Search Results - "Ehemann, V."

MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival by Afanasyeva, E A, Mestdagh, P, Kumps, C, Vandesompele, J, Ehemann, V, Theissen, J, Fischer, M, Zapatka, M, Brors, B, Savelyeva, L, Sagulenko, V, Speleman, F, Schwab, M, Westermann, F

“…Several microRNA (miRNA) loci are found within genomic regions frequently deleted in primary neuroblastoma, including miR-885-5p at 3p25.3. In this study, we…”
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Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma by Kocak, H, Ackermann, S, Hero, B, Kahlert, Y, Oberthuer, A, Juraeva, D, Roels, F, Theissen, J, Westermann, F, Deubzer, H, Ehemann, V, Brors, B, Odenthal, M, Berthold, F, Fischer, M

“…Neuroblastoma is an embryonal malignancy of the sympathetic nervous system. Spontaneous regression and differentiation of neuroblastoma is observed in a subset…”
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The PEA-15 PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK MAP kinase pathway by Eckert, A, Böck, B C, Tagscherer, K E, Haas, T L, Grund, K, Sykora, J, Herold-Mende, C, Ehemann, V, Hollstein, M, Chneiweiss, H, Wiestler, O D, Walczak, H, Roth, W

“…PEA-15 (phosphoprotein enriched in astrocytes 15 kDa) is a death effector domain-containing protein, which is involved in the regulation of apoptotic cell…”
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Radiosensitization by histone deacetylase inhibition in an osteosarcoma mouse model by Blattmann, C., Thiemann, M., Stenzinger, A., Christmann, A., Roth, E., Ehemann, V., Debus, J., Kulozik, A.E., Weichert, W., Huber, P.E., Oertel, S., Abdollahi, A.

“…Background Osteosarcomas (OS) are highly malignant and radioresistant tumors. Histone deacetylase inhibitors (HDACi) constitute a novel class of anticancer…”
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TRAIL-mediated apoptosis in malignant glioma cells is augmented by celecoxib through proteasomal degradation of survivin by Gaiser, T., Becker, M.R., Habel, A., Reuss, D.E., Ehemann, V., Rami, A., Siegelin, M.D.

“…Celecoxib is a cyclooxygenase 2-selective nonsteroidal anti-inflammatory drug (NSAID) that exhibited therapeutic activity in cancer. In this study three…”
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Suberoylanilide hydroxamic acid affects γH2AX expression in osteosarcoma, atypical teratoid rhabdoid tumor and normal tissue cell lines after irradiation by Blattmann, C., Oertel, S., Thiemann, M., Weber, K.J., Schmezer, P., Zelezny, O., Lopez Perez, R., Kulozik, A.E., Debus, J., Ehemann, V.

“…Purpose Osteosarcoma and atypical teratoid rhabdoid tumors are tumor entities with varying response to common standard therapy protocols. Histone acetylation…”
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Correlation of Smac/DIABLO protein expression with the clinico-pathological features of breast cancer patients by Pluta, P, Cebula-Obrzut, B, Ehemann, V, Pluta, A, Wierzbowska, A, Piekarski, J, Bilski, A, Nejc, D, Kordek, R, Robak, T, Smolewski, P, Jeziorski, A

“…Smac/DIABLO protein promotes caspase-dependent apoptosis by inhibition of inhibitor of apoptosis protein (IAP) family members. The role of Smac/DIABLO in…”
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Rheumatoid arthritis and pigmented villonodular synovitis: comparative analysis of cell polyploidy, cell cycle phases and expression of macrophage and fibroblast markers in proliferating synovial cells by Berger, I, Weckauf, H, Helmchen, B, Ehemann, V, Penzel, R, Fink, B, Bernd, L, Autschbach, F

“…Aims : Rheumatoid arthritis (RA) and pigmented villonodular synovitis (PVNS) are aggressive diseases with progressive joint destruction. The present study aims…”
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MYCN/MYC-mediated drug resistance mechanisms in neuroblastoma by Gogolin, S, Dreidax, D, Becker, G, Ehemann, V, Schwab, M, Westermann, F

