Search Results - "Ehrenkaufer, Richard"

PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys by Nader, Michael A, Morgan, Drake, Gage, H Donald, Nader, Susan H, Calhoun, Tonya L, Buchheimer, Nancy, Ehrenkaufer, Richard, Mach, Robert H

“…Dopamine neurotransmission is associated with high susceptibility to cocaine abuse. Positron emission tomography was used in 12 rhesus macaques to determine if…”
Get full text

Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration by Morgan, Drake, Grant, Kathleen A, Gage, H Donald, Mach, Robert H, Kaplan, Jay R, Prioleau, Osric, Nader, Susan H, Buchheimer, Nancy, Ehrenkaufer, Richard L, Nader, Michael A

“…Disruption of the dopaminergic system has been implicated in the etiology of many pathological conditions, including drug addiction. Here we used positron…”
Get full text

N-[18F]4′-fluorobenzylpiperidin-4yl-(2-fluorophenyl) acetamide ([18F]FBFPA): A potential fluorine-18 labeled PET radiotracer for imaging sigma-1 receptors in the CNS by Mach, Robert H., Gage, H. Donald, Buchheimer, Nancy, Huang, Yunsheng, Kuhner, Ross, Wu, Li, Morton, Thomas E., Ehrenkaufer, Richard L.

“…A series of brain uptake studies and PET imaging studies were conducted with the σ1 selective imaging agent, [18F]FBFPA. The results of the study indicate that…”
Get full text

Morphine-induced spinal cholinergic activation: in vivo imaging with positron emission tomography by Gage, H.Donald, Gage, Jennifer C, Tobin, Joseph R, Chiari, Astrid, Tong, Chuanyao, Xu, Ze-Min, Mach, Robert H, Efange, Simon M.N, Ehrenkaufer, Richard L.E, Eisenach, James C

“…Positron emission tomography (PET) imaging of spinal cord in monkeys with a cholinergic tracer demonstrates increased spinal cholinergic activity in response…”
Get full text

Reproducibility of Repeated Measures of Cholinergic Terminal Density Using [18F](+)-4-Fluorobenzyltrozamicol and PET in the Rhesus Monkey Brain by Gage, H. Donald, Voytko, Mary Lou, Ehrenkaufer, Richard L.E, Tobin, Joseph R, Efange, Simon M.N, Mach, Robert H

Get full text

PET Imaging of Dopamine D2 Receptors with [18F]Fluoroclebopride in Monkeys: Effects of Isoflurane- and Ketamine-Induced Anesthesia by Nader, Michael A, Grant, Kathleen A, Gage, H.Donald, Ehrenkaufer, Richard L, Kaplan, Jay R, Mach, Robert H

“…The purpose of the present study was to determine whether positron emission tomography (PET) studies in monkeys with the dopamine (DA) D2 receptor ligand…”
Get full text

Use of Positron Emission Tomography to Study the Dynamics of Psychostimulant-Induced Dopamine Release by Mach, Robert H, Nader, Michael A, Ehrenkaufer, Richard L.E, Line, Scott W, Smith, Cynthia R, Gage, H.Donald, Morton, Thomas E

“…Microdialysis studies have shown that psychostimulants act through a common neurochemical mechanism of elevating synaptic dopamine content in the…”
Get full text

Social dominance in monkeys: dopamine D 2 receptors and cocaine self-administration by Nader, Michael A, Morgan, Drake, Grant, Kathleen A, Gage, H. Donald, Mach, Robert H, Kaplan, Jay R, Prioleau, Osric, Nader, Susan H, Buchheimer, Nancy, Ehrenkaufer, Richard L

Get full text

Cholinergic activity of aged rhesus monkeys revealed by positron emission tomography by Voytko, Mary Lou, Mach, Robert H., Gage, H. Donald, Ehrenkaufer, Richard L.E., Efange, Simon M.N., Tobin, Joseph R.

