Search Results - "Ehlicke, Franziska"
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Osteogenesis and mineralization of mesenchymal stem cells in collagen type I‐based recombinant peptide scaffolds
Published in Journal of biomedical materials research. Part A (01-07-2017)“…Recombinant peptides have the power to harness the inherent biocompatibility of natural macromolecules, while maintaining a defined chemistry for use in tissue…”
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Identifying chondrogenesis strategies for tissue engineering of articular cartilage
Published in Journal of tissue engineering (01-01-2019)“…A key step in the tissue engineering of articular cartilage is the chondrogenic differentiation of mesenchymal stem cells (MSCs) into chondrocytes (native…”
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An Injectable Recombinant Collagen I Peptide-Based Macroporous Microcarrier Allows Superior Expansion of C2C12 and Human Bone Marrow-Derived Mesenchymal Stromal Cells and Supports Deposition of Mineralized Matrix
Published in Tissue engineering. Part A (01-09-2017)“…The development of scaffold formulations based on extracellular matrix (ECM)-inspired synthetic materials constitutes an important resource for the advance of…”
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Ex vivo osteochondral test system with control over cartilage defect depth – A pilot study to investigate the effect of oxygen tension and chondrocyte based treatments in chondral and full thickness defects in an organ model
Published in Osteoarthritis and cartilage open (01-06-2021)“…Cartilage defect treatment strategies are dependent on the lesion size and severity. Osteochondral explant models are a platform to test cartilage repair…”
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Biomimetic in vitro test system for evaluation of dental implant materials
Published in Dental materials (01-08-2020)“…[Display omitted] •Material-dependent biomineralization achieved in vitro.•Performance of gold standard acid-etched titanium confirmed in in vitro test…”
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Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds
Published in Advanced materials (Weinheim) (01-07-2018)“…An integral approach toward in situ tissue engineering through scaffolds that mimic tissue with regard to both tissue architecture and biochemical composition…”
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Ex vivo culture platform for assessment of cartilage repair treatment strategies
Published in ALTEX, alternatives to animal experimentation (2017)“…There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments. In…”
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Inducing chondrogenesis in MSC/chondrocyte co-cultures using exogenous TGF-β: a mathematical model
Published in Journal of theoretical biology (14-02-2018)“…•New model developed for chondrogenic differentiation of mesenchymal stem cells.•Investigated impact of TGF-β and chondrocyte co-culture on MSC…”
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Non-invasive Raman Spectroscopy and Quantitative Real-Time PCR Distinguish Among Undifferentiated Human Mesenchymal Stem Cells and Redifferentiated Nucleus Pulposus Cells and Chondrocytes In Vitro
Published in The open biomedical engineering journal (2017)“…The most common cause of lower back pain is the pathological degeneration of the nucleus pulposus (NP). Promising NP regeneration strategies involving human…”
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Single-Step RNA Extraction from Different Hydrogel-Embedded Mesenchymal Stem Cells for Quantitative Reverse Transcription-Polymerase Chain Reaction Analysis
Published in Tissue engineering. Part C, Methods (01-06-2016)“…For many tissue engineering applications, cells such as human mesenchymal stem cells (hMSCs) must be embedded in hydrogels. The analysis of embedded hMSCs…”
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Intervertebral disc regeneration: influence of growth factors on differentiation of human mesenchymal stem cells (hMSC)
Published in International journal of artificial organs (01-04-2010)“…One common cause of disability in modern society is low back pain. The main reason for this pain is the degeneration of the intervertebral disc (IVD),…”
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Osteogenic differentiation modulated by cross-linking of tissue engineering scaffolds
Published in Frontiers in bioengineering and biotechnology (2016)“…Abstract only…”
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The need for imaging methods in bioengineering of three-dimensional cell cultures
Published in International journal of artificial organs (01-04-2010)“…The analysis of live cells and tissue is gaining increasing importance in research and development. A number of demands are thus being made on the cultivation…”
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