Search Results - "Ehlers, Lisa"

Glucocorticoids-All-Rounders Tackling the Versatile Players of the Immune System by Strehl, Cindy, Ehlers, Lisa, Gaber, Timo, Buttgereit, Frank

“…Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and…”
Get full text

Treat-to-target recommendations in giant cell arteritis and polymyalgia rheumatica by Dejaco, Christian, Kerschbaumer, Andreas, Aletaha, Daniel, Bond, Milena, Hysa, Elvis, Camellino, Dario, Ehlers, Lisa, Abril, Andy, Appenzeller, Simone, Cid, Maria C, Dasgupta, Bhaskar, Duftner, Christina, Grayson, Peter C, Hellmich, Bernhard, Hočevar, Alojzija, Kermani, Tanaz A, Matteson, Eric L, Mollan, Susan P, Neill, Lorna, Ponte, Cristina, Salvarani, Carlo, Sattui, Sebastian Eduardo, Schmidt, Wolfgang A, Seo, Philip, Smolen, Josef S, Thiel, Jens, Toro-Gutiérrez, Carlos Enrique, Whitlock, Madeline, Buttgereit, Frank

“…To develop treat-to-target (T2T) recommendations in giant cell arteritis (GCA) and polymyalgia rheumatica (PMR). A systematic literature review was conducted…”
Get more information

The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding by Ehlers, Lisa, Kirchner, Marieluise, Mertins, Philipp, Strehl, Cindy, Buttgereit, Frank, Gaber, Timo

“…Unspecific antibody binding takes a significant toll on researchers in the form of both the economic burden and the disappointed hopes of promising new…”
Get full text

Age-related increase of mitochondrial content in human memory CD4+ T cells contributes to ROS-mediated increased expression of proinflammatory cytokines by Chen, Yuling, Ye, Yuanchun, Krauß, Pierre-Louis, Löwe, Pelle, Pfeiffenberger, Moritz, Damerau, Alexandra, Ehlers, Lisa, Buttgereit, Thomas, Hoff, Paula, Buttgereit, Frank, Gaber, Timo

“…Cellular metabolism modulates effector functions in human CD4 + T (Th) cells by providing energy and building blocks. Conversely, cellular metabolic responses…”
Get full text

Treat-to-target strategies for the management of familial Mediterranean Fever in children by Ehlers, Lisa, Rolfes, Elisabeth, Lieber, Mareike, Müller, Dominik, Lainka, Elke, Gohar, Faekah, Klaus, Günter, Girschick, Hermann, Hörstermann, Jana, Kümmerle-Deschner, Jasmin, Brunner, Jürgen, Palm-Beden, Katharina, Tenbrock, Klaus, von Wrangel, Lusine, Fasshauer, Maria, Blank, Norbert, Trauzeddel, Ralf, von Stuckrad, Anne Sae Lim, Higgins, Sonja, Welzel, Tatjana, Lutz, Thomas, Hentgen, Véronique, Foell, Dirk, Wittkowski, Helmut, Kallinich, Tilmann

“…Background The objective of this initiative was to develop a treat-to-target (T2T) approach for the management of patients with Familial Mediterranean Fever…”
Get full text

Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism by Ehlers, Lisa, Kuppe, Aditi, Damerau, Alexandra, Wilantri, Siska, Kirchner, Marieluise, Mertins, Philipp, Strehl, Cindy, Buttgereit, Frank, Gaber, Timo

Get full text

What a difference ADA2 makes: Insights into the pathophysiology of ADA2 deficiency from single‐cell RNA sequencing of monocytes by Ehlers, Lisa, Meyts, Isabelle

“…Graphical Discussion on the increase in nonclassical monocytes in patients with DADA2 as shown by scRNA seq; these pro inflammatory cells also show increased…”
Get full text

Evidence on treat to target strategies in polymyalgia rheumatica and giant cell arteritis: a systematic literature review by Hysa, Elvis, Bond, Milena, Ehlers, Lisa, Camellino, Dario, Falzon, Louise, Dejaco, Christian, Buttgereit, Frank, Aletaha, Daniel, Kerschbaumer, Andreas

“…To inform an international task force about current evidence on Treat to Target (T2T) strategies in PMR and GCA. A systematic literature research (SLR) was…”
Get full text

Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism by Ehlers, Lisa, Kuppe, Aditi, Damerau, Alexandra, Wilantri, Siska, Kirchner, Marieluise, Mertins, Philipp, Strehl, Cindy, Buttgereit, Frank, Gaber, Timo

“…Adenine nucleotides represent crucial immunomodulators in the extracellular environment. The ectonucleotidases CD39 and CD73 are responsible for the sequential…”
Get full text

ADA2 Deficiency Mimicking Acute Disseminated Encephalomyelitis by Ehlers, Lisa, Bucciol, Giorgia, Beysen, Diane, Meyts, Isabelle

Get full text

Human ADA2 Deficiency: Ten Years Later by Wouters, Marjon, Ehlers, Lisa, Dzhus, Mariia, Kienapfel, Verena, Bucciol, Giorgia, Delafontaine, Selket, Hombrouck, Anneleen, Pillay, Bethany, Moens, Leen, Meyts, Isabelle

“…Purpose of Review In this review, an update is provided on the current knowledge and pending questions about human adenosine deaminase type 2 deficiency…”
Get full text