“…In the present study, the radiotracer [18F] (+)‐4‐fluorobenzyltrozamicol ((+)‐[18F]FBT) and positron emission tomography (PET) were used to examine the…”
Get full text

Prolonged dopamine and serotonin transporter inhibition after exposure to tropanes by Bennett, Barbara A, Hollingsworth, Charlotte K, Martin, R.Shayn, Childers, Steven R, Ehrenkaufer, Richard E, Porrino, Linda J, Davies, Huw M.L

“…Cocaine and tropane analogs are known to interact with biogenic monoamine transporters by inhibiting amine uptake. Previous in vivo studies have demonstrated…”
Get full text

In vivo imaging of the spinal cord cholinergic system with PET by GAGE, H. D, GAGE, J. C, CHIARI, A, XU, Z.-M, MACH, R. H, EFANGE, S. M. N, EHRENKAUFER, R. L. E, EISENACH, J. C

“…Our goal was to demonstrate the feasibility of an in vivo noninvasive method for imaging spinal cord cholinergic terminals using…”
Get full text

PET imaging studies of dopamine D2 receptors: comparison of [18F]N-methylspiperone and the benzamide analogues [18F]MABN and [18F]MBP in baboon brain by Mach, R H, Ehrenkaufer, R L, Greenberg, J H, Shao, L, Morton, T E, Evora, P H, Nowak, P A, Luedtke, R R, Cohen, D, Reivich, M

“…A series of positron emission tomography (PET) imaging studies was conducted in a baboon with the benzamide derivatives…”
Get more information

Imaging of cholinergic terminals using the radiotracer [18F](+)-4-fluorobenzyltrozamicol: In vitro binding studies and positron emission tomography studies in nonhuman primates by Mach, Robert H., Voytko, Mary Lou, Ehrenkaufer, Richard L.E., Nader, Michael A., Tobin, Joseph R., Efange, Simon M.N., Parsons, Stanley M., Gage, H. Donald, Smith, Cynthia R., Morton, Thomas E.

“…The goal of the present set of studies was to characterize the in vitro binding properties and in vivo tissue kinetics for the vesicular acetylcholine…”
Get full text

Effect of N-alkylation on the affinities of analogs of spiperone for dopamine D2 and serotonin 5-HT2 receptors by Mach, Robert H, Jackson, Joseph R, Luedtke, Robert R, Ivins, Kathryn J, Molinoff, Perry B, Ehrenkaufer, Richard L

“…Two series of N-substituted spiperone analogues were prepared and evaluated in vitro to measure their affinities for dopamine D2 and serotonin 5-HT2 receptors…”
Get full text

Facile, temperature-dependent formation of gaseous C1 and C2 perfluoroalkyl hypofluorites. Applications as electrophilic fluorinating agents by Mulholland, G. Keith, Ehrenkaufer, Richard E

Get full text

Effect of social status on striatal dopamine D2 receptor binding characteristics in cynomolgus monkeys assessed with positron emission tomography by Grant, Kathleen A., Shively, Carol A., Nader, Michael A., Ehrenkaufer, Richard L., Line, Scott W., Morton, Thomas E., Gage, H. Donald, Mach, Robert H.

Get full text

Stereochemical consequences of hydrogen exchange as a result of tritium atom reactions on solid aliphatic amino acids by Ehrenkaufer, Richard Lee E, Hembree, Wylie C, Lieberman, Seymour, Wolf, Alfred P

Get full text

Reproduciblity of repeated measures of cholinergic terminal density using [(18)F]-4-fluorovenzyltrozamicol and PET in the rhesus monkey brain by Gage, H Donald, Voytko, Mary Lou, Ehrenkaufer, Richard L E, Tobin, Joseph R

“…[18F](+)-4-fluorobenzyltrozamicol (FBT), which selectively binds to the vesicular acetylcholine transporter in the presynaptic cholinergic neuron, has…”
Get full text

Social Stress, Depression, and Brain Dopamine in Female Cynomolgus Monkeys by SHIVELY, CAROL A., GRANT, KATHLEEN A., EHRENKAUFER, RICHARD L., MACH, ROBERT H., NADER, MICHAEL A.

“…Socially subordinate adult female cynomolgus monkeys are hypercortisolemic, the targets of aggression, fearful, vigilant, receive little positive affiliative…”
Get full text

Fluorine-18-labeled tropane analogs for PET imaging studies of the dopamine transporter by Mach, Robert H., Nader, Michael A., Ehrenkaufer, Richard L., Gage, H. Donald, Childers, Steven R., Hodges, L. Mark, Hodges, Melinda M., Davies, Huw M.L.

“…A series of PET imaging studies were conducted with two fluorine‐18‐labeled tropane analoges, [18F](+)‐FTT and [18F](+)‐FCT. Both compounds possessed a high…”
Get full text