Search Results - "Egormin, Peter A."

Metformin slows down aging and extends life span of female SHR mice by Anisimov, Vladimir N., Berstein, Lev M., Egormin, Peter A., Piskunova, Tatiana S., Popovich, Irina G., Zabezhinski, Mark A., Tyndyk, Margarita L., Yurova, Maria V., Kovalenko, Irina G., Poroshina, Tatiana E., Semenchenko, Anna V.

“…Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer. It…”
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If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice by Anisimov, Vladimir N, Berstein, Lev M, Popovich, Irina G, Zabezhinski, Mark A, Egormin, Peter A, Piskunova, Tatiana S, Semenchenko, Anna V, Tyndyk, Margarita L, Yurova, Maria N, Kovalenko, Irina G, Poroshina, Tatiana E

“…Hyperglycemia and hyperinsulinemia accelerate both aging and cancer. Antidiabetic biguanides such as metformin decrease glucose, insulin and IGF-1 level…”
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Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo by Anisimov, Vladimir N., Egormin, Peter A., Piskunova, Tatiana S., Popovich, Irina G., Tyndyk, Margarita L., Yurova, Maria N., Zabezhinski, Mark A., Anikin, Ivan V., Karkach, Arseniy S., Romanyukha, Alexey A.

“…Population studies have shown that treatment with the antidiabetic biguanide metformin significantly reduced cancer risk. In our animal studies, metformin…”
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Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice by Anisimov, Vladimir N., Berstein, Lev M., Egormin, Peter A., Piskunova, Tatiana S., Popovich, Irina G., Zabezhinski, Mark A., Kovalenko, Irina G., Poroshina, Tatiana E., Semenchenko, Anna V., Provinciali, Mauro, Re, Francesca, Franceschi, Claudio

“…Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer…”
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Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin by Anisimov, Vladimir N, Popovich, Irina G, Zabezhinski, Mark A, Egormin, Peter A, Yurova, Maria N, Semenchenko, Anna V, Tyndyk, Margarita L, Panchenko, Andrey V, Trashkov, Alexandr P, Vasiliev, Andrey G, Khaitsev, Nikolai V

“…The perinatal (prenatal and early neonatal) period is a critical stage for hypothalamic programming of sexual differentiation as well as for the development of…”
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Central and Peripheral Effects of Insulin/IGF-1 Signaling in Aging and Cancer: Antidiabetic Drugs as Geroprotectors and Anticarcinogens by ANISIMOV, VLADIMIR N., BERSTEIN, LEV M., POPOVICH, IRINA G., ZABEZHINSKI, MARK A., EGORMIN, PETER A., TYNDYK, MARGARITA L., ANIKIN, IVAN V., SEMENCHENKO, ANNA V., YASHIN, ANATOLI I.

“…Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer…”
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Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice by Anisimov, Vladimir N, Piskunova, Tatiana S, Popovich, Irina G, Zabezhinski, Mark A, Tyndyk, Margarita L, Egormin, Peter A, Yurova, Maria V, Rosenfeld, Svetlana V, Semenchenko, Anna V, Kovalenko, Irina G, Poroshina, Tatiana E, Berstein, Lev M

“…Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer. It…”
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Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice by Anisimov, Vladimir N, Popovich, Irina G, Zabezhinski, Mark A, Yurova, Maria N, Tyndyk, Margarita L, Anikin, Ivan V, Egormin, Peter A, Baldueva, Irina A, Fedoros, Elena I, Pigarev, Sergey E, Panchenko, Andrey V

“…Effects of long-term application of novel polyphenolic composition BP-C3, containing polyphenolic benzenepolycarboxylic acids, vitamins and minerals on some…”
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Biomarkers of aging, life span and spontaneous carcinogenesis in the wild type and HER-2 transgenic FVB/N female mice by Panchenko, Andrey V., Popovich, Irina G., Trashkov, Alexandr P., Egormin, Peter A., Yurova, Maria N., Tyndyk, Margarita L., Gubareva, Ekaterina A., Artyukin, Ilia N., Vasiliev, Andrey G., Khaitsev, Nikolai V., Zabezhinski, Mark A., Anisimov, Vladimir N.

“…FVB/N wild type and transgenic HER-2/neu FVB/N female mice breed at N.N. Petrov Research Institute of Oncology were under observation until natural death…”
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Insulin in aging and cancer: antidiabetic drug diabenol as geroprotector and anticarcinogen by Popovich, Irina G., Zabezhinski, Mark A., Egormin, Peter A., Tyndyk, Margarita L., Anikin, Ivan V., Spasov, Alexander A., Semenchenko, Anna V., Yashin, Anatoly I., Anisimov, Vladimir N.

“…The effects of new antidiabetic drug Diabenol ® (9-β-diethylaminoethyl-2,3-dihydroimidazo-(1,2-α)benzimidazol dihydrochloride) on life span and spontaneous…”
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Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging by Anisimov, Vladimir N, Zabezhinski, Mark A, Popovich, Irina G, Pliss, Gennady B, Bespalov, Vladimir G, Alexandrov, Valeri A, Stukov, Alexander N, Anikin, Ivan V, Alimova, Irina N, Egormin, Peter А, Panchenko, Andrey V, Piskunova, Tatiana S, Semenchenko, Anna V, Tyndyk, Margarita L, Yurova, Maria N

“…There is a growing scientific and public interest in the development of new antiaging drugs for the purposes of extending mean and/or maximum life span,…”
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Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin by Anisimov, Vladimir N, Popovich, Irina G, Zabezhinski, Mark A, Egormin, Peter A, Yurova, Maria N, Semenchenko, Anna V, Tyndyk, Margarita L, Panchenko, Andrey V, Trashkov, Alexandr P, Vasiliev, Andrey G, Khaitsev, Nikolai V

“…The perinatal (prenatal and early neonatal) period is a critical stage for hypothalamic programming of sexual differentiation as well as for the development of…”
Get full text