Search Results - "Ehaideb, Salleh N"

Evidence of a wide gap between COVID-19 in humans and animal models: a systematic review by Ehaideb, Salleh N, Abdullah, Mashan L, Abuyassin, Bisher, Bouchama, Abderrezak

“…Animal models of COVID-19 have been rapidly reported after the start of the pandemic. We aimed to assess whether the newly created models reproduce the full…”
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prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies by Ehaideb, Salleh N., Iyengar, Atulya, Ueda, Atsushi, Iacobucci, Gary J., Cranston, Cathryn, Bassuk, Alexander G., Gubb, David, Axelrod, Jeffrey D., Gunawardena, Shermali, Wu, Chun-Fang, Manak, J. Robert

“…Recent analyses in flies, mice, zebrafish, and humans showed that mutations in prickle orthologs result in epileptic phenotypes, although the mechanism…”
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Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase by Paemka, Lily, Mahajan, Vinit B, Ehaideb, Salleh N, Skeie, Jessica M, Tan, Men Chee, Wu, Shu, Cox, Allison J, Sowers, Levi P, Gecz, Jozef, Jolly, Lachlan, Ferguson, Polly J, Darbro, Benjamin, Schneider, Amy, Scheffer, Ingrid E, Carvill, Gemma L, Mefford, Heather C, El-Shanti, Hatem, Wood, Stephen A, Manak, J Robert, Bassuk, Alexander G

“…Epilepsy is a common disabling disease with complex, multifactorial genetic and environmental etiology. The small fraction of epilepsies subject to Mendelian…”
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Enhancing Gentamicin Antibacterial Activity by Co-Encapsulation with Thymoquinone in Liposomal Formulation by Alzahrani, Raghad R, Alkhulaifi, Manal M, Al Jeraisy, Majed, Albekairy, Abdulkareem M, Ali, Rizwan, Alrfaei, Bahauddeen M, Ehaideb, Salleh N, Al-Asmari, Ahmed I, Qahtani, Sultan Al, Halwani, Abdulaziz, Yassin, Alaa Eldeen B, Halwani, Majed A

“…Gentamicin (GEN) is a broad-spectrum antibiotic that cannot be prescribed freely because of its toxicity. Thymoquinone (THQ), a phytochemical, has…”
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Novel homozygous mutation in the WWOX gene causes seizures and global developmental delay: Report and review by Ehaideb, Salleh N., Al-Bu Ali, Majed J., Al-obaid, Jaafer J., Aljassim, Kareemah M., Alfadhel, Majid

“…The gene has a WW domain containing oxidoreductase, which is located at the common fragile site FRA16D at chromosome 16q23. is a tumor suppressor gene that has…”
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Interferon-induced transmembrane protein-3 genetic variant rs12252 is associated with COVID-19 mortality by Alghamdi, Jahad, Alaamery, Manal, Barhoumi, Tlili, Rashid, Mamoon, Alajmi, Hala, Aljasser, Nasser, Alhendi, Yaseen, Alkhalaf, Hind, Alqahtani, Hanadi, Algablan, Omer, Alshaya, Abdulraham I., Tashkandi, Nabiha, Massadeh, Salam, Almuzzaini, Bader, Ehaideb, Salleh N., Bosaeed, Mohammad, Ayoub, Kamal, Yezli, Saber, Khan, Anas, Alaskar, Ahmed, Bouchama, Abderrezak

“…Interferon-induced membrane proteins (IFITM) 3 gene variants are known risk factor for severe viral diseases. We examined whether IFITM3 variant may underlie…”
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KCNT1‐related epilepsy: An international multicenter cohort of 27 pediatric cases by Borlot, Felippe, Abushama, Ahmed, Morrison‐Levy, Nadine, Jain, Puneet, Puthenveettil Vinayan, Kollencheri, Abukhalid, Musaad, Aldhalaan, Hesham M., Almuzaini, Hanin S., Gulati, Sheffali, Hershkovitz, Tova, Konanki, Ramesh, Lingappa, Lokesh, Luat, Aimee F., Shafi, Shatha, Tabarki, Brahim, Thomas, Maya, Yoganathan, Sangeetha, Alfadhel, Majid, Arya, Ravindra, Donner, Elizabeth J., Ehaideb, Salleh N., Gowda, Vykuntaraju K., Jain, Vivek, Madaan, Priyanka, Myers, Kenneth A., Otsubo, Hiroshi, Panda, Prateek, Sahu, Jitendra K., Sampaio, Letícia P. B., Sharma, Suvasini, Simard‐Tremblay, Elisabeth, Zak, Maria, Whitney, Robyn