A Narrative Review of the Neurological Manifestations of Human Adenosine Deaminase 2 Deficiency by Dzhus, Mariia, Ehlers, Lisa, Wouters, Marjon, Jansen, Katrien, Schrijvers, Rik, De Somer, Lien, Vanderschueren, Steven, Baggio, Marco, Moens, Leen, Verhaaren, Benjamin, Lories, Rik, Bucciol, Giorgia, Meyts, Isabelle

“…Deficiency of human adenosine deaminase type 2 (DADA2) is a complex systemic autoinflammatory disorder characterized by vasculopathy, immune dysregulation, and…”
Get full text

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases by Damerau, Alexandra, Kirchner, Marieluise, Pfeiffenberger, Moritz, Ehlers, Lisa, Do Nguyen, Duc Ha, Mertins, Philipp, Bartek, Benjamin, Maleitzke, Tazio, Palmowski, Yannick, Hardt, Sebastian, Winkler, Tobias, Buttgereit, Frank, Gaber, Timo

“…Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of age-related disability worldwide, mainly due to pain, the disease's main…”
Get full text

Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome by Delafontaine, Selket, Lannuzzo, Alberto, Bigley, Tarin M, Mylemans, Bram, Rana, Ruchit, Baatsen, Pieter, Poli, Maria Cecilia, Rymen, Daisy, Jansen, Katrien, Mekahli, Djalila, Casteels, Ingele, Cassiman, Catherine, Demaerel, Philippe, Lepelley, Alice, Frémond, Marie-Louise, Schrijvers, Rik, Bossuyt, Xavier, Vints, Katlijn, Huybrechts, Wim, Tacine, Rachida, Willekens, Karen, Corveleyn, Anniek, Boeckx, Bram, Baggio, Marco, Ehlers, Lisa, Munck, Sebastian, Lambrechts, Diether, Voet, Arnout, Moens, Leen, Bucciol, Giorgia, Cooper, Megan A, Davis, Carla M, Delon, Jérôme, Meyts, Isabelle

“…Mutations in the N-terminal WD40 domain of coatomer protein complex subunit a (CORA) cause a type I interferonopathy, typically characterized by alveolar…”
Get full text

Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome by Delafontaine, Selket, Iannuzzo, Alberto, Bigley, Tarin M, Mylemans, Bram, Rana, Ruchit, Baatsen, Pieter, Poli, Maria Cecilia, Rymen, Daisy, Jansen, Katrien, Mekahli, Djalila, Casteels, Ingele, Cassiman, Catherine, Demaerel, Philippe, Lepelley, Alice, Frémond, Marie-Louise, Schrijvers, Rik, Bossuyt, Xavier, Vints, Katlijn, Huybrechts, Wim, Tacine, Rachida, Willekens, Karen, Corveleyn, Anniek, Boeckx, Bram, Baggio, Marco, Ehlers, Lisa, Munck, Sebastian, Lambrechts, Diether, Voet, Arnout, Moens, Leen, Bucciol, Giorgia, Cooper, Megan A, Davis, Carla M, Delon, Jérôme, Meyts, Isabelle

“…Mutations in the N-terminal WD40 domain of coatomer protein complex subunit α (COPA) cause a type I interferonopathy, typically characterized by alveolar…”
Get full text

Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome by Riestra, Maria Rodrigo, Pillay, Bethany A., Willemsen, Mathijs, Kienapfel, Verena, Ehlers, Lisa, Delafontaine, Selket, Pinton, Antoine, Wouters, Marjon, Hombrouck, Anneleen, Sauer, Kate, Bossuyt, Xavier, Voet, Arnout, Soenen, Stefaan J., Conde, Cecilia Dominguez, Bucciol, Giorgia, Boztug, Kaan, Humblet-Baron, Stephanie, Touzart, Aurore, Rieux-Laucat, Frédéric, Notarangelo, Luigi D., Moens, Leen, Meyts, Isabelle

“…The DNA polymerase δ complex (PolD), comprising catalytic subunit POLD1 and accessory subunits POLD2, POLD3, and POLD4, is essential for DNA synthesis and is…”
Get full text

2018 EULAR recommendations for a core data set to support observational research and clinical care in giant cell arteritis by Ehlers, Lisa, Askling, Johan, Bijlsma, Hans Wj, Cid, Maria Cinta, Cutolo, Maurizio, Dasgupta, Bhaskar, Dejaco, Christian, Dixon, William G, Feltelius, Nils, Finckh, Axel, Gilbert, Kate, Mackie, Sarah Louise, Mahr, Alfred, Matteson, Eric L, Neill, Lorna, Salvarani, Carlo, Schmidt, Wolfgang A, Strangfeld, Anja, van Vollenhoven, Ronald F, Buttgereit, Frank

“…Giant cell arteritis (GCA) represents the most common form of primary systemic vasculitis and is frequently associated with comorbidities related to the…”
Get more information

Neolithic settlement sites in Western Turkey — palaeogeographic studies at Çukuriçi Höyük and Arvalya Höyük by Stock, Friederike, Ehlers, Lisa, Horejs, Barbara, Knipping, Maria, Ladstätter, Sabine, Seren, Sirri, Brückner, Helmut

“…Çukuriçi Höyük and Arvalya Höyük are two prehistoric settlement mounds (tells) located in parallel striking valleys in the environs of Ephesus, W Turkey. They…”
Get full text