Search Results - "Ehigie, Adeola"
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Chemical constituents of water hyacinth (Eichhornia crassipes) methanol leaf extract and its effect on selected enzymes of Periplaneta americana
Published in Biotechnologia (Poznan) (2020)“…Eichhornia crassipes (water hyacinth) possesses several biological properties. Periplaneta americana (cockroach) is a household insect pest that can…”
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Potential inhibitory properties of structurally modified quercetin/isohamnetin glucosides against SARS-CoV-2 Mpro; molecular docking and dynamics simulation strategies
Published in Informatics in medicine unlocked (2023)“…Concerned organizations and individuals are fully engaged in seeking appropriate measures towards managing Severe Acute Respiratory Syndrome Coronavirus 2…”
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Effects of Plumbago zeylanica (L.) Root Extracts on Mitochondrial Membrane Permeability Transition Pore (MMPTP) and some Biochemical Parameters in Male Albino Rats
Published in The FASEB journal (01-05-2021)“…Medicinal plants induce apoptosis through the opening of the Mitochondrial Membrane Permeability Transition Pore (MMPTP). Pathogenesis of diseases like Cancer,…”
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Targeting the mitochondrial permeability transition pore for drug discovery: Challenges and opportunities
Published in Mitochondrion (01-03-2022)“…•MPTP is involved in the pathogenesis of human disease.•Inhibition of the MPTP has therapeutic implications in neuro-diseases and IR.•Induction of MPTP can…”
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Effects of soil types on phytochemical constituents and antioxidant properties of Solanum nigrum
Published in South African journal of botany (01-12-2022)“…•The influence of soil textural types on phytochemical constituents and antioxidant properties of cultivated S. nigrum was evaluated.•The bioactive compounds…”
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Treatment with Momordica charantia Fractions Disrupts Energy Metabolism and Elevated Reactive Oxygen Species’ Generation in Human Lung and Breast Cancer Cell Lines
Published in The FASEB journal (01-04-2020)“…The mechanism of action of mitochondrial targeted anti‐cancer drugs relies on their ability to disrupt the energy producing systems of cancer cell…”
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Momordica charantia L. induces non-apoptotic cell death in human MDA-MB-436 breast and A549 lung cancer cells by disrupting energy metabolism and exacerbating reactive oxygen species’ generation
Published in Journal of ethnopharmacology (15-09-2021)“…Bitter melon, Momordica charantia L. (MC), is an ethnomedicinal plant cultivated in different climes. It's cytotoxic effect on several cancer cell lines has…”
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Ameliorative role of Syzygium aromaticum aqueous extract on synaptosomal tyrosine hydroxylase activity, oxidative stress parameters, and behavioral changes in lead‐induced neurotoxicity in mice
Published in Journal of food biochemistry (01-07-2022)“…This study reports the protective role of the aqueous extract of Syzygium aromaticum (ESA) against lead (Pb)‐induced neurotoxicity in mice. Thirty male mice…”
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Induction of a Non‐Apoptotic Cell Death in Momordica Charantia ‐Treated Human Cancer Cell Lines
Published in The FASEB journal (01-04-2019)“…One major mechanism of death in cancer cells is via the induction of apoptosis, the best‐studied form of programmed cell death. Although apoptosis is essential…”
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Evaluation of the Antioxidant Potential of Aqueous Extracts of Moringa oleifera Leaf and Cocos nucifera Husk: A Comparative Analysis
Published in Pharmaceutical and biomedical research (07-05-2022)“…Background: Oxidative Stress (OS) can result in several diseases, such as cancer or neurodegenerative illnesses. Plant antioxidants can supplement the body’s…”
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Jatonik polyherbal mixture induced rat liver MMPT pore opening in normal Wistar rat: In vitro and in vivo studies
Published in Chinese herbal medicines (01-01-2024)“…To assess acute toxicity, the in vitro and in vivo effects of methanol and ethyl acetate extracts (JME and JEE) of Jatonik polyherbal mixture on some…”
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Evaluation of the Antioxidant Potential of Aqueous Extracts of Moringa oleifera Leaf and Cocos nucifera Husk: A Comparative Analysis
Published in Pharmaceutical and biomedical research (01-09-2021)“…Background: Oxidative Stress (OS) can result in several diseases, such as cancer or neurodegenerative illnesses. Plant antioxidants can supplement the body’s…”
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