Search Results - "Ehren, Jennifer"

Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes by Maher, Pamela, Dargusch, Richard, Ehren, Jennifer L, Okada, Shinichi, Sharma, Kumar, Schubert, David

“…The elevated glycation of macromolecules by the reactive dicarbonyl and α-oxoaldehyde methylglyoxal (MG) has been associated with diabetes and its…”
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Concurrent regulation of the transcription factors Nrf2 and ATF4 mediates the enhancement of glutathione levels by the flavonoid fisetin by Ehren, Jennifer L., Maher, Pamela

“…Glutathione (GSH) and GSH-associated metabolism provide the major line of defense for the protection of cells from various forms of toxic stress. GSH also…”
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Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice by Currais, Antonio, Prior, Marguerite, Dargusch, Richard, Armando, Aaron, Ehren, Jennifer, Schubert, David, Quehenberger, Oswald, Maher, Pamela

“…Summary Alzheimer's disease (AD) is the most common type of dementia. It is the only one of the top ten causes of death in the USA for which prevention…”
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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice by Prior, Marguerite, Dargusch, Richard, Ehren, Jennifer L, Chiruta, Chandramouli, Schubert, David

“…Despite years of research, there are no disease-modifying drugs for Alzheimer's disease (AD), a fatal, age-related neurodegenerative disorder. Screening for…”
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Cell and brain tissue imaging of the flavonoid fisetin using label-free two-photon microscopy by Krasieva, Tatiana B., Ehren, Jennifer, O'Sullivan, Thomas, Tromberg, Bruce J., Maher, Pamela

“…Over the last few years, we have identified an orally active, novel neuroprotective and cognition–enhancing molecule, the flavonoid fisetin. Fisetin not only…”
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Food-Grade Enzyme Preparation with Modest Gluten Detoxification Properties by Ehren, Jennifer, Morón, Belen, Martin, Edith, Bethune, Michael T, Gray, Gary M, Khosla, Chaitan

“…Background and Aims: Celiac sprue is a life-long disease characterized by an intestinal inflammatory response to dietary gluten. A gluten-free diet is an…”
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Developing a post-treatment survivorship care plan to help breast cancer survivors understand their fertility by Gorman, Jessica R., Julian, Anne K., Roberts, Samantha A., Romero, Sally A. D., Ehren, Jennifer L., Krychman, Michael L., Boles, Sarah G., Mao, Jun, Irene Su, H.

“…Purpose Reproductive-aged breast cancer survivors (BCS) who have completed initial cancer treatment frequently want to know about their future fertility…”
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Management of sexual dysfunction in breast cancer survivors: a systematic review by Seav, Susan M, Dominick, Sally A, Stepanyuk, Boris, Gorman, Jessica R, Chingos, Diana T, Ehren, Jennifer L, Krychman, Michael L, Su, H Irene

“…Female sexual dysfunction occurs frequently in midlife breast cancer survivors (BCS) and encompasses problems with sexual desire, interest, arousal, orgasm and…”
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Fisetin Blocks Protein Glycation by Two Complimentary Mechanisms; Significance to Diabetes by Ehren, Jennifer, Maher, Pamela

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Coordinated Regulation of the Transcription Factors Nrf2 and ATF4 Mediates the Enhancement of Glutathione Levels by Fisetin by Ehren, Jennifer, Maher, Pam

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Efficacy of a web-based women’s health survivorship care plan for young breast cancer survivors: a randomized controlled trial by Irene Su, H., Stark, Shaylyn, Kwan, Brian, Boles, Sarah, Chingos, Diana, Ehren, Jennifer, Gorman, Jessica R., Krychman, Michael, Romero, Sally A. D., Mao, Jun J., Pierce, John P., Natarajan, Loki

“…Purpose Breast cancer survivorship care plans (SCP) have limited content addressing women’s health issues. This trial tested if young breast cancer survivors…”
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Design of a randomized controlled trial on the efficacy of a reproductive health survivorship care plan in young breast cancer survivors by Stark, Shaylyn S., Natarajan, Loki, Chingos, Diana, Ehren, Jennifer, Gorman, Jessica R., Krychman, Michael, Kwan, Brian, Mao, Jun J., Myers, Emily, Walpole, Tom, Pierce, John P., Su, H. Irene

“…Young breast cancer survivors (YBCS) have unmet needs for managing hot flashes, fertility-related concerns, sexual health, and contraception. Describe the…”
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Fisetin: Flavonoid and Fighter of Diabetic Complications by Ehren, Jennifer, Calcutt, Nigel, Maher, Pamela

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Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in A lzheimer's disease transgenic mice by Currais, Antonio, Prior, Marguerite, Dargusch, Richard, Armando, Aaron, Ehren, Jennifer, Schubert, David, Quehenberger, Oswald, Maher, Pamela

“…Alzheimer's disease ( AD ) is the most common type of dementia. It is the only one of the top ten causes of death in the USA for which prevention strategies…”
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Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: Implications for Celiac Sprue therapy by Gass, Jonathan, Ehren, Jennifer, Strohmeier, Gregg, Isaacs, Indu, Khosla, Chaitan

“…Celiac Sprue is a multi‐factorial disease characterized by an inflammatory response to ingested wheat gluten and similar proteins in rye and barley…”
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Protein engineering of improved prolyl endopeptidases for celiac sprue therapy by Ehren, Jennifer, Govindarajan, Sridhar, Morón, Belén, Minshull, Jeremy, Khosla, Chaitan

“…Due to their unique ability to cleave immunotoxic gluten peptides endoproteolytically, prolyl endopeptidases (PEPs) are attractive oral therapeutic candidates…”
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Identifying and engineering the best oral enzyme therapy for celiac sprue: Two therapeutic options by Ehren, Jennifer

“…Celiac sprue (also known as celiac disease or gluten-sensitive enteropathy) is an inheritable disease characterized by a small intestine inflammatory reaction…”
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Identifying and engineering the best oral enzyme therapy for celiac sprue: Two therapeutic options by Ehren, Jennifer

“…Celiac sprue (also known as celiac disease or gluten-sensitive enteropathy) is an inheritable disease characterized by a small intestine inflammatory reaction…”
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Rational Design of Combination Enzyme Therapy for Celiac Sprue by Siegel, Matthew, Bethune, Michael T., Gass, Jonathan, Ehren, Jennifer, Xia, Jiang, Johannsen, Alexandre, Stuge, Tor B., Gray, Gary M., Lee, Peter P., Khosla, Chaitan

“…Celiac sprue (also known as celiac disease) is an inheritable, gluten-induced enteropathy of the upper small intestine with an estimated prevalence of 0.5%–1%…”
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