“…Objective Through international collaboration, we evaluated the phenotypic aspects of a multiethnic cohort of KCNT1‐related epilepsy and explored…”
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Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans by Tao, Hirotaka, Manak, J. Robert, Sowers, Levi, Mei, Xue, Kiyonari, Hiroshi, Abe, Takaya, Dahdaleh, Nader S., Yang, Tian, Wu, Shu, Chen, Shan, Fox, Mark H., Gurnett, Christina, Montine, Thomas, Bird, Thomas, Shaffer, Lisa G., Rosenfeld, Jill A., McConnell, Juliann, Madan-Khetarpal, Suneeta, Berry-Kravis, Elizabeth, Griesbach, Hilary, Saneto, Russell P., Scott, Matthew P., Antic, Dragana, Reed, Jordan, Boland, Riley, Ehaideb, Salleh N., El-Shanti, Hatem, Mahajan, Vinit B., Ferguson, Polly J., Axelrod, Jeffrey D., Lehesjoki, Anna-Elina, Fritzsch, Bernd, Slusarski, Diane C., Wemmie, John, Ueno, Naoto, Bassuk, Alexander G.

“…Epilepsy is heritable, yet few causative gene mutations have been identified, and thus far no human epilepsy gene mutations have been found to produce seizures…”
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PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders by Paemka, Lily, Mahajan, Vinit B, Skeie, Jessica M, Sowers, Levi P, Ehaideb, Salleh N, Gonzalez-Alegre, Pedro, Sasaoka, Toshikuni, Tao, Hirotaka, Miyagi, Asuka, Ueno, Naoto, Takao, Keizo, Miyakawa, Tsuyoshi, Wu, Shu, Darbro, Benjamin W, Ferguson, Polly J, Pieper, Andrew A, Britt, Jeremiah K, Wemmie, John A, Rudd, Danielle S, Wassink, Thomas, El-Shanti, Hatem, Mefford, Heather C, Carvill, Gemma L, Manak, J Robert, Bassuk, Alexander G

“…The frequent comorbidity of Autism Spectrum Disorders (ASDs) with epilepsy suggests a shared underlying genetic susceptibility; several genes, when mutated,…”
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Mutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans by Ehaideb, Salleh N., Wignall, Elizabeth A., Kasuya, Junko, Evans, William H., Iyengar, Atulya, Koerselman, Haley L., Lilienthal, Anthony J., Bassuk, Alexander G., Kitamoto, Toshihiro, Manak, J. Robert

“…Objective Genetically tractable fruit flies have been used for decades to study seizure disorders. However, there is a paucity of data specifically correlating…”
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Seizures are regulated by ubiquitin-specific peptidase 9 X-linked by Paemka, Lily, Mahajan, Vinit B, Ehaideb, Salleh N, Skeie, Jessica M, Tan, Men Chee, Wu, Shu, Cox, Allison J, Sowers, Levi P, Gecz, Jozef, Jolly, Lachlan, Ferguson, Polly J, Darbro, Benjamin, Schneider, Amy, Scheffer, Ingrid E, Carvill, Gemma L, Mefford, Heather C, El-Shanti, Hatem, Wood, Stephen A, Manak, J. Robert, Bassuk, Alexander G

“…Epilepsy is a common disabling disease with complex, multifactorial genetic and environmental etiology. The small fraction of epilepsies subject to Mendelian…”
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Seizures Are Regulated by Ubiquitin-specific Peptidase 9 X-linked (USP9X), a De-Ubiquitinase: e1005022 by Paemka, Lily, Mahajan, Vinit B, Ehaideb, Salleh N, Skeie, Jessica M, Tan, Men Chee, Wu, Shu, Cox, Allison J, Sowers, Levi P, Gecz, Jozef, Jolly, Lachlan, Ferguson, Polly J, Darbro, Benjamin, Schneider, Amy, Scheffer, Ingrid E, Carvill, Gemma L, Mefford, Heather C, El-Shanti, Hatem, Wood, Stephen A, Manak, J Robert, Bassuk, Alexander G

“…Epilepsy is a common disabling disease with complex, multifactorial genetic and environmental etiology. The small fraction of epilepsies subject to Mendelian…”
Get full text