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Decreased apoptosis despite severe CD4 depletion in the thymus of a human immunodeficiency virus-1 infected child by Brunner, J, Boehler, T, Ehemann, V, Kassam, S, Otto, H, Sergi, C

“…Thymic epithelial space (TES), where thymopoiesis is located, and thymic perivascular space (PVS), where T lymphocytes are pooled, appear differentially…”
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Aberrant cytoplasmic expression of the p16 protein in breast cancer is associated with accelerated tumour proliferation by EMIG, R, MAGENER, A, EHEMANN, V, MEYER, A, STILGENBAUER, F, VOLKMANN, M, WALLWIENER, D, SINN, H.-P

“…The p16 protein plays an important role in the transition of cells into the G1 phase of the cell cycle. We have studied the prevalence of p16 protein…”
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Expression pattern of cell cycle-related gene products in synovial stroma and synovial lining in active and quiescent stages of rheumatoid arthritis by Helmchen, B, Weckauf, H, Ehemann, V, Wittmann, I, Meyer-Scholten, C, Berger, I

“…To investigate the expression pattern of cell cycle related gene products in active and quiescent Rheumatoid arthritis (RA). Synovial tissue from 20 patients…”
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Apoptosis resistance in pigmented villonodular synovitis by Berger, I, Aulmann, S, Ehemann, V, Helmchen, B, Weckauf, H

“…Pigmented villonodular synovitis (PVNS) is a proliferative lesion originating from synovial tissue with a locally aggressive behaviour. We analysed the…”
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Preferential radiosensitization in p53-mutated human tumour cell lines by pentoxifylline-mediated disruption of the G2/M checkpoint control by Strunz, A. M., Peschke, P., Waldeck, W., Ehemann, V., Kissel, M., Debus, J.

“…Purpose : There is evidence that the duration of the G2/M delay following irradiation is correlated with cell survival. We studied the radiosensitizing…”
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Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations by Weber, R G, Bridger, J M, Benner, A, Weisenberger, D, Ehemann, V, Reifenberger, G, Lichter, P

“…Although alterations in chromosome number have frequently been detected in human tumor cells and associated with tumor initiation and progression, the causal…”
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Strong expression of Bcl-2 in pigmented villonodular synovitis of the knee with aggressive clinical behaviour by Berger, I., Paessler, H. H., Weckauf, H., Ehemann, V., Helmchen, B.

“…Objective: To determine the expression of bcl-2, p53, and caspase 3, and measure the Ki-67 proliferation index as well as DNA content and DNA fragmentation in…”
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Effects of mTOR Inhibition On IR/IGF-1R Signalling in PIK3CA-Mutated, Tamoxifen Resistant Breast Cancer by Mietzsch, F., Sinn, H.P., Ehemann, V., Schirmacher, P., Trumpp, A., Aulmann, S.

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Three-dimensional analysis of cell nucleus structures visualized by confocal scanning laser microscopy by Kett, P, Geiger, B, Ehemann, V, Komitowski, D

“…Studies of the three-dimensional (3-D) organization of cell nuclei are becoming increasingly important for the understanding of basic cellular events such as…”
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Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3 by Kopitz, Jürgen, von Reitzenstein, Carolina, André, Sabine, Kaltner, Herbert, Uhl, Johannes, Ehemann, Volker, Cantz, Michael, Gabius, Hans-Joachim

“…The cell density-dependent growth inhibition of human SK-N-MC neuroblastoma cells is initiated by increased ganglioside sialidase activity leading to elevated…”
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Cellular compartments in mitotic cells: ultrahistochemical identification of Golgi elements in PtK-1 cells by Schroeter, D, Ehemann, V, Paweletz, N

“…This investigation focuses on the identification, distribution, and transport of intracellular membrane systems during mitosis. The membranes of the Golgi…”
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