Mastitis: Impact of Dry Period, Pathogens, and Immune Responses on Etiopathogenesis of Disease and its Association with Periparturient Diseases

Mastitis is an inflammation of the mammary gland initiated by pathogenic bacteria. In fact, mastitis is the second most important reason for the culling of cows from dairy herds, after infertility. In this review we focus on various forms of mastitis, including subclinical and clinical mastitis. We...

Full description

Saved in:

Bibliographic Details
Published in:	Dairy (Basel) Vol. 3; no. 4; pp. 881 - 906
Main Authors:	Egyedy, Ashley F., Ametaj, Burim N.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 01-12-2022
Subjects:	Adaptive immunity Bacteria Cattle Dairy cattle dairy cow Dairy farming Dairy farms Dairy industry Disease Endometritis Farms Gram-negative bacteria Gram-positive bacteria Immune response Immunity Infections Infertility Inflammation Mammary gland Mammary glands Mastitis Metritis Milk Milk production Pathogens periparturient diseases Reviews Udder Canada United States > US
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Mastitis is an inflammation of the mammary gland initiated by pathogenic bacteria. In fact, mastitis is the second most important reason for the culling of cows from dairy herds, after infertility. In this review we focus on various forms of mastitis, including subclinical and clinical mastitis. We also stress the importance of the dry-off period as an important time when pathogenic bacteria might start their insult to the mammary gland. An important part of the review is the negative effects of mastitis on milk production and composition, as well as economic consequences for dairy farms. The two most important groups of bacteria that are involved in infection of the udder, Gram-negative and Gram-positive bacteria, are also discussed. Although all cows have both innate and adaptive immunity against most pathogens, some are more susceptible to the disease than others. That is why we summarize the most important components of innate and adaptive immunity so that the reader understands the specific immune responses of the udder to pathogenic bacteria. One of the most important sections of this review is interrelationship of mastitis with other diseases, especially retained placenta, metritis and endometritis, ketosis, and laminitis. Is mastitis the cause or the consequence of this disease? Finally, the review concludes with treatment and preventive approaches to mastitis.
ISSN:	2624-862X 2624-862X
DOI:	10.3390/dairy3040061