference Proceeding -
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In vitro system for the prediction of hepatotoxic effects in primary hepatocytes
Published in ALTEX, alternatives to animal experimentation (2007)“…Prediction of liver toxicity and compound responses continues to be a major challenge for the pharmaceutical industry. In vitro studies on liver cells have…”
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Monitoring of cellular signalling and metabolism with modular sensor-technique
Published in Biosensors & bioelectronics (01-03-1998)Get full text
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A case study of API redesign for improved usability
Published in 2008 IEEE Symposium on Visual Languages and Human-Centric Computing (01-09-2008)“…As software grows more complex, software developers' productivity is increasingly defined by their ability to effectively reuse code. Even APIs (application…”
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Conference Proceeding -
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Microsensor-aided measurements of cellular signalling and metabolism on tumor cells. The cell monitoring system (cms(R))
Published in Tumor biology (1998)“…Microsensors provide instruments particularly suited for the rapid, noninvasive and on-line analysis of cell and tissue cultures. The microsensor system…”
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Biofunctional hybrid structures—cell–silicon hybrids for applications in biomedicine and bioinformatics
Published in BIOELECTROCHEM BIOENERG (01-10-1998)“…Cell–silicon hybrids represent miniaturized analytical systems which are qualified by means of the cellular signal processing network to identify biomolecules…”
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Continuous Preparative SEC for Purification of "Difficult-to-Manufacture" Proteins--A Feasibility Study
Published in Biopharm International (01-11-2020)“…The advent of new antibody formats, such as multispecific antibodies or Fc-fusion proteins, imposes new challenges on downstream processing. Classical Protein…”
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Mikrosensorische Systeme in der zellbiologischen Grundlagenforschung und der medizinischen Diagnostik
Published in Die Naturwissenschaften (01-05-1996)Get full text
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