Search Results - "Ehresman, D J"

The atrophy and changes in the cellular compositions of the thymus and spleen observed in mice subjected to short-term exposure to perfluorooctanesulfonate are high-dose phenomena mediated in part by peroxisome proliferator-activated receptor-alpha (PPARα) by Qazi, Mousumi Rahman, Xia, Zhenlei, Bogdanska, Jasna, Chang, Shu-Ching, Ehresman, Dave J, Butenhoff, John L, Nelson, B. Dean, DePierre, Joseph W, Abedi-Valugerdi, Manuchehr

“…Abstract We have previously shown that short-term, high-dose exposure of mice to the environmentally persistent perfluorooctanoate (PFOA) results in thymic and…”
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Phenytoin protein binding and dosage requirements during acute and convalescent phases following brain injury by Markowsky, S J, Skaar, D J, Christie, J M, Eyer, S D, Ehresman, D J

“…To longitudinally evaluate unbound and total serum phenytoin concentrations during intravenous phenytoin maintenance dosage and to determine the relationship…”
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Relative bioavailability of rectally administered phenobarbital sodium parenteral solution by Graves, N M, Holmes, G B, Kriel, R L, Jones-Saete, C, Ong, B, Ehresman, D J

“…Rectal administration of antiepileptic drugs may be a useful alternative route when oral administration is not possible due to illness, surgery, or status…”
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Half-Life of Serum Elimination of Perfluorooctanesulfonate, Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers by Olsen, Geary W., Burris, Jean M., David J. Ehresman, John W. Froehlich, Andrew M. Seacat, Butenhoff, John L., Zobel, Larry R.

“…Background: The presence of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS), and perfluorooctanoate (PFOA) has been reported in humans and…”
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A comparison of the pharmacokinetics of perfluorobutanesulfonate (PFBS) in rats, monkeys, and humans by Olsen, Geary W, Chang, Shu-Ching, Noker, Patricia E, Gorman, Gregory S, Ehresman, David J, Lieder, Paul H, Butenhoff, John L

“…Abstract Materials derived from perfluorobutanesulfonyl fluoride (PBSF, C4 F9 SO2 F) have been introduced as replacements for eight-carbon homolog products…”
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Comparison of human whole blood, plasma, and serum matrices for the determination of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and other fluorochemicals by Ehresman, David J., Froehlich, John W., Olsen, Geary W., Chang, Shu-Ching, Butenhoff, John L.

“…Interest in human exposure to perfluorinated acids, including perfluorobutanesulfonate (PFBS), perfluorohexanesulfonate (PFHS), perfluorooctanesulfonate…”
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Evaluation of potential reproductive and developmental toxicity of potassium perfluorohexanesulfonate in Sprague Dawley rats by Butenhoff, John L., Chang, Shu-Ching, Ehresman, David J., York, Raymond G.

“…This study evaluates the potential reproductive and developmental toxicity of perfluorohexanesulfonate (PFHxS), a surfactant found in sera of the general…”
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Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS) by Chang, Shu-Ching, Thibodeaux, Julie R, Eastvold, Mary L, Ehresman, David J, Bjork, James A, Froehlich, John W, Lau, Christopher, Singh, Ravinder J, Wallace, Kendall B, Butenhoff, John L

“…Abstract Introduction Perfluorooctanesulfonate (PFOS) is widely distributed and persistent in humans and wildlife. Prior toxicological studies have reported…”
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Preliminary evidence of a decline in perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations in American Red Cross blood donors by Olsen, Geary W., Mair, David C., Reagen, William K., Ellefson, Mark E., Ehresman, David J., Butenhoff, John L., Zobel, Larry R.

“…The purpose of this pilot study was to determine whether perfluorooctanesulfonate ( PFOS, C 8 F 17 SO 3 - ) and perfluorooctanoate ( PFOA, C 7 F 15 CO 2 - )…”
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Screening biological samples for underivatized drugs using a splitless injection technique on fused silica capillary column gas chromatography by Ehresman, D J, Price, S M, Lakatua, D J

“…A rapid screening technique is presented for the detection of underivatized drugs using a multi-level temperature program. This allowed for the identification…”
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Longitudinal Assessment of Lipid and Hepatic Clinical Parameters in Workers Involved With the Demolition of Perfluoroalkyl Manufacturing Facilities by Olsen, Geary W., Ehresman, David J., Buehrer, Betsy D., Gibson, Barbara A., Butenhoff, John L., Zobel, Larry R.

“…Objective: To examine in a longitudinal occupational assessment whether changes in serum concentrations of perfluorooctanoic acid (PFOA) and…”
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Circadian and seasonal variation in iodine excretion in children in an endemic goiter area by Sackett-Lundeen, L, Nicolau, G Y, Lakatua, D J, Ehresman, D J, Dumitriu, L, Plinga, L, Petrescu, E, Haus, E

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Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS) by Chang, Shu-Ching, Thibodeaux, Julie R, Eastvold, Mary L, Ehresman, David J, Bjork, James A, Froehlich, John W, Lau, Christopher S, Singh, Ravinder J, Wallace, Kendall B, Butenhoff, John L

“…Abstract Decreases in serum total thyroxine (TT4) and free thyroxine (FT4) without a compensatory rise in thyroid stimulating hormone (thyrotropin or TSH) or…”
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Gestational and lactational exposure to potassium perfluorooctanesulfonate (K super(+)PFOS) in rats: Developmental neurotoxicity by Butenhoff, J L, Ehresman, D J, Chang, S C, Parker, G A, Stump, D G

“…Perfluorooctanesulfonate (PFOS), a persistent and bioaccumulative compound, is widely distributed in humans and wildlife. Exposure of the human fetus and…”
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An interlaboratory study of perfluorinated alkyl compound levels in human plasma by Longnecker, Matthew P., Smith, Cynthia S., Kissling, Grace E., Hoppin, Jane A., Butenhoff, John L., Decker, Emily, Ehresman, David J., Ellefson, Mark E., Flaherty, John, Gardner, Michael S., Langlois, Eric, LeBlanc, Alain, Lindstrom, Andrew B., Reagen, William K., Strynar, Mark J., Studabaker, William B.

“…We conducted an interlaboratory study which differed from the typical study of this type because of its emphasis on comparing intralaboratory variability in…”
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Gestational and lactational exposure to potassium perfluorooctanesulfonate (K super(+)PFOS) in rats: Toxicokinetics, thyroid hormone status, and related gene expression by Chang, S C, Ehresman, D J, Bjork, JA, Wallace, K B, Parker, G A, Stump, D G, Butenhoff, J L

“…Perfluorooctanesulfonate (PFOS), a persistent and accumulative compound, is widely distributed in humans and wildlife. Human exposure can occur early in…”
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