Search Results - "Ehe, Ben"

Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1 by Ehe, Ben K., Lamson, David R., Tarpley, Michael, Onyenwoke, Rob U., Graves, Lee M., Williams, Kevin P.

“…GLI1 is a key downstream transcription effector of the Hedgehog (Hh) signaling pathway that is involved in promoting cell growth, differentiation and tissue…”
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Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells by Oladapo, Helen O., Tarpley, Michael, Sauer, Scott J., Addo, Kezia A., Ingram, Shalonda M., Strepay, Dillon, Ehe, Ben K., Chdid, Lhoucine, Trinkler, Michael, Roques, Jose R., Darr, David B., Fleming, Jodie M., Devi, Gayathri R., Williams, Kevin P.

“…Activation of the Hedgehog (Hh) pathway effector GLI1 is linked to tumorigenesis and invasiveness in a number of cancers, with targeting of GLI1 by small…”
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Data on peptides identified by mass spectrometry analysis of in vitro DYRK1A-mediated phosphorylation sites on GLI1 by Ehe, Ben K., Lamson, David R., Tarpley, Michael, Onyenwoke, Rob U., Graves, Lee M., Williams, Kevin P.

“…The data presented in this article support the accompanying research article “Identification of a DYRK1A-mediated phosphorylation site within the nuclear…”
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Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays by Lamson, David R., Tarpley, Michael, Addo, Kezia, Ji, Xiaojia, Abu Rabe, Dina, Ehe, Ben, Hughes, Mark, Smith, Ginger R., Daye, Laura R., Musso, David L., Zheng, Weifan, Williams, Kevin P.

“…Sonic hedgehog (Shh) is a morphogen with important roles in embryonic development and in the development of a number of cancers. Its activity is modulated by…”
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Abstract 680: Identification of GLI1 antagonists for breast cancer therapy by Oladapo, Helen, Fleming, Jodie M., Addo, Kezia, Tarpley, Mike, Ehe, Ben, Ingram, Shalonda, Sauer, Scott, Devi, Gayathri, Williams, Kevin P.

“…Introduction: The transcription factor, glioma-associated oncogene homolog 1 (GLI1) is a downstream marker for hedgehog (Hh) pathway activation. Recently,…”